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Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder / L. K. WINK in Journal of Autism and Developmental Disorders, 48-11 (November 2018)
[article]
Titre : Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : L. K. WINK, Auteur ; Ernest V. PEDAPATI, Auteur ; R. ADAMS, Auteur ; C. A. ERICKSON, Auteur ; K. A. PEDERSEN, Auteur ; E. M. MORROW, Auteur ; Desmond KAPLAN, Auteur ; M. SIEGEL, Auteur Article en page(s) : p.3711-3719 Langues : Anglais (eng) Mots-clés : Antipsychotics Autism Autism Spectrum Disorder Medication Psychiatric hospitalization Index. décimale : PER Périodiques Résumé : Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3153-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370
in Journal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3711-3719[article] Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / L. K. WINK, Auteur ; Ernest V. PEDAPATI, Auteur ; R. ADAMS, Auteur ; C. A. ERICKSON, Auteur ; K. A. PEDERSEN, Auteur ; E. M. MORROW, Auteur ; Desmond KAPLAN, Auteur ; M. SIEGEL, Auteur . - p.3711-3719.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3711-3719
Mots-clés : Antipsychotics Autism Autism Spectrum Disorder Medication Psychiatric hospitalization Index. décimale : PER Périodiques Résumé : Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3153-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 Parent Perspectives on Psychotropic Medication Use and Interactions With Prescribing Health Care Providers Among Adolescents and Adults With an Autism Spectrum Disorder / Johanna K. LAKE in Focus on Autism and Other Developmental Disabilities, 30-3 (September 2015)
[article]
Titre : Parent Perspectives on Psychotropic Medication Use and Interactions With Prescribing Health Care Providers Among Adolescents and Adults With an Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Johanna K. LAKE, Auteur ; Alexander MILOVANOV, Auteur ; Amanda SAWYER, Auteur ; Yona LUNSKY, Auteur Article en page(s) : p.165-173 Langues : Anglais (eng) Mots-clés : adults adolescents autism spectrum disorder support systems parents medication health care providers Index. décimale : PER Périodiques Résumé : Adolescents and young adults with an autism spectrum disorder (ASD) are often prescribed psychotropic medications to treat mental health and behavioral issues, and parents of these individuals play a crucial role in overseeing this care. Despite this, little is known about parents’ experiences managing and monitoring their child’s medication treatment, or their experience interacting with prescribing health care providers. To learn more about parents’ perspectives on psychotropic medication use in their adolescent or young adult with ASD, a focus group was conducted with seven mothers whose adolescent or adult child with ASD was prescribed one or more psychotropic medications. Results are summarized according to emergent themes including parent perception of child experience with medication, side effects, medication efficacy, medication monitoring, expertise issues, and service issues. Parents also provided medication recommendations, including a desire for health care providers with greater expertise in ASD, information on medication, and tools for medication monitoring. En ligne : http://dx.doi.org/10.1177/1088357614559215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=266
in Focus on Autism and Other Developmental Disabilities > 30-3 (September 2015) . - p.165-173[article] Parent Perspectives on Psychotropic Medication Use and Interactions With Prescribing Health Care Providers Among Adolescents and Adults With an Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Johanna K. LAKE, Auteur ; Alexander MILOVANOV, Auteur ; Amanda SAWYER, Auteur ; Yona LUNSKY, Auteur . - p.165-173.
