22 recherche sur le mot-clé 'environmental factors'

Mapping the link between socio-economic factors, autistic traits and mental health across different settings / Teresa DEL BIANCO in Autism, 28-5 (May 2024)  

Public ISBD [article]  inAutism > 28-5 (May 2024) . - p.1280-1296 Titre : Mapping the link between socio-economic factors, autistic traits and mental health across different settings Type de document : texte imprimé Auteurs : Teresa DEL BIANCO, Auteur ; Georgia LOCKWOOD ESTRIN, Auteur ; Julian TILLMANN, Auteur ; Bethany OAKLEY, Auteur ; Daisy CRAWLEY, Auteur ; Antonia SAN JOSE CACERES, Auteur ; Hannah HAYWARD, Auteur ; Mandy POTTER, Auteur ; Wendy MACKAY, Auteur ; Petrusa SMIT, Auteur ; Carlie DU PLESSIS, Auteur ; Lucy BRINK, Auteur ; Priscilla SPRINGER, Auteur ; Hein ODENDAAL, Auteur ; Tony CHARMAN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Simon BARON-COHEN, Auteur ; Sven BÖLTE, Auteur ; Mark JOHNSON, Auteur ; Declan G.M. MURPHY, Auteur ; Jan K. BUITELAAR, Auteur ; Eva LOTH, Auteur ; Emily J.H. JONES, Auteur Article en page(s) : p.1280-1296 Langues : Anglais (eng) Mots-clés : autism spectrum disorders  environmental factors Index. décimale : PER Périodiques Résumé : Autistic individuals experience higher rates of externalising and internalising symptoms that may vary with environmental factors. However, there is limited research on variation across settings that may highlight common factors with globally generalisable effects. Data were taken from two cohorts: a multinational European sample (n = 764; 453 autistic; 311 non-autistic; 6-30 years), and a South African sample (n = 100 non-autistic; 3-11 years). An exploratory factor analysis aggregated clinical (Verbal Comprehension and Perceptual Index), adaptive traits (Vineland Adaptive Behaviour Scale) and socio-economic variables (parental employment and education, home and family characteristics) in each cohort separately. With regression, we investigated the effect of these factors and autistic traits on internalising and externalising scores (measured with the Strengths and Difficulties Questionnaire). Cohorts showed similar four-factor structures (Person Characteristics, Family System, Parental and Material Resources). The 'Family System' factor captured family size and maternal factors and was associated with lower internalising and externalising symptoms in both cohorts. In the European cohort, high autistic traits reduced this effect; the opposite was found in the South Africa cohort. Our exploratory findings from two separate analyses represent consistent evidence that Family System is associated with internalising and externalising symptoms, with a context-specific impact in persons with high autism traits. Lay Abstract Autistic individuals are more likely than non-autistic individuals to experience a mental health condition in their lifetime, and this includes externalising and internalising symptoms. We know very little about how different environments and family conditions impact these symptoms for autistic individuals. Improving our understanding of these relationships is important so that we can identify individuals who may be in greater need of support. In this article, we seek to improve our understanding of how environmental and family conditions impact externalising and internalising symptoms in autistic and non-autistic people. To do this, we conducted analyses with two cohorts in very different settings - in Europe and South Africa - to ensure our findings are globally representative. We used advanced statistical methods to establish environmental and family conditions that were similar to each other, and which could be combined into specific 'factors'. We found that four similar 'factors' could be identified in the two cohorts. These were distinguished by personal characteristics and environmental conditions of individuals, and were named Person Characteristics, Family System, Parental and Material Resources. Interestingly, just 'Family System' was associated with internalising and externalising symptoms, and this was the same in both cohorts. We also found that having high traits of autism impacted this relationship between Family System and mental health conditions with opposite directions in the two settings. These results show that characteristics in the Family System are associated with internalising and externalising symptoms, and autistic persons are particularly impacted, reinforcing the notion that family stressors are important to consider when implementing policy and practice related to improving the mental health