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Faire une suggestionCategorizing the cries of infants with ASD versus typically developing infants: A study of adult accuracy and reaction time / Marc H. BORNSTEIN in Research in Autism Spectrum Disorders, 31 (November 2016)
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[article]
Titre : Categorizing the cries of infants with ASD versus typically developing infants: A study of adult accuracy and reaction time Type de document : texte imprimé Auteurs : Marc H. BORNSTEIN, Auteur ; K. COSTLOW, Auteur ; A. TRUZZI, Auteur ; Gianluca ESPOSITO, Auteur Article en page(s) : p.66-72 Langues : Anglais (eng) Mots-clés : Cry Infancy Autism spectrum disorder Typical development Vocalizations Reaction time Index. décimale : PER Périodiques Résumé : AbstractBackground The cries of children with Autism Spectrum Disorder (ASD) contain atypical acoustic features. The cries of typically developing infants elicit automatic adult responses, but little is known about how the atypical cries of children with ASD affect the speed with which adults process them. Method. We used a reaction time (RT) categorical task to analyze adults’ categorization of typically developing cries, atypical (ASD) cries, mammalian animal cries, and environmental noise control sounds. 40 nonparent women (M age = 27 years) were instructed to categorize acoustic stimuli as human infant cries or non-human sounds as quickly as possible. Results. The RTs for correctly categorizing the cries of children with ASD (M = 831 ms, SEM = 27) were slower than RTs for typically developing child cries (M = 680 ms, SEM = 6) as well as mammalian animal cries (801 ms, SEM = 11) and environmental noise control sounds (M = 692 ms, SEM = 10). Conclusions. This difference may reflect difficulties in adults’ perceiving and processing atypical cries of children with ASD, and the findings may have implications for the parent-child relationship and for the quality of care children with ASD receive. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295
in Research in Autism Spectrum Disorders > 31 (November 2016) . - p.66-72[article] Categorizing the cries of infants with ASD versus typically developing infants: A study of adult accuracy and reaction time [texte imprimé] / Marc H. BORNSTEIN, Auteur ; K. COSTLOW, Auteur ; A. TRUZZI, Auteur ; Gianluca ESPOSITO, Auteur . - p.66-72.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 31 (November 2016) . - p.66-72
Mots-clés : Cry Infancy Autism spectrum disorder Typical development Vocalizations Reaction time Index. décimale : PER Périodiques Résumé : AbstractBackground The cries of children with Autism Spectrum Disorder (ASD) contain atypical acoustic features. The cries of typically developing infants elicit automatic adult responses, but little is known about how the atypical cries of children with ASD affect the speed with which adults process them. Method. We used a reaction time (RT) categorical task to analyze adults’ categorization of typically developing cries, atypical (ASD) cries, mammalian animal cries, and environmental noise control sounds. 40 nonparent women (M age = 27 years) were instructed to categorize acoustic stimuli as human infant cries or non-human sounds as quickly as possible. Results. The RTs for correctly categorizing the cries of children with ASD (M = 831 ms, SEM = 27) were slower than RTs for typically developing child cries (M = 680 ms, SEM = 6) as well as mammalian animal cries (801 ms, SEM = 11) and environmental noise control sounds (M = 692 ms, SEM = 10). Conclusions. This difference may reflect difficulties in adults’ perceiving and processing atypical cries of children with ASD, and the findings may have implications for the parent-child relationship and for the quality of care children with ASD receive. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.08.001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295 Focused attention in late-diagnosed adults with autism spectrum disorder – A matter of reaction time? / Stefanie GROBA in Research in Autism, 131 (March 2026)
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Titre : Focused attention in late-diagnosed adults with autism spectrum disorder – A matter of reaction time? Type de document : texte imprimé Auteurs : Stefanie GROBA, Auteur ; Alexandra KNIESE, Auteur ; Stephanie DEEST-GAUBATZ, Auteur ; Johanna SEIFERT, Auteur ; Christian EBERLEIN, Auteur ; Stefan BLEICH, Auteur ; Maximilian DEEST, Auteur ; Helge FRIELING, Auteur ; Jelte WIETING, Auteur Article en page(s) : 202806 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Adult Focused attention Test Battery for Attention Performance (TAP) Working memory Reaction time Index. décimale : PER Périodiques Résumé : Diagnosing autism spectrum disorder (ASD) in adulthood is challenging due to its heterogeneity, high prevalence of co-occurring psychiatric disorders, and lack of established diagnostic measures. As deficits in basic attentional functions, in addition to core behavioral characteristics, have been associated with ASD in children and adolescents, this study examined focused attentional profiles in adults with late-diagnosed ASD without intellectual disability and compared them to a matched non-autistic control group (NC) using the Test Battery for Attention Performance (TAP). The study included 37 individuals with ASD (17 females, 20 males; mean age 33.57 ± 10.2 y) and 34 NC (18 females, 16 males; 34.0 ± 11.02 y). While qualitative performance indicators did not differ significantly, adults with ASD consistently showed longer reaction times on most TAP tests reflecting focused attention. Controlling for co-occurring depression and attention deficit hyperactivity disorder, reaction time on the TAP working memory task was found to be a potential discriminator between ASD and NC, albeit with modest discriminative power. In contrast to findings in children and adolescents with ASD, adults with ASD showed temporal rather than qualitative performance deficits, suggesting a possible speed-accuracy trade-off. These findings contribute to the understanding of attentional mechanisms in adults with ASD by highlighting the importance of temporal processing in attentional tasks and suggest implications for diagnostic assessment, intervention, and remediation. En ligne : https://doi.org/10.1016/j.reia.2026.202806 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=581
in Research in Autism > 131 (March 2026) . - 202806[article] Focused attention in late-diagnosed adults with autism spectrum disorder – A matter of reaction time? [texte imprimé] / Stefanie GROBA, Auteur ; Alexandra KNIESE, Auteur ; Stephanie DEEST-GAUBATZ, Auteur ; Johanna SEIFERT, Auteur ; Christian EBERLEIN, Auteur ; Stefan BLEICH, Auteur ; Maximilian DEEST, Auteur ; Helge FRIELING, Auteur ; Jelte WIETING, Auteur . - 202806.
Langues : Anglais (eng)
in Research in Autism > 131 (March 2026) . - 202806
Mots-clés : Autism spectrum disorder Adult Focused attention Test Battery for Attention Performance (TAP) Working memory Reaction time Index. décimale : PER Périodiques Résumé : Diagnosing autism spectrum disorder (ASD) in adulthood is challenging due to its heterogeneity, high prevalence of co-occurring psychiatric disorders, and lack of established diagnostic measures. As deficits in basic attentional functions, in addition to core behavioral characteristics, have been associated with ASD in children and adolescents, this study examined focused attentional profiles in adults with late-diagnosed ASD without intellectual disability and compared them to a matched non-autistic control group (NC) using the Test Battery for Attention Performance (TAP). The study included 37 individuals with ASD (17 females, 20 males; mean age 33.57 ± 10.2 y) and 34 NC (18 females, 16 males; 34.0 ± 11.02 y). While qualitative performance indicators did not differ significantly, adults with ASD consistently showed longer reaction times on most TAP tests reflecting focused attention. Controlling for co-occurring depression and attention deficit hyperactivity disorder, reaction time on the TAP working memory task was found to be a potential discriminator between ASD and NC, albeit with modest discriminative power. In contrast to findings in children and adolescents with ASD, adults with ASD showed temporal rather than qualitative performance deficits, suggesting a possible speed-accuracy trade-off. These findings contribute to the understanding of attentional mechanisms in adults with ASD by highlighting the importance of temporal processing in attentional tasks and suggest implications for diagnostic assessment, intervention, and remediation. En ligne : https://doi.org/10.1016/j.reia.2026.202806 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=581 Increased reaction time variability in attention-deficit hyperactivity disorder as a response-related phenomenon: evidence from single-trial event-related potentials / Christopher W.N. SAVILLE in Journal of Child Psychology and Psychiatry, 56-7 (July 2015)