Langues : Anglais (eng)
in Focus on Autism and Other Developmental Disabilities > 30-3 (September 2015) . - p.165-173
Mots-clés : adults adolescents autism spectrum disorder support systems parents medication health care providers Index. décimale : PER Périodiques Résumé : Adolescents and young adults with an autism spectrum disorder (ASD) are often prescribed psychotropic medications to treat mental health and behavioral issues, and parents of these individuals play a crucial role in overseeing this care. Despite this, little is known about parents’ experiences managing and monitoring their child’s medication treatment, or their experience interacting with prescribing health care providers. To learn more about parents’ perspectives on psychotropic medication use in their adolescent or young adult with ASD, a focus group was conducted with seven mothers whose adolescent or adult child with ASD was prescribed one or more psychotropic medications. Results are summarized according to emergent themes including parent perception of child experience with medication, side effects, medication efficacy, medication monitoring, expertise issues, and service issues. Parents also provided medication recommendations, including a desire for health care providers with greater expertise in ASD, information on medication, and tools for medication monitoring. En ligne : http://dx.doi.org/10.1177/1088357614559215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=266 Perceived helpfulness of depression treatments among young adults with autism / S. ZHENG in Autism Research, 14-7 (July 2021)
[article]
Titre : Perceived helpfulness of depression treatments among young adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : S. ZHENG, Auteur ; Julie LOUNDS TAYLOR, Auteur ; R. ADAMS, Auteur ; F. PEZZIMENTI, Auteur ; Somer L. BISHOP, Auteur Article en page(s) : p.1522-1528 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/complications/therapy Autistic Disorder Depression/complications/therapy Educational Status Female Humans Male Surveys and Questionnaires Young Adult depressive symptoms individual therapy measure medication treatment helpfulness Index. décimale : PER Périodiques Résumé : Currently available treatments for depression show limited effectiveness in adults with autism spectrum disorders (ASD) based on measures of symptom changes and clinician impressions. Perceived helpfulness is another metric that has been found to be useful for understanding treatment outcomes in the general population, but it has not yet been explored in adults with ASD. Thus, the current study collected online survey data to examine patient-perceived treatment helpfulness in a sample of 144 adults with ASD who reported that they were currently receiving community-based treatment for depression. Findings indicate that while there was variability in the levels of perceived helpfulness for both medication and individual therapy, most adults with ASD perceived treatment to be at least moderately helpful. Notably, adults with ASD reported having been in treatment for a prolonged duration (5 to 6?years). Ordinal logistic regression models showed that adults with more depressive symptoms perceived treatments to be less helpful (i.e., medications: odds ratio [OR] = 0.92, 95% confidence interval[CI] = 0.89-0.95; individual therapy: OR = 0.95, 95% CI = 0.92-0.99). Moreover, women perceived medication as more helpful than men (OR = 2.33, 95% CI = 1.13-4.82). Other individual (i.e., age, race, education level) and treatment (i.e., treatment length, concurrent treatment) characteristics were not significantly associated with perceived helpfulness. These findings suggest that future studies may want to use perceived helpfulness, in addition to traditionally used objective outcomes, to understand patients' treatment experience and evaluate depression treatments for adults with ASD. LAY SUMMARY: Adults with autism are much more likely to be depressed than those without autism; therefore, effective depression treatments are necessary to improve mental health outcomes in this group. This online survey study found that most adults with autism felt that the depression treatments they were receiving in the community (i.e., medication and individual therapy) were helpful. Females and those with fewer symptoms of depression felt treatments were more helpful compared with males and those with more symptoms of depression. Our findings suggest that when examining whether treatments for depression are effective, it may be important to measure adults' feelings about the helpfulness of the treatments in addition to measuring changes in symptoms of depression. En ligne : http://dx.doi.org/10.1002/aur.2515 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449
in Autism Research > 14-7 (July 2021) . - p.1522-1528[article] Perceived helpfulness of depression treatments among young adults with autism [Texte imprimé et/ou numérique] / S. ZHENG, Auteur ; Julie LOUNDS TAYLOR, Auteur ; R. ADAMS, Auteur ; F. PEZZIMENTI, Auteur ; Somer L. BISHOP, Auteur . - p.1522-1528.
Langues : Anglais (eng)
in Autism Research > 14-7 (July 2021) . - p.1522-1528
Mots-clés : Autism Spectrum Disorder/complications/therapy Autistic Disorder Depression/complications/therapy Educational Status Female Humans Male Surveys and Questionnaires Young Adult depressive symptoms individual therapy measure medication treatment helpfulness Index. décimale : PER Périodiques Résumé : Currently available treatments for depression show limited effectiveness in adults with autism spectrum disorders (ASD) based on measures of symptom changes and clinician impressions. Perceived helpfulness is another metric that has been found to be useful for understanding treatment outcomes in the general population, but it has not yet been explored in adults with ASD. Thus, the current study collected online survey data to examine patient-perceived treatment helpfulness in a sample of 144 adults with ASD who reported that they were currently receiving community-based treatment for depression. Findings indicate that while there was variability in the levels of perceived helpfulness for both medication and individual therapy, most adults with ASD perceived treatment to be at least moderately helpful. Notably, adults with ASD reported having been in treatment for a prolonged duration (5 to 6?years). Ordinal logistic regression models showed that adults with more depressive symptoms perceived treatments to be less helpful (i.e., medications: odds ratio [OR] = 0.92, 95% confidence interval[CI] = 0.89-0.95; individual therapy: OR = 0.95, 95% CI = 0.92-0.99). Moreover, women perceived medication as more helpful than men (OR = 2.33, 95% CI = 1.13-4.82). Other individual (i.e., age, race, education level) and treatment (i.e., treatment length, concurrent treatment) characteristics were not significantly associated with perceived helpfulness. These findings suggest that future studies may want to use perceived helpfulness, in addition to traditionally used objective outcomes, to understand patients' treatment experience and evaluate depression treatments for adults with ASD. LAY SUMMARY: Adults with autism are much more likely to be depressed than those without autism; therefore, effective depression treatments are necessary to improve mental health outcomes in this group. This online survey study found that most adults with autism felt that the depression treatments they were receiving in the community (i.e., medication and individual therapy) were helpful. Females and those with fewer symptoms of depression felt treatments were more helpful compared with males and those with more symptoms of depression. Our findings suggest that when examining whether treatments for depression are effective, it may be important to measure adults' feelings about the helpfulness of the treatments in addition to measuring changes in symptoms of depression. En ligne : http://dx.doi.org/10.1002/aur.2515 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 Polypharmacy profiles and predictors among adults with autism spectrum disorders / Johanna K. LAKE in Research in Autism Spectrum Disorders, 6-3 (July-September 2012)
[article]
Titre : Polypharmacy profiles and predictors among adults with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Johanna K. LAKE, Auteur ; Robert BALOGH, Auteur ; Yona LUNSKY, Auteur Année de publication : 2012 Article en page(s) : p.1142-1149 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Medication Polypharmacy Psychotropic medication Index. décimale : PER Périodiques Résumé : Pharmacological interventions are frequently used to treat commonly associated mental health and behavioural issues in individuals with autism spectrum disorders (ASD). Despite high rates of psychotropic drug use documented in children with ASD, very few studies have examined medication profiles, side effects, and rates of polypharmacy in adolescents and adults with ASD. To address this, we examined medication profiles and predictors of polypharmacy among 142 adults with ASD who had experienced a psychiatric crisis. Of the 142 adults sampled, 91 (64.1%) were prescribed at least 1 psychotropic medication and 41 (28.9%) were taking 3 or more psychotropic medications. Variables associated with and predictive of polypharmacy included history of aggression, residence, and psychiatric support. Adults with ASD are a highly medicated population and polypharmacy is a significant concern in this vulnerable group of individuals. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.03.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154
in Research in Autism Spectrum Disorders > 6-3 (July-September 2012) . - p.1142-1149[article] Polypharmacy profiles and predictors among adults with autism spectrum disorders [Texte imprimé et/ou numérique] / Johanna K. LAKE, Auteur ; Robert BALOGH, Auteur ; Yona LUNSKY, Auteur . - 2012 . - p.1142-1149.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 6-3 (July-September 2012) . - p.1142-1149
Mots-clés : Autism spectrum disorder Medication Polypharmacy Psychotropic medication Index. décimale : PER Périodiques Résumé : Pharmacological interventions are frequently used to treat commonly associated mental health and behavioural issues in individuals with autism spectrum disorders (ASD). Despite high rates of psychotropic drug use documented in children with ASD, very few studies have examined medication profiles, side effects, and rates of polypharmacy in adolescents and adults with ASD. To address this, we examined medication profiles and predictors of polypharmacy among 142 adults with ASD who had experienced a psychiatric crisis. Of the 142 adults sampled, 91 (64.1%) were prescribed at least 1 psychotropic medication and 41 (28.9%) were taking 3 or more psychotropic medications. Variables associated with and predictive of polypharmacy included history of aggression, residence, and psychiatric support. Adults with ASD are a highly medicated population and polypharmacy is a significant concern in this vulnerable group of individuals. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.03.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents / Samuele CORTESE in Journal of Child Psychology and Psychiatry, 54-3 (March 2013)