of autistic people. En ligne : https://dx.doi.org/10.1177/13623613231200297 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=527 [article] Mapping the link between socio-economic factors, autistic traits and mental health across different settings [texte imprimé] / Teresa DEL BIANCO, Auteur ; Georgia LOCKWOOD ESTRIN, Auteur ; Julian TILLMANN, Auteur ; Bethany OAKLEY, Auteur ; Daisy CRAWLEY, Auteur ; Antonia SAN JOSE CACERES, Auteur ; Hannah HAYWARD, Auteur ; Mandy POTTER, Auteur ; Wendy MACKAY, Auteur ; Petrusa SMIT, Auteur ; Carlie DU PLESSIS, Auteur ; Lucy BRINK, Auteur ; Priscilla SPRINGER, Auteur ; Hein ODENDAAL, Auteur ; Tony CHARMAN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Simon BARON-COHEN, Auteur ; Sven BÖLTE, Auteur ; Mark JOHNSON, Auteur ; Declan G.M. MURPHY, Auteur ; Jan K. BUITELAAR, Auteur ; Eva LOTH, Auteur ; Emily J.H. JONES, Auteur . - p.1280-1296. Langues : Anglais (eng) in Autism > 28-5 (May 2024) . - p.1280-1296 Mots-clés : autism spectrum disorders  environmental factors Index. décimale : PER Périodiques Résumé : Autistic individuals experience higher rates of externalising and internalising symptoms that may vary with environmental factors. However, there is limited research on variation across settings that may highlight common factors with globally generalisable effects. Data were taken from two cohorts: a multinational European sample (n = 764; 453 autistic; 311 non-autistic; 6-30 years), and a South African sample (n = 100 non-autistic; 3-11 years). An exploratory factor analysis aggregated clinical (Verbal Comprehension and Perceptual Index), adaptive traits (Vineland Adaptive Behaviour Scale) and socio-economic variables (parental employment and education, home and family characteristics) in each cohort separately. With regression, we investigated the effect of these factors and autistic traits on internalising and externalising scores (measured with the Strengths and Difficulties Questionnaire). Cohorts showed similar four-factor structures (Person Characteristics, Family System, Parental and Material Resources). The 'Family System' factor captured family size and maternal factors and was associated with lower internalising and externalising symptoms in both cohorts. In the European cohort, high autistic traits reduced this effect; the opposite was found in the South Africa cohort. Our exploratory findings from two separate analyses represent consistent evidence that Family System is associated with internalising and externalising symptoms, with a context-specific impact in persons with high autism traits. Lay Abstract Autistic individuals are more likely than non-autistic individuals to experience a mental health condition in their lifetime, and this includes externalising and internalising symptoms. We know very little about how different environments and family conditions impact these symptoms for autistic individuals. Improving our understanding of these relationships is important so that we can identify individuals who may be in greater need of support. In this article, we seek to improve our understanding of how environmental and family conditions impact externalising and internalising symptoms in autistic and non-autistic people. To do this, we conducted analyses with two cohorts in very different settings - in Europe and South Africa - to ensure our findings are globally representative. We used advanced statistical methods to establish environmental and family conditions that were similar to each other, and which could be combined into specific 'factors'. We found that four similar 'factors' could be identified in the two cohorts. These were distinguished by personal characteristics and environmental conditions of individuals, and were named Person Characteristics, Family System, Parental and Material Resources. Interestingly, just 'Family System' was associated with internalising and externalising symptoms, and this was the same in both cohorts. We also found that having high traits of autism impacted this relationship between Family System and mental health conditions with opposite directions in the two settings. These results show that characteristics in the Family System are associated with internalising and externalising symptoms, and autistic persons are particularly impacted, reinforcing the notion that family stressors are important to consider when implementing policy and practice related to improving the mental health of autistic people. En ligne : https://dx.doi.org/10.1177/13623613231200297 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=527