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Titre : Increased reaction time variability in attention-deficit hyperactivity disorder as a response-related phenomenon: evidence from single-trial event-related potentials Type de document : texte imprimé Auteurs : Christopher W.N. SAVILLE, Auteur ; Bernd FEIGE, Auteur ; Christian KLUCKERT, Auteur ; Stephan BENDER, Auteur ; Monica BISCALDI, Auteur ; Andrea BERGER, Auteur ; Christian FLEISCHHAKER, Auteur ; Klaus HENIGHAUSEN, Auteur ; Christoph KLEIN, Auteur Article en page(s) : p.801-813 Langues : Anglais (eng) Mots-clés : ADHD EEG reaction time working memory event-related potential Index. décimale : PER Périodiques Résumé : Background Increased intra-subject variability (ISV) in reaction times (RTs) is a promising endophenotype for attention-deficit hyperactivity disorder (ADHD) and among the most robust hallmarks of the disorder. ISV has been assumed to represent an attentional deficit, either reflecting lapses in attention or increased neural noise. Here, we use an innovative single-trial event-related potential approach to assess whether the increased ISV associated with ADHD is indeed attributable to attention, or whether it is related to response-related processing. Methods We measured electroencephalographic responses to working memory oddball tasks in patients with ADHD (N = 20, aged 11.3 ± 1.1) and healthy controls (N = 25, aged 11.7 ± 1.1), and analysed these data with a recently developed method of single-trial event-related potential analysis. Estimates of component latency variability were computed for the stimulus-locked and response-locked forms of the P3b and the lateralised readiness potential (LRP). Results ADHD patients showed significantly increased ISV in behavioural ISV. This increased ISV was paralleled by an increase in variability in response-locked event-related potential latencies, while variability in stimulus-locked latencies was equivalent between groups. This result held across the P3b and LRP. Latency of all components predicted RTs on a single-trial basis, confirming that all were relevant for speed of processing. Conclusions These data suggest that the increased ISV found in ADHD could be associated with response-end, rather than stimulus-end processes, in contrast to prevailing conceptions about the endophenotype. This mental chronometric approach may also be useful for exploring whether the existing lack of specificity of ISV to particular psychiatric conditions can be improved upon. En ligne : http://dx.doi.org/10.1111/jcpp.12348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.801-813[article] Increased reaction time variability in attention-deficit hyperactivity disorder as a response-related phenomenon: evidence from single-trial event-related potentials [texte imprimé] / Christopher W.N. SAVILLE, Auteur ; Bernd FEIGE, Auteur ; Christian KLUCKERT, Auteur ; Stephan BENDER, Auteur ; Monica BISCALDI, Auteur ; Andrea BERGER, Auteur ; Christian FLEISCHHAKER, Auteur ; Klaus HENIGHAUSEN, Auteur ; Christoph KLEIN, Auteur . - p.801-813.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.801-813
Mots-clés : ADHD EEG reaction time working memory event-related potential Index. décimale : PER Périodiques Résumé : Background Increased intra-subject variability (ISV) in reaction times (RTs) is a promising endophenotype for attention-deficit hyperactivity disorder (ADHD) and among the most robust hallmarks of the disorder. ISV has been assumed to represent an attentional deficit, either reflecting lapses in attention or increased neural noise. Here, we use an innovative single-trial event-related potential approach to assess whether the increased ISV associated with ADHD is indeed attributable to attention, or whether it is related to response-related processing. Methods We measured electroencephalographic responses to working memory oddball tasks in patients with ADHD (N = 20, aged 11.3 ± 1.1) and healthy controls (N = 25, aged 11.7 ± 1.1), and analysed these data with a recently developed method of single-trial event-related potential analysis. Estimates of component latency variability were computed for the stimulus-locked and response-locked forms of the P3b and the lateralised readiness potential (LRP). Results ADHD patients showed significantly increased ISV in behavioural ISV. This increased ISV was paralleled by an increase in variability in response-locked event-related potential latencies, while variability in stimulus-locked latencies was equivalent between groups. This result held across the P3b and LRP. Latency of all components predicted RTs on a single-trial basis, confirming that all were relevant for speed of processing. Conclusions These data suggest that the increased ISV found in ADHD could be associated with response-end, rather than stimulus-end processes, in contrast to prevailing conceptions about the endophenotype. This mental chronometric approach may also be useful for exploring whether the existing lack of specificity of ISV to particular psychiatric conditions can be improved upon. En ligne : http://dx.doi.org/10.1111/jcpp.12348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder / Michael SACHSE in Journal of Autism and Developmental Disorders, 43-5 (May 2013)
