Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study / Tamara MAY in Journal of Autism and Developmental Disorders, 41-7 (July 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.837-847 Titre : Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study Type de document : Texte imprimé et/ou numérique Auteurs : Tamara MAY, Auteur ; Warrick J. BREWER, Auteur ; Nicole J. RINEHART, Auteur ; Peter G. ENTICOTT, Auteur ; Avril V. BRERETON, Auteur ; Bruce J. TONGE, Auteur Année de publication : 2011 Article en page(s) : p.837-847 Langues : Anglais (eng) Mots-clés : High-functioning autism  Asperger’s disorder  Olfactory identification  UPSIT Index. décimale : PER Périodiques Résumé : Key theories of autism implicate orbitofrontal cortex (OFC) compromise, while olfactory identification (OI) deficits are associated with OFC dysfunction. This study aimed to complete a 5-year follow-up of children with high-functioning autism (HFA) who previously lacked the normal age-OI association; and compare unirhinal-OI in children with HFA, Asperger’s disorder (ASP), and controls. While both HFA and controls had improved birhinal-OI at follow-up, reduced OI in some HFA participants suggested OFC deterioration and heterogeneous OFC development. Unirhinal-OI was impaired in HFA but not ASP relative to controls, suggesