1 recherche sur le mot-clé 'hyperactivity/impulsivity and inattention'

Genetic and phenotypic evidence of the predictive validity of preschool parent reports of hyperactivity/impulsivity and inattention / Ginette DIONNE in Development and Psychopathology, 37-2 (May 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-2 (May 2025) . - p.590-602 Titre : Genetic and phenotypic evidence of the predictive validity of preschool parent reports of hyperactivity/impulsivity and inattention Type de document : texte imprimé Auteurs : Ginette DIONNE, Auteur ; Sara MASCHERETTI, Auteur ; Bei FENG, Auteur ; Hélène PARADIS, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur Article en page(s) : p.590-602 Langues : Anglais (eng) Mots-clés : ADHD  genetic modeling  group-based trajectory analysis  hyperactivity/impulsivity and inattention  preschool parent reports Index. décimale : PER Périodiques Résumé : To determine the validity of parent reports (PRs) of ADHD in preschoolers, we assessed hyperactivity/impulsivity (HI) and inattention (IN) in 1114 twins with PRs at 1.5, 2.5, 4, 5, 14, 15, and 17 years, and teacher-reports at 6, 7, 9, 10, and 12. We examined if preschool PRs (1) predict high HI/IN trajectories, and (2) capture genetic contributions to HI/IN into adolescence. Group-based trajectory analyses identified three 6-17 years trajectories for both HI and IN, including small groups with high HI (N = 88, 10.4%, 77% boys) and IN (N = 158, 17.3%, 75% boys). Controlling for sex, each unit of HI PRs starting at 1.5 years and at 4 years for IN, increased more than 2-fold the risk of belonging to the high trajectory, with incremental contributions (Odds Ratios = 2.5-4.5) at subsequent ages. Quantitative genetic analyses showed that genetic contributions underlying preschool PRs accounted for up to a quarter and a third of the heritability of later HI and IN, respectively. Genes underlying 1.5-year HI and 4-year IN contributed to 6 of 8 later HI and IN time-points and largely explained the corresponding phenotypic correlations. Results provide phenotypic and genetic evidence that preschool parent reports of HI and IN are valid means to predict developmental risk of ADHD. En ligne : https://dx.doi.org/10.1017/S095457942400035X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552 [article] Genetic and phenotypic evidence of the predictive validity of preschool parent reports of hyperactivity/impulsivity and inattention [texte imprimé] / Ginette DIONNE, Auteur ; Sara MASCHERETTI, Auteur ; Bei FENG, Auteur ; Hélène PARADIS, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur . - p.590-602. Langues : Anglais (eng) in Development and Psychopathology > 37-2 (May 2025) . - p.590-602 Mots-clés : ADHD  genetic modeling  group-based trajectory analysis  hyperactivity/impulsivity and inattention  preschool parent reports Index. décimale : PER Périodiques Résumé : To determine the validity of parent reports (PRs) of ADHD in preschoolers, we assessed hyperactivity/impulsivity (HI) and inattention (IN) in 1114 twins with PRs at 1.5, 2.5, 4, 5, 14, 15, and 17 years, and teacher-reports at 6, 7, 9, 10, and 12. We examined if preschool PRs (1) predict high HI/IN trajectories, and (2) capture genetic contributions to HI/IN into adolescence. Group-based trajectory analyses identified three 6-17 years trajectories for both HI and IN, including small groups with high HI (N = 88, 10.4%, 77% boys) and IN (N = 158, 17.3%, 75% boys). Controlling for sex, each unit of HI PRs starting at 1.5 years and at 4 years for IN, increased more than 2-fold the risk of belonging to the high trajectory, with incremental contributions (Odds Ratios = 2.5-4.5) at subsequent ages. Quantitative genetic analyses showed that genetic contributions underlying preschool PRs accounted for up to a quarter and a third of the heritability of later HI and IN, respectively. Genes underlying 1.5-year HI and 4-year IN contributed to 6 of 8 later HI and IN time-points and largely explained the corresponding phenotypic correlations. Results provide phenotypic and genetic evidence that preschool parent reports of HI and IN are valid means to predict developmental risk of ADHD. En ligne : https://dx.doi.org/10.1017/S095457942400035X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552