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Titre : Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Michael SACHSE, Auteur ; Sabine SCHLITT, Auteur ; Daniela HAINZ, Auteur ; Angela CIARAMIDARO, Auteur ; Shella SCHIRMAN, Auteur ; Henrik WALTER, Auteur ; Fritz POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Christine M. FREITAG, Auteur Article en page(s) : p.1222-1235 Langues : Anglais (eng) Mots-clés : Autism Executive functions Reaction time Movement time Information processing CANTAB Index. décimale : PER Périodiques Résumé : This study broadly examines executive (EF) and visuo-motor function in 30 adolescent and adult individuals with high-functioning autism spectrum disorder (ASD) in comparison to 28 controls matched for age, gender, and IQ. ASD individuals showed impaired spatial working memory, whereas planning, cognitive flexibility, and inhibition were spared. Pure movement execution during visuo-motor information processing also was intact. In contrast, execution time of reading, naming, and of visuo-motor information processing tasks including a choice component was increased in the ASD group. Results of this study are in line with previous studies reporting only minimal EF difficulties in older individuals with ASD when assessed by computerized tasks. The finding of impaired visuo-motor information processing should be accounted for in further neuropsychological studies in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1668-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1222-1235[article] Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder [texte imprimé] / Michael SACHSE, Auteur ; Sabine SCHLITT, Auteur ; Daniela HAINZ, Auteur ; Angela CIARAMIDARO, Auteur ; Shella SCHIRMAN, Auteur ; Henrik WALTER, Auteur ; Fritz POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Christine M. FREITAG, Auteur . - p.1222-1235.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1222-1235
Mots-clés : Autism Executive functions Reaction time Movement time Information processing CANTAB Index. décimale : PER Périodiques Résumé : This study broadly examines executive (EF) and visuo-motor function in 30 adolescent and adult individuals with high-functioning autism spectrum disorder (ASD) in comparison to 28 controls matched for age, gender, and IQ. ASD individuals showed impaired spatial working memory, whereas planning, cognitive flexibility, and inhibition were spared. Pure movement execution during visuo-motor information processing also was intact. In contrast, execution time of reading, naming, and of visuo-motor information processing tasks including a choice component was increased in the ASD group. Results of this study are in line with previous studies reporting only minimal EF difficulties in older individuals with ASD when assessed by computerized tasks. The finding of impaired visuo-motor information processing should be accounted for in further neuropsychological studies in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1668-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195 Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference / Rebecca H.C. NORRIS in Molecular Autism, 10 (2019)
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Titre : Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference Type de document : texte imprimé Auteurs : Rebecca H.C. NORRIS, Auteur ; Leonid CHURILOV, Auteur ; Anthony J. HANNAN, Auteur ; Jess NITHIANANTHARAJAH, Auteur Article en page(s) : 42 p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Perseveration Processing speed Reaction time Synapse Index. décimale : PER Périodiques Résumé : Cognitive dysfunction including disrupted behavioral flexibility is central to neurodevelopmental disorders such as Autism Spectrum Disorder (ASD). A cognitive measure that assesses relational memory, and the ability to flexibly assimilate and transfer learned information is transitive inference. Transitive inference is highly conserved across vertebrates and disrupted in cognitive disorders. Here, we examined how mutations in the synaptic cell-adhesion molecule neuroligin-3 (Nlgn3) that have been documented in ASD