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Association between environmental tobacco smoke exposure across the first four years of life and manifestation of externalizing behavior problems in school-aged children / Lisa GATZKE-KOPP in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)
[article]
Titre : Association between environmental tobacco smoke exposure across the first four years of life and manifestation of externalizing behavior problems in school-aged children Type de document : Texte imprimé et/ou numérique Auteurs : Lisa GATZKE-KOPP, Auteur ; Michael T. WILLOUGHBY, Auteur ; Siri WARKENTIEN, Auteur ; Daniel PETRIE, Auteur ; Roger MILLS-KOONCE, Auteur ; Clancy BLAIR, Auteur Article en page(s) : p.1243-1252 Langues : Anglais (eng) Mots-clés : Disruptive behavior dopamine environmental exposures externalizing disorder tobacco exposure Index. décimale : PER Périodiques Résumé : BACKGROUND: Extensive literature in human and animal models has documented an association between maternal smoking during pregnancy and externalizing behavior in offspring. It remains unclear; however, the extent to which postnatal environmental smoke exposure is associated with behavioral development, particularly for children whose mothers did not smoke during pregnancy. The present study examined whether magnitude of exposure to environmental smoke across the first four years of life demonstrated a linear association with later externalizing symptoms. METHODS: Exposure was quantified through salivary cotinine measured when children were 6, 15, 24, and 48 months of age, providing a more accurate quantification of realized exposure than can be estimated from parental report of cigarettes smoked. Data were available for n = 1,096 (50% male; 44% African American) children recruited for the Family Life Project, a study of child development in areas of rural poverty. RESULTS: Analyses indicate a linear association between cotinine and children's symptoms of hyperactivity and conduct problems. This association remained significant after controlling for family poverty level, parental education, parental history of ADHD, hostility, depression, caregiver IQ, and obstetric complications. Furthermore, this association was unchanged when excluding mothers who smoked during pregnancy from the model. CONCLUSIONS: Findings are consistent with animal models demonstrating an effect of environmental exposure to nicotine on ongoing brain development in regions related to hyperactivity and impulsivity, and highlight the importance of mitigating children's exposure to environmental smoke, including sources that extend beyond the parents. En ligne : http://dx.doi.org/10.1111/jcpp.13157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1243-1252[article] Association between environmental tobacco smoke exposure across the first four years of life and manifestation of externalizing behavior problems in school-aged children [Texte imprimé et/ou numérique] / Lisa GATZKE-KOPP, Auteur ; Michael T. WILLOUGHBY, Auteur ; Siri WARKENTIEN, Auteur ; Daniel PETRIE, Auteur ; Roger MILLS-KOONCE, Auteur ; Clancy BLAIR, Auteur . - p.1243-1252.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1243-1252
Mots-clés : Disruptive behavior dopamine environmental exposures externalizing disorder tobacco exposure Index. décimale : PER Périodiques Résumé : BACKGROUND: Extensive literature in human and animal models has documented an association between maternal smoking during pregnancy and externalizing behavior in offspring. It remains unclear; however, the extent to which postnatal environmental smoke exposure is associated with behavioral development, particularly for children whose mothers did not smoke during pregnancy. The present study examined whether magnitude of exposure to environmental smoke across the first four years of life demonstrated a linear association with later externalizing symptoms. METHODS: Exposure was quantified through salivary cotinine measured when children were 6, 15, 24, and 48 months of age, providing a more accurate quantification of realized exposure than can be estimated from parental report of cigarettes smoked. Data were available for n = 1,096 (50% male; 44% African American) children recruited for the Family Life Project, a study of child development in areas of rural poverty. RESULTS: Analyses indicate a linear association between cotinine and children's symptoms of hyperactivity and conduct problems. This association remained significant after controlling for family poverty level, parental education, parental history of ADHD, hostility, depression, caregiver IQ, and obstetric complications. Furthermore, this association was unchanged when excluding mothers who smoked during pregnancy from the model. CONCLUSIONS: Findings are consistent with animal models demonstrating an effect of environmental exposure to nicotine on ongoing brain development in regions related to hyperactivity and impulsivity, and highlight the importance of mitigating children's exposure to environmental smoke, including sources that extend beyond the parents. En ligne : http://dx.doi.org/10.1111/jcpp.13157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development / Caitlin S. M. COWAN in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)
[article]
Titre : Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development Type de document : Texte imprimé et/ou numérique Auteurs : Caitlin S. M. COWAN, Auteur ; Timothy G. DINAN, Auteur ; John F. CRYAN, Auteur Article en page(s) : p.353-371 Langues : Anglais (eng) Mots-clés : Cognitive development child development early-life experience environmental exposures neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : The gut microbiota is a vast, complex, and fascinating ecosystem of microorganisms that resides in the human gastrointestinal tract. As an integral part of the microbiota-gut-brain axis, it is now being recognized that the microbiota is a modulator of brain and behavior, across species. Intriguingly, periods of change in the microbiota coincide with the development of other body systems and particularly the brain. We hypothesize that these times of parallel development are biologically relevant, corresponding to 'sensitive periods' or 'critical windows' in the development of the microbiota-gut-brain axis. Specifically, signals from the microbiota during these periods are hypothesized to be crucial for establishing appropriate communication along the axis throughout the life span. In other words, the microbiota is hypothesized to act like an expected input to calibrate the development of the microbiota-gut-brain axis. The absence or disruption of the microbiota during specific developmental windows would therefore be expected to have a disproportionate effect on specific functions or potentially for regulation of the system as a whole. Evidence for microbial modulation of neurocognitive development and neurodevelopmental risk is discussed in light of this hypothesis, finishing with a focus on the challenges that lay ahead for the future study of the microbiota-gut-brain axis during development. En ligne : http://dx.doi.org/10.1111/jcpp.13156 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.353-371[article] Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development [Texte imprimé et/ou numérique] / Caitlin S. M. COWAN, Auteur ; Timothy G. DINAN, Auteur ; John F. CRYAN, Auteur . - p.353-371.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.353-371
Mots-clés : Cognitive development child development early-life experience environmental exposures neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : The gut microbiota is a vast, complex, and fascinating ecosystem of microorganisms that resides in the human gastrointestinal tract. As an integral part of the microbiota-gut-brain axis, it is now being recognized that the microbiota is a modulator of brain and behavior, across species. Intriguingly, periods of change in the microbiota coincide with the development of other body systems and particularly the brain. We hypothesize that these times of parallel development are biologically relevant, corresponding to 'sensitive periods' or 'critical windows' in the development of the microbiota-gut-brain axis. Specifically, signals from the microbiota during these periods are hypothesized to be crucial for establishing appropriate communication along the axis throughout the life span. In other words, the microbiota is hypothesized to act like an expected input to calibrate the development of the microbiota-gut-brain axis. The absence or disruption of the microbiota during specific developmental windows would therefore be expected to have a disproportionate effect on specific functions or potentially for regulation of the system as a whole. Evidence for microbial modulation of neurocognitive development and neurodevelopmental risk is discussed in light of this hypothesis, finishing with a focus on the challenges that lay ahead for the future study of the microbiota-gut-brain axis during development. En ligne : http://dx.doi.org/10.1111/jcpp.13156 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420