Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
3 recherche sur le mot-clé 'magnetic resonance imaging (MRI)'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults / Gizem Y. YILDIZ in Journal of Autism and Developmental Disorders, 51-2 (February 2021)
[article]
Titre : Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults Type de document : Texte imprimé et/ou numérique Auteurs : Gizem Y. YILDIZ, Auteur ; Julian S. VILSTEN, Auteur ; Amy Siobhan MILLARD, Auteur ; Philippe A. CHOUINARD, Auteur Article en page(s) : p.405-417 Langues : Anglais (eng) Mots-clés : Autism-spectrum quotient (AQ) Grey-matter thickness Magnetic resonance imaging (MRI) Primary visual area (V1) Retinotopy Index. décimale : PER Périodiques Résumé : We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males; M(Age)?=?26.4 years, SD(Age)?=?4.0 years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits. En ligne : http://dx.doi.org/10.1007/s10803-020-04553-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440
in Journal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.405-417[article] Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults [Texte imprimé et/ou numérique] / Gizem Y. YILDIZ, Auteur ; Julian S. VILSTEN, Auteur ; Amy Siobhan MILLARD, Auteur ; Philippe A. CHOUINARD, Auteur . - p.405-417.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.405-417
Mots-clés : Autism-spectrum quotient (AQ) Grey-matter thickness Magnetic resonance imaging (MRI) Primary visual area (V1) Retinotopy Index. décimale : PER Périodiques Résumé : We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males; M(Age)?=?26.4 years, SD(Age)?=?4.0 years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits. En ligne : http://dx.doi.org/10.1007/s10803-020-04553-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440 Executive function and functional and structural brain differences in middle-age adults with autism spectrum disorder / B. Blair BRADEN in Autism Research, 10-12 (December 2017)
[article]
Titre : Executive function and functional and structural brain differences in middle-age adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : B. Blair BRADEN, Auteur ; Christopher J. SMITH, Auteur ; Amiee THOMPSON, Auteur ; Tyler K. GLASPY, Auteur ; Emily WOOD, Auteur ; Divya VATSA, Auteur ; Angela E. ABBOTT, Auteur ; Samuel C. MCGEE, Auteur ; Leslie C. BAXTER, Auteur Article en page(s) : p.1945-1959 Langues : Anglais (eng) Mots-clés : autism aging executive function magnetic resonance imaging (MRI) functional connectivity diffusion tensor imaging hippocampus working memory Index. décimale : PER Périodiques Résumé : There is a rapidly growing group of aging adults with autism spectrum disorder (ASD) who may have unique needs, yet cognitive and brain function in older adults with ASD is understudied. We combined functional and structural neuroimaging and neuropsychological tests to examine differences between middle-aged men with ASD and matched neurotypical (NT) men. Participants (ASD, n?=?16; NT, n?=?17) aged 40–64 years were well-matched according to age, IQ (range: 83–131), and education (range: 9–20 years). Middle-age adults with ASD made more errors on an executive function task (Wisconsin Card Sorting Test) but performed similarly to NT adults on tests of delayed verbal memory (Rey Auditory Verbal Learning Test) and local visual search (Embedded Figures Task). Independent component analysis of a functional MRI working memory task (n-back) completed by most participants (ASD?=?14, NT?=?17) showed decreased engagement of a cortico-striatal-thalamic-cortical neural network in older adults with ASD. Structurally, older adults with ASD had reduced bilateral hippocampal volumes, as measured by FreeSurfer. Findings expand our understanding of ASD as a lifelong condition with persistent cognitive and functional and structural brain differences evident at middle-age. Autism Res 2017, 10: 1945–1959. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary We compared cognitive abilities and brain measures between 16 middle-age men with high-functioning autism spectrum disorder (ASD) and 17 typical middle-age men to better understand how aging affects an older group of adults with ASD. Men with ASD made more errors on a test involving flexible thinking, had less activity in a flexible thinking brain network, and had smaller volume of a brain structure related to memory than typical men. We will follow these older adults over time to determine if aging changes are greater for individuals with ASD. En ligne : http://dx.doi.org/10.1002/aur.1842 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=323
in Autism Research > 10-12 (December 2017) . - p.1945-1959[article] Executive function and functional and structural brain differences in middle-age adults with autism spectrum disorder [Texte imprimé et/ou numérique] / B. Blair BRADEN, Auteur ; Christopher J. SMITH, Auteur ; Amiee THOMPSON, Auteur ; Tyler K. GLASPY, Auteur ; Emily WOOD, Auteur ; Divya VATSA, Auteur ; Angela E. ABBOTT, Auteur ; Samuel C. MCGEE, Auteur ; Leslie C. BAXTER, Auteur . - p.1945-1959.