impact relational memory and behavioral flexibility. We first refined a rodent touchscreen assay to measure visual transitive inference, then assessed two mouse models of Nlgn3 dysfunction (Nlgn3 (-/y) and Nlgn3 (R451C)). Deep analysis of touchscreen behavioral data at a trial level established we could measure trajectories in flexible responding and changes in processing speed as cognitive load increased. We show that gene mutations in Nlgn3 do not disrupt relational memory, but significantly impact flexible responding. Our study presents the first analysis of reaction times in a rodent transitive inference test, highlighting response latencies from the touchscreen system are useful indicators of processing demands or decision-making processes. These findings expand our understanding of how dysfunction of key components of synaptic signaling complexes impact distinct cognitive processes disrupted in neurodevelopmental disorders, and advance our approaches for dissecting rodent behavioral assays to provide greater insights into clinically relevant cognitive symptoms. En ligne : http://dx.doi.org/10.1186/s13229-019-0292-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414
in Molecular Autism > 10 (2019) . - 42 p.[article] Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference [texte imprimé] / Rebecca H.C. NORRIS, Auteur ; Leonid CHURILOV, Auteur ; Anthony J. HANNAN, Auteur ; Jess NITHIANANTHARAJAH, Auteur . - 42 p.
Langues : Anglais (eng)
in Molecular Autism > 10 (2019) . - 42 p.
Mots-clés : Autism spectrum disorder Perseveration Processing speed Reaction time Synapse Index. décimale : PER Périodiques Résumé : Cognitive dysfunction including disrupted behavioral flexibility is central to neurodevelopmental disorders such as Autism Spectrum Disorder (ASD). A cognitive measure that assesses relational memory, and the ability to flexibly assimilate and transfer learned information is transitive inference. Transitive inference is highly conserved across vertebrates and disrupted in cognitive disorders. Here, we examined how mutations in the synaptic cell-adhesion molecule neuroligin-3 (Nlgn3) that have been documented in ASD impact relational memory and behavioral flexibility. We first refined a rodent touchscreen assay to measure visual transitive inference, then assessed two mouse models of Nlgn3 dysfunction (Nlgn3 (-/y) and Nlgn3 (R451C)). Deep analysis of touchscreen behavioral data at a trial level established we could measure trajectories in flexible responding and changes in processing speed as cognitive load increased. We show that gene mutations in Nlgn3 do not disrupt relational memory, but significantly impact flexible responding. Our study presents the first analysis of reaction times in a rodent transitive inference test, highlighting response latencies from the touchscreen system are useful indicators of processing demands or decision-making processes. These findings expand our understanding of how dysfunction of key components of synaptic signaling complexes impact distinct cognitive processes disrupted in neurodevelopmental disorders, and advance our approaches for dissecting rodent behavioral assays to provide greater insights into clinically relevant cognitive symptoms. En ligne : http://dx.doi.org/10.1186/s13229-019-0292-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 Temporal preparation in adults with autistic spectrum disorder: The variable foreperiod effect / Giovanna GIRARDI in Autism Research, 14-11 (November 2021)
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PermalinkVariability in post-error behavioral adjustment is associated with functional abnormalities in the temporal cortex in children with ADHD / Simona SPINELLI in Journal of Child Psychology and Psychiatry, 52-7 (July 2011)
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PermalinkAcquisition and Use of 'Priors' in Autism: Typical in Deciding Where to Look, Atypical in Deciding What Is There / Fredrik ALLENMARK in Journal of Autism and Developmental Disorders, 51-10 (October 2021)
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PermalinkDifficulties in Recognising Dynamic but not Static Emotional Body Movements in Autism Spectrum Disorder / Noemi MAZZONI in Journal of Autism and Developmental Disorders, 52-3 (March 2022)
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PermalinkA few of my favorite things: circumscribed interests in autism are not accompanied by increased attentional salience on a personalized selective attention task / Owen E. PARSONS in Molecular Autism, 8 (2017)
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