[article]
Titre : Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Samuele CORTESE, Auteur ; Martin HOLTMANN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Jan K. BUITELAAR, Auteur ; David R. COGHILL, Auteur ; Marina DANCKAERTS, Auteur ; Ralf W. DITTMANN, Auteur ; John GRAHAM, Auteur ; Eric TAYLOR, Auteur ; Joseph A. SERGEANT, Auteur ; Adhd Guidelines Group ON BEHALF OF THE EUROPEAN, Auteur Article en page(s) : p.227-246 Mots-clés : ADHD medication adverse events management recommendations European Index. décimale : PER Périodiques Résumé : Background: Medication is an important element of therapeutic strategies for ADHD. While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs. The aim of this review is to provide evidence- and expert-based guidance concerning the management of (AEs) with medications for ADHD. Methods: For ease of use by practitioners and clinicians, the article is organized in a simple question and answer format regarding the prevalence and management of the most common AEs. Answers were based on empirical evidence from studies (preferably meta-analyses or systematic reviews) retrieved in PubMed, Ovid, EMBASE and Web of Knowledge through 30 June 2012. When no empirical evidence was available, expert consensus of the members of the European ADHD Guidelines Group is provided. The evidence-level of the management recommendations was based on the SIGN grading system. Results: The review covers monitoring and management strategies of loss of appetite and growth delay, cardiovascular risks, sleep disturbance, tics, substance misuse/abuse, seizures, suicidal thoughts/behaviours and psychotic symptoms. Conclusion: Most AEs during treatment with drugs for ADHD are manageable and most of the times it is not necessary to stop medication, so that patients with ADHD may continue to benefit from the effectiveness of pharmacological treatment. En ligne : http://dx.doi.org/10.1111/jcpp.12036 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191
in Journal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.227-246[article] Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents [Texte imprimé et/ou numérique] / Samuele CORTESE, Auteur ; Martin HOLTMANN, Auteur ; Tobias BANASCHEWSKI, Auteur ; Jan K. BUITELAAR, Auteur ; David R. COGHILL, Auteur ; Marina DANCKAERTS, Auteur ; Ralf W. DITTMANN, Auteur ; John GRAHAM, Auteur ; Eric TAYLOR, Auteur ; Joseph A. SERGEANT, Auteur ; Adhd Guidelines Group ON BEHALF OF THE EUROPEAN, Auteur . - p.227-246.
in Journal of Child Psychology and Psychiatry > 54-3 (March 2013) . - p.227-246
Mots-clés : ADHD medication adverse events management recommendations European Index. décimale : PER Périodiques Résumé : Background: Medication is an important element of therapeutic strategies for ADHD. While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs. The aim of this review is to provide evidence- and expert-based guidance concerning the management of (AEs) with medications for ADHD. Methods: For ease of use by practitioners and clinicians, the article is organized in a simple question and answer format regarding the prevalence and management of the most common AEs. Answers were based on empirical evidence from studies (preferably meta-analyses or systematic reviews) retrieved in PubMed, Ovid, EMBASE and Web of Knowledge through 30 June 2012. When no empirical evidence was available, expert consensus of the members of the European ADHD Guidelines Group is provided. The evidence-level of the management recommendations was based on the SIGN grading system. Results: The review covers monitoring and management strategies of loss of appetite and growth delay, cardiovascular risks, sleep disturbance, tics, substance misuse/abuse, seizures, suicidal thoughts/behaviours and psychotic symptoms. Conclusion: Most AEs during treatment with drugs for ADHD are manageable and most of the times it is not necessary to stop medication, so that patients with ADHD may continue to benefit from the effectiveness of pharmacological treatment. En ligne : http://dx.doi.org/10.1111/jcpp.12036 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=191 Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder / Robert T. SCHULTZ in Autism - Open Access, 6-2 ([01/03/2016])
PermalinkAnnual Research Review: New frontiers in developmental neuropharmacology: can long-term therapeutic effects of drugs be optimized through carefully timed early intervention? / Susan L. ANDERSEN in Journal of Child Psychology and Psychiatry, 52-4 (April 2011)
PermalinkDimension médicale des troubles comportementaux / E. PEETERS in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 86 (Mai 2006)
PermalinkEfficacy and safety of memantine in children with autism spectrum disorder: Results from three phase 2 multicenter studies / A. Y. HARDAN in Autism, 23-8 (November 2019)
PermalinkSelf-reported parkinsonism features in older autistic adults: A descriptive study / H. M. GEURTS in Autism, 26-1 (January 2022)
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