The role of zinc dysregulation in Autism Spectrum Disorder: A systematic review of genetic and environmental influences and therapeutic potential / Mohammed Rushdhi IRFAN ; Ali RAJA ; Mohamed Akram SATTAR ; Alzahra’a AL MATAIRI ; Rushdan Mohamed FIRDOUS ; Aksh SHARMA ; Jamil ALGHANEM ; Adel KALOU ; Youmna Hassan Hashim ABDALGADER ; Wael KALOU ; Ahmed YAQINUDDIN in Research in Autism, 124 (June 2025)  

Public ISBD [article]  inResearch in Autism > 124 (June 2025) . - 202579 Titre : The role of zinc dysregulation in Autism Spectrum Disorder: A systematic review of genetic and environmental influences and therapeutic potential Type de document : texte imprimé Auteurs : Mohammed Rushdhi IRFAN, Auteur ; Ali RAJA, Auteur ; Mohamed Akram SATTAR, Auteur ; Alzahra’a AL MATAIRI, Auteur ; Rushdan Mohamed FIRDOUS, Auteur ; Aksh SHARMA, Auteur ; Jamil ALGHANEM, Auteur ; Adel KALOU, Auteur ; Youmna Hassan Hashim ABDALGADER, Auteur ; Wael KALOU, Auteur ; Ahmed YAQINUDDIN, Auteur Article en page(s) : 202579 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Zinc dysregulation  Neurodevelopment  Genetic factors  Environmental factors  Zinc supplementation  Synaptic function Index. décimale : PER Périodiques Résumé : This systematic review examines the role of zinc (Zn) dysregulation in the development and management of Autism Spectrum Disorder (ASD), focusing on genetic and environmental factors, as well as the therapeutic potential of Zn supplementation. Zn is crucial for neurodevelopmental processes, and disruptions in Zn homeostasis have been associated with ASD symptoms. Genetic factors, such as mutations in Zn transporter genes (such as, SLC39A8, SHANK3), impact Zn regulation and synaptic function, contributing to ASD pathophysiology. Additionally, prenatal and early-life environmental exposures (such as, maternal diet, heavy metal exposure) can exacerbate Zn dysregulation. This review synthesizes data from both human and animal studies to explore these mechanisms and evaluates clinical trials on Zn supplementation, which show mixed results in symptom management. The findings highlight the need for standardized Zn assessment and intervention protocols to further investigate Zn s role as a therapeutic target for ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202579 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=556 [article] The role of zinc dysregulation in Autism Spectrum Disorder: A systematic review of genetic and environmental influences and therapeutic potential [texte imprimé] / Mohammed Rushdhi IRFAN, Auteur ; Ali RAJA, Auteur ; Mohamed Akram SATTAR, Auteur ; Alzahra’a AL MATAIRI, Auteur ; Rushdan Mohamed FIRDOUS, Auteur ; Aksh SHARMA, Auteur ; Jamil ALGHANEM, Auteur ; Adel KALOU, Auteur ; Youmna Hassan Hashim ABDALGADER, Auteur ; Wael KALOU, Auteur ; Ahmed YAQINUDDIN, Auteur . - 202579. Langues : Anglais (eng) in Research in Autism > 124 (June 2025) . - 202579 Mots-clés : Autism Spectrum Disorder  Zinc dysregulation  Neurodevelopment  Genetic factors  Environmental factors  Zinc supplementation  Synaptic function Index. décimale : PER Périodiques Résumé : This systematic review examines the role of zinc (Zn) dysregulation in the development and management of Autism Spectrum Disorder (ASD), focusing on genetic and environmental factors, as well as the therapeutic potential of Zn supplementation. Zn is crucial for neurodevelopmental processes, and disruptions in Zn homeostasis have been associated with ASD symptoms. Genetic factors, such as mutations in Zn transporter genes (such as, SLC39A8, SHANK3), impact Zn regulation and synaptic function, contributing to ASD pathophysiology. Additionally, prenatal and early-life environmental exposures (such as, maternal diet, heavy metal exposure) can exacerbate Zn dysregulation. This review synthesizes data from both human and animal studies to explore these mechanisms and evaluates clinical trials on Zn supplementation, which show mixed results in symptom management. The findings highlight the need for standardized Zn assessment and intervention protocols to further investigate Zn s role as a therapeutic target for ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202579 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=556

Factors underlying differences in knowledge, explicit stigma and implicit biases towards autism across Hong Kong, the United Kingdom and the United States / Yulin CHENG in Autism, 29-4 (April 2025)  

