Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur John L.R. RUBENSTEIN |
Documents disponibles écrits par cet auteur (2)
Faire une suggestion Affiner la recherche
Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders / John L.R. RUBENSTEIN in Journal of Child Psychology and Psychiatry, 52-4 (April 2011)
[article]
Titre : Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : John L.R. RUBENSTEIN, Auteur Année de publication : 2011 Article en page(s) : p.339-355 Langues : Anglais (eng) Mots-clés : Cortex development autism brain development fibroblast growth factor GABA Index. décimale : PER Périodiques Résumé : The cerebral cortex has a central role in cognitive and emotional processing. As such, understanding the mechanisms that govern its development and function will be central to understanding the bases of severe neuropsychiatric disorders, particularly those that first appear in childhood. In this review, I highlight recent progress in elucidating genetic, molecular and cellular mechanisms that control cortical development. I discuss basic aspects of cortical developmental anatomy, and mechanisms that regulate cortical size and area formation, with an emphasis on the roles of fibroblast growth factor (Fgf) signaling and specific transcription factors. I then examine how specific types of cortical excitatory projection neurons are generated, and how their axons grow along stereotyped pathways to their targets. Next, I address how cortical inhibitory (GABAergic) neurons are generated, and point out the role of these cells in controlling cortical plasticity and critical periods. The paper concludes with an examination of four possible developmental mechanisms that could contribute to some forms of neurodevelopmental disorders, such as autism. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02307.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119
in Journal of Child Psychology and Psychiatry > 52-4 (April 2011) . - p.339-355[article] Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders [Texte imprimé et/ou numérique] / John L.R. RUBENSTEIN, Auteur . - 2011 . - p.339-355.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-4 (April 2011) . - p.339-355
Mots-clés : Cortex development autism brain development fibroblast growth factor GABA Index. décimale : PER Périodiques Résumé : The cerebral cortex has a central role in cognitive and emotional processing. As such, understanding the mechanisms that govern its development and function will be central to understanding the bases of severe neuropsychiatric disorders, particularly those that first appear in childhood. In this review, I highlight recent progress in elucidating genetic, molecular and cellular mechanisms that control cortical development. I discuss basic aspects of cortical developmental anatomy, and mechanisms that regulate cortical size and area formation, with an emphasis on the roles of fibroblast growth factor (Fgf) signaling and specific transcription factors. I then examine how specific types of cortical excitatory projection neurons are generated, and how their axons grow along stereotyped pathways to their targets. Next, I address how cortical inhibitory (GABAergic) neurons are generated, and point out the role of these cells in controlling cortical plasticity and critical periods. The paper concludes with an examination of four possible developmental mechanisms that could contribute to some forms of neurodevelopmental disorders, such as autism. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02307.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 Developmental Neurobiology of Autism Spectrum Disorders / John L.R. RUBENSTEIN
Titre : Developmental Neurobiology of Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : John L.R. RUBENSTEIN, Auteur Année de publication : 2011 Importance : p.527-538 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 Developmental Neurobiology of Autism Spectrum Disorders [Texte imprimé et/ou numérique] / John L.R. RUBENSTEIN, Auteur . - 2011 . - p.527-538.
Langues : Anglais (eng)
Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire