Pubmed (TDAH) du 19/05/26
1. Khoury SM, Gur A, Cohen A. Childhood Neglect in Individuals with ADHD and Related Neurodevelopmental Conditions: A Scoping Review. Clin Child Psychol Psychiatry;2026 (May 19):13591045261454520.
This scoping review investigates the relationship between childhood maltreatment, including physical, emotional, and sexual abuse, as well as neglect, and Attention-Deficit/Hyperactivity Disorder (ADHD) and Related Neurodevelopmental Outcomes. Following the PRISMA-ScR guidelines, a comprehensive literature search was conducted across five databases (PsycNET, Social Services Abstracts, ERIC, PubMed, and EBSCO) using a broad set of search terms related to ADHD, maltreatment, and childhood. The review included peer-reviewed articles published in English over the past 10 years, Studies published between January 2015 and February 2025 were included. The final database search was completed on March 1, 2025. The studies examined maltreatment in children with ADHD. Of the 854 initially identified studies, 12 met the inclusion criteria. Thematic analysis revealed three major findings: (1) various forms of maltreatment are strongly associated with increased risk and severity of ADHD symptoms; (2) mediating factors such as genetic predisposition, family dynamics, and emotional reactivity shape this relationship; and (3) maltreatment contributes to the persistence of ADHD symptoms and comorbid conditions into adulthood. These findings underscore the need for early trauma-informed interventions that address both biological and environmental influences on ADHD development. Attention-Deficit/Hyperactivity Disorder (ADHD) is a common condition in children and young people. It can affect attention, self-control, activity levels, and emotional regulation. At the same time, some children grow up in difficult or harmful environments, including experiences of emotional, physical, or sexual abuse, or different forms of neglect. This review looked at research published in the past ten years to better understand how childhood maltreatment and ADHD are connected. Across many studies, there was a clear and consistent link between experiences of maltreatment and ADHD. Children who experienced abuse or neglect were more likely to show symptoms of ADHD, and their symptoms were often more severe or lasted longer over time. However, the relationship appears to be complex. Some studies suggest that children with ADHD may also be more vulnerable to negative or harsh responses from caregivers because of behaviors such as impulsivity, hyperactivity, or emotional outbursts. This means the relationship between ADHD and maltreatment may go in both directions. Recent research also highlights the role of family stress, emotional difficulties, and biological stress responses in shaping how these experiences affect children over time. These findings suggest that when professionals assess a child for ADHD, it is important to also consider whether the child has experienced trauma or significant stress. eng
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2. Yi L, Yao H. Methodological provocations for detecting context-dependent ADHD-risk coupling: a commentary on Goueta et al. (2025). J Child Psychol Psychiatry;2026 (May 19)
Goueta et al. (Journal of Child Psychology and Psychiatry, 2025, 66, 1209) utilized a Random Intercept Cross-Lagged Panel Model (RI-CLPM) to investigate reciprocal links between ADHD symptoms and adolescent risky behavior. Their finding that stable between-person differences, rather than within-person fluctuations, primarily drive this association challenges common clinical assumptions. While commending their methodological rigor, this commentary proposes five refinements to better capture the dynamic ADHD-risk nexus. First, aggregating diverse risk behaviors may mask distinct symptom-coupled fluctuations, requiring multivariate models to separate impulsivity from social deviance. Second, relying exclusively on parent reports introduces bias; future studies should incorporate multi-informant designs, ecological momentary assessment (EMA), and passive sensing. Third, standard time metrics overlook critical developmental milestones; event-contingent sampling around salient transitions can address process non-stationarity. Fourth, integrating time-varying mediators, such as sleep and parental monitoring, can reveal precise windows of heightened risk for targeted interventions. Finally, dimensional scoring might obscure non-linear threshold effects and pharmacological impacts. By addressing behavioral heterogeneity, reporter variance, developmental contexts, and non-linearities, future research can clarify exactly when, for whom, and under what conditions ADHD symptom fluctuations forecast adolescent risk.
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3. Ziegler GC, Kürten K, Roshop K, Nieberler M, Warrings B, Kittel-Schneider S, Lesch KP, Herrmann MJ, Störk S, Deckert J. ADHD and metabolic syndrome: behavioral and weight-related pathways to cardiovascular risk. Eur Arch Psychiatry Clin Neurosci;2026 (May 19)
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) has been linked to obesity and type 2 diabetes, suggesting heightened cardiovascular risk. Whether adults with ADHD also show increased rates of metabolic syndrome (MetS), a cluster of central obesity, dyslipidemia, impaired glucose regulation, and hypertension, remains unclear. METHODS: We examined a young to middle-aged adult cohort of 83 patients and 82 healthy controls (HC). The primary objective was to test whether MetS (Joint Interim Statement criteria) was more prevalent in ADHD than in HC. To explore potential pathways linking ADHD with cardiovascular risk, we additionally assessed anthropometric indices, 24-h blood pressure (BP), heart rate (HR), and inflammatory markers (interleukin-6, C-reactive protein). Finally, we fitted a serial mediation model examining whether hyperactivity/impulsivity (HI), eating behavior, and body mass index (BMI) mediated the association between ADHD and BP. RESULTS: A higher proportion of ADHD patients fulfilled MetS criteria (OR 2.29). Adults with ADHD showed higher waist circumference, BMI, and overweight/obesity rates but did not differ in glucose and blood lipid levels. Non-stimulant medication and psychiatric comorbidity were more common among patients with MetS. Inflammatory markers were unrelated to ADHD. However, ADHD patients demonstrated slightly higher mean 24-h HR and nighttime systolic BP. The association between ADHD and nighttime systolic BP was mediated by obesity as a MetS constituent, and by HI and disordered eating as behavioral risk factors. CONCLUSION: Young to middle-aged adults with ADHD displayed increased MetS prevalence and subtle elevations in nighttime BP and HR, suggesting an early cardiovascular risk trajectory. Behavioral factors, particularly overeating and weight gain, and psychiatric comorbidity appear to contribute to this risk. These findings support early cardiovascular screening and weight-management interventions in adults with ADHD.