Public ISBD [article]  inAutism > 29-4 (April 2025) . - p.868-883 Titre : Factors underlying differences in knowledge, explicit stigma and implicit biases towards autism across Hong Kong, the United Kingdom and the United States Type de document : texte imprimé Auteurs : Yulin CHENG, Auteur ; Patrick DWYER, Auteur ; Connor T. KEATING, Auteur Article en page(s) : p.868-883 Langues : Anglais (eng) Mots-clés : autism spectrum disorders  collectivism  cross-cultural  culture  environmental factors  explicit attitudes  implicit biases  individualism  knowledge  stigma Index. décimale : PER Périodiques Résumé : A growing literature suggests that there is cross-cultural variation in levels of autism-related stigma, which may partially be explained by differences in cultural orientation or autism-related knowledge between countries. This literature has relied heavily on self-report measures of explicit attitudes towards autism; little research has examined implicit biases, and whether these implicit biases vary across cultures. Thus, here we had two aims: (1) to assess the contribution of knowledge and cultural orientation to both explicit stigma and implicit biases, and (2) to compare autism-related knowledge, explicit stigma, and implicit biases across university students in Hong Kong (n = 119), the United Kingdom (n = 120), and the United States (n = 122). Replicating prior work, we found that explicit stigma was predicted by less accurate knowledge, lower horizontal collectivism, greater vertical individualism, and higher implicit biases. Implicit biases were directly predicted by age and explicit stigma, and indirectly predicted by vertical individualism (positively) and horizontal collectivism (negatively) via explicit stigma. Knowledge and explicit stigma differed across countries, even after accounting for covariates: students in Hong Kong displayed less accurate knowledge, and higher explicit stigma towards autism, than those in the United Kingdom and United States. However, implicit biases did not differ between countries.Lay abstract Attitudes towards autism vary across countries. Some of this variation could reflect differences in cultural values across countries, or differences in how much people know about autism. Until now, most research on this topic has asked people directly about their attitudes towards interacting with autistic people. As a result, we understand little about why some people unconsciously hold negative attitudes towards autism, and whether these unconscious attitudes vary across countries. We studied explicit attitudes (willingness to interact), implicit attitudes (unconscious beliefs), knowledge about autism, and cultural values in university students from Hong Kong, the United Kingdom and the United States. We found that people were less willing to interact with autistic people if they knew less about autism, aligned with a competitive and hierarchical society ('vertical individualism'), did not see themselves as part of a collective whose members are equal (less 'horizontal collectivism'), and if they unconcsciously associated autism with negative attributes. Students in Hong Kong were less willing to interact with autistic people and had less understanding of autism compared to those in the United Kingdom and the United States. Unconscious biases did not differ across countries. Our findings highlight the need to combat misconceptions about autism to improve attitudes towards autistic people, especially in Hong Kong. Unfortunately, our results suggest that acquiring more accurate knowledge may not be sufficient to alter unconscious biases. Further research is needed to determine the factors underlying unconscious biases. En ligne : https://dx.doi.org/10.1177/13623613241290565 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552 [article] Factors underlying differences in knowledge, explicit stigma and implicit biases towards autism across Hong Kong, the United Kingdom and the United States [texte imprimé] / Yulin CHENG, Auteur ; Patrick DWYER, Auteur ; Connor T. KEATING, Auteur . - p.868-883. Langues : Anglais (eng) in Autism > 29-4 (April 2025) . - p.868-883 Mots-clés : autism spectrum disorders  collectivism  cross-cultural  culture  environmental factors  explicit attitudes  implicit biases  individualism  knowledge  stigma Index. décimale : PER Périodiques Résumé : A growing literature suggests that there is cross-cultural variation in levels of autism-related stigma, which may partially be explained by differences in cultural orientation or autism-related knowledge between countries. This literature has relied heavily on self-report measures of explicit attitudes towards autism; little research has examined implicit biases, and whether these implicit biases vary across cultures. Thus, here we had two aims: (1) to assess the contribution of knowledge and cultural orientation to both explicit stigma and implicit biases, and (2) to compare autism-related knowledge, explicit stigma, and implicit biases across university students in Hong Kong (n = 119), the United Kingdom (n = 120), and the United States (n = 122). Replicating prior work, we found that explicit stigma was predicted by less accurate knowledge, lower horizontal collectivism, greater vertical individualism, and higher implicit biases. Implicit biases were directly predicted by age and explicit stigma, and indirectly predicted by vertical individualism (positively) and horizontal collectivism (negatively) via explicit stigma. Knowledge and explicit stigma differed across countries, even after accounting for covariates: students in Hong Kong displayed less accurate knowledge, and higher explicit stigma towards autism, than those in the United Kingdom and United States. However, implicit biases did not differ between countries.Lay abstract Attitudes towards autism vary across countries. Some of this variation could reflect differences in cultural values across countries, or differences in how much people know about autism. Until now, most research on this topic has asked people directly about their attitudes towards interacting with autistic people. As a result, we understand little about why some people unconsciously hold negative attitudes towards autism, and whether these unconscious attitudes vary across countries. We studied explicit attitudes (willingness to interact), implicit attitudes (unconscious beliefs), knowledge about autism, and cultural values in university students from Hong Kong, the United Kingdom and the United States. We found that people were less willing to interact with autistic people if they knew less about autism, aligned with a competitive and hierarchical society ('vertical individualism'), did not see themselves as part of a collective whose members are equal (less 'horizontal collectivism'), and if they unconcsciously associated autism with negative attributes. Students in Hong Kong were less willing to interact with autistic people and had less understanding of autism compared to those in the United Kingdom and the United States. Unconscious biases did not differ across countries. Our findings highlight the need to combat misconceptions about autism to improve attitudes towards autistic people, especially in Hong Kong. Unfortunately, our results suggest that acquiring more accurate knowledge may not be sufficient to alter unconscious biases. Further research is needed to determine the factors underlying unconscious biases. En ligne : https://dx.doi.org/10.1177/13623613241290565 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552