Langues : Anglais (eng)
in Autism Research > 10-12 (December 2017) . - p.1945-1959
Mots-clés : autism aging executive function magnetic resonance imaging (MRI) functional connectivity diffusion tensor imaging hippocampus working memory Index. décimale : PER Périodiques Résumé : There is a rapidly growing group of aging adults with autism spectrum disorder (ASD) who may have unique needs, yet cognitive and brain function in older adults with ASD is understudied. We combined functional and structural neuroimaging and neuropsychological tests to examine differences between middle-aged men with ASD and matched neurotypical (NT) men. Participants (ASD, n?=?16; NT, n?=?17) aged 40–64 years were well-matched according to age, IQ (range: 83–131), and education (range: 9–20 years). Middle-age adults with ASD made more errors on an executive function task (Wisconsin Card Sorting Test) but performed similarly to NT adults on tests of delayed verbal memory (Rey Auditory Verbal Learning Test) and local visual search (Embedded Figures Task). Independent component analysis of a functional MRI working memory task (n-back) completed by most participants (ASD?=?14, NT?=?17) showed decreased engagement of a cortico-striatal-thalamic-cortical neural network in older adults with ASD. Structurally, older adults with ASD had reduced bilateral hippocampal volumes, as measured by FreeSurfer. Findings expand our understanding of ASD as a lifelong condition with persistent cognitive and functional and structural brain differences evident at middle-age. Autism Res 2017, 10: 1945–1959. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary We compared cognitive abilities and brain measures between 16 middle-age men with high-functioning autism spectrum disorder (ASD) and 17 typical middle-age men to better understand how aging affects an older group of adults with ASD. Men with ASD made more errors on a test involving flexible thinking, had less activity in a flexible thinking brain network, and had smaller volume of a brain structure related to memory than typical men. We will follow these older adults over time to determine if aging changes are greater for individuals with ASD. En ligne : http://dx.doi.org/10.1002/aur.1842 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=323 Exposure to prenatal maternal distress and infant white matter neurodevelopment / Catherine H. DEMERS in Development and Psychopathology, 33-5 (December 2021)
[article]
Titre : Exposure to prenatal maternal distress and infant white matter neurodevelopment Type de document : Texte imprimé et/ou numérique Auteurs : Catherine H. DEMERS, Auteur ; Maria M. BAGONIS, Auteur ; Khalid AL-ALI, Auteur ; Sarah E. GARCIA, Auteur ; Martin A. STYNER, Auteur ; John H. GILMORE, Auteur ; M. Camille HOFFMAN, Auteur ; Benjamin L. HANKIN, Auteur ; Elysia Poggi DAVIS, Auteur Article en page(s) : p.1526-1538 Langues : Anglais (eng) Mots-clés : pregnancy white matter microstructure magnetic resonance imaging (MRI) diffusion tensor imaging (DTI) anxiety Index. décimale : PER Périodiques Résumé : The prenatal period represents a critical time for brain growth and development. These rapid neurological advances render the fetus susceptible to various influences with life-long implications for mental health. Maternal distress signals are a dominant early life influence, contributing to birth outcomes and risk for offspring psychopathology. This prospective longitudinal study evaluated the association between prenatal maternal distress and infant white matter microstructure. Participants included a racially and socioeconomically diverse sample of 85 mother–infant dyads. Prenatal distress was assessed at 17 and 29 weeks’ gestational age (GA). Infant structural data were collected via diffusion tensor imaging (DTI) at 42–45 weeks’ postconceptional age. Findings demonstrated that higher prenatal maternal distress at 29 weeks’ GA was associated with increased fractional anisotropy, b = .283, t(64) = 2.319, p = .024, and with increased axial diffusivity, b = .254, t(64) = 2.067, p = .043, within the right anterior cingulate white matter tract. No other significant associations were found with prenatal distress exposure and tract fractional anisotropy or axial diffusivity at 29 weeks’ GA, or earlier in gestation. En ligne : http://dx.doi.org/10.1017/S0954579421000742 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457
in Development and Psychopathology > 33-5 (December 2021) . - p.1526-1538[article] Exposure to prenatal maternal distress and infant white matter neurodevelopment [Texte imprimé et/ou numérique] / Catherine H. DEMERS, Auteur ; Maria M. BAGONIS, Auteur ; Khalid AL-ALI, Auteur ; Sarah E. GARCIA, Auteur ; Martin A. STYNER, Auteur ; John H. GILMORE, Auteur ; M. Camille HOFFMAN, Auteur ; Benjamin L. HANKIN, Auteur ; Elysia Poggi DAVIS, Auteur . - p.1526-1538.
Langues : Anglais (eng)
in Development and Psychopathology > 33-5 (December 2021) . - p.1526-1538
Mots-clés : pregnancy white matter microstructure magnetic resonance imaging (MRI) diffusion tensor imaging (DTI) anxiety Index. décimale : PER Périodiques Résumé : The prenatal period represents a critical time for brain growth and development. These rapid neurological advances render the fetus susceptible to various influences with life-long implications for mental health. Maternal distress signals are a dominant early life influence, contributing to birth outcomes and risk for offspring psychopathology. This prospective longitudinal study evaluated the association between prenatal maternal distress and infant white matter microstructure. Participants included a racially and socioeconomically diverse sample of 85 mother–infant dyads. Prenatal distress was assessed at 17 and 29 weeks’ gestational age (GA). Infant structural data were collected via diffusion tensor imaging (DTI) at 42–45 weeks’ postconceptional age. Findings demonstrated that higher prenatal maternal distress at 29 weeks’ GA was associated with increased fractional anisotropy, b = .283, t(64) = 2.319, p = .024, and with increased axial diffusivity, b = .254, t(64) = 2.067, p = .043, within the right anterior cingulate white matter tract. No other significant associations were found with prenatal distress exposure and tract fractional anisotropy or axial diffusivity at 29 weeks’ GA, or earlier in gestation. En ligne : http://dx.doi.org/10.1017/S0954579421000742 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457