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Titre : Oncogenes Involved in the Etiology of Autism Type de document : Texte imprimé et/ou numérique Auteurs : A.J. RUSSO, Auteur Article en page(s) : p.11-13 Langues : Anglais (eng) Mots-clés : epidermal growth factor receptor (EGFR) epidermal growth factor (EGF) hepatocyte growth factor receptor (HGFR) cMet hepatocyte growth factor (HGF) autism Index. décimale : PER Périodiques Résumé : Epidermal growth factor receptor (EGFR) gene and Hepatocyte Growth Factor Receptor gene, c-Met, are proto-oncogenes which code for cell-surface tyrosine kinase receptors, EGFR and hepatocyte growth factor (HGF), respectively. These membrane receptors are stimulated by ligands, epidermal growth factor (EGF) and hepatocyte growth factor (HGF), and then, through a cascade of reactions, regulate several important cell events such as growth, motility, and morphogenesis. This editorial presents a cursory look at the evidence that these proto-oncogenes, and their products, are involved in the etiology of neurobehavioral disorders, such as autism. En ligne : https://dx.doi.org/10.4137/AUI.S14280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409
in Autism Insights > (February 2014) . - p.11-13[article] Oncogenes Involved in the Etiology of Autism [Texte imprimé et/ou numérique] / A.J. RUSSO, Auteur . - p.11-13.
Langues : Anglais (eng)
in Autism Insights > (February 2014) . - p.11-13
Mots-clés : epidermal growth factor receptor (EGFR) epidermal growth factor (EGF) hepatocyte growth factor receptor (HGFR) cMet hepatocyte growth factor (HGF) autism Index. décimale : PER Périodiques Résumé : Epidermal growth factor receptor (EGFR) gene and Hepatocyte Growth Factor Receptor gene, c-Met, are proto-oncogenes which code for cell-surface tyrosine kinase receptors, EGFR and hepatocyte growth factor (HGF), respectively. These membrane receptors are stimulated by ligands, epidermal growth factor (EGF) and hepatocyte growth factor (HGF), and then, through a cascade of reactions, regulate several important cell events such as growth, motility, and morphogenesis. This editorial presents a cursory look at the evidence that these proto-oncogenes, and their products, are involved in the etiology of neurobehavioral disorders, such as autism. En ligne : https://dx.doi.org/10.4137/AUI.S14280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409