A co-twin-control study of altered sensory processing in autism / Janina NEUFELD in Autism, 25-5 (July 2021)  

Public ISBD [article]  inAutism > 25-5 (July 2021) . - p.1422-1432 Titre : A co-twin-control study of altered sensory processing in autism Type de document : texte imprimé Auteurs : Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.1422-1432 Langues : Anglais (eng) Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] A co-twin-control study of altered sensory processing in autism [texte imprimé] / Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur . - p.1422-1432. Langues : Anglais (eng) in Autism > 25-5 (July 2021) . - p.1422-1432 Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

A co-twin-control study of altered sensory processing in autism / Janina NEUFELD in Autism, 26-5 (July 2022)  

Public ISBD [article]  inAutism > 26-5 (July 2022) . - p.1422-1432 Titre : A co-twin-control study of altered sensory processing in autism Type de document : texte imprimé Auteurs : Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.1422-1432 Langues : Anglais (eng) Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484 [article] A co-twin-control study of altered sensory processing in autism [texte imprimé] / Janina NEUFELD, Auteur ; Mark J. TAYLOR, Auteur ; Karl LUNDIN REMNÉLIUS, Auteur ; Johan ISAKSSON, Auteur ; Paul LICHTENSTEIN, Auteur ; Sven BÖLTE, Auteur . - p.1422-1432. Langues : Anglais (eng) in Autism > 26-5 (July 2022) . - p.1422-1432 Mots-clés : Anxiety Disorders  Attention Deficit Disorder with Hyperactivity  Autism Spectrum Disorder  Autistic Disorder  Humans  Perception  autism spectrum disorders  behavioral genetics  environmental factors  sensory processing  sensory profile  twin design  potential conflicts of interest with respect to the research, authorship, and/or  publication of this article: S. B. discloses that he has in the last 3 years  acted as an author, consultant or lecturer for Medice, Roche. Hogrefe,  Kohlhammer, and UTB. Index. décimale : PER Périodiques Résumé : Individuals diagnosed with autism often describe that they process sensory information differently from others, and many experience sensory issues as problematic. For instance, an increased sensitivity to smells or sounds can make participating in social settings challenging. While sensory issues are now part of the diagnostic criteria for autism, they also co-occur with other psychiatric diagnoses such as attention deficit hyperactivity disorder and anxiety disorders. It is unclear to what extent the relationship between autism and alterations in sensory processing are due to genetics or environment. In addition, more research is needed on how autism, as compared to other diagnoses, is associated with sensory issues. Using a twin study, we found that genetic factors influenced self-reported reactivity to sensory stimuli in autism while environmental factors influenced other sensory issues (e.g. difficulties in detecting or differentiating sensory input). Hence, sensory hyper-reactivity might be an early onset core feature of autism, while other domains of alterations in sensory processing might develop later, influenced by the environment. Moreover, autism was more strongly associated with sensory issues related to increased sensitivity/reactivity as compared to other psychiatric diagnoses. However, attention deficit hyperactivity disorder was more strongly related to deficits in detecting/differentiating sensory stimuli and with an increased drive to seek sensory input. Our results indicate that sensory issues are not specific to autism, but that some aspects of altered sensory processing are more relevant for autism than for other diagnoses. En ligne : http://dx.doi.org/10.1177/1362361321991255 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484

LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy / Zia CHOUDHRY in Journal of Child Psychology and Psychiatry, 53-8 (August 2012)  

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Novel targets for autism spectrum disorder: Recent developments, challenges, and future perspectives / Shubham DWIVEDI in Research in Autism, 133 (May 2026)  

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Prenatal exposure to paternal smoking and likelihood for autism spectrum disorder in Autism, 25-7 (October 2021)  

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Prenatal exposure to paternal smoking and likelihood for autism spectrum disorder / Bora KIM in Autism, 26-7 (October 2022)  

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Bilingualism effects on cognition in autistic children are not all-or-nothing: The role of socioeconomic status in intellectual skills in bilingual autistic children / Eleni PERISTERI in Autism, 26-8 (November 2022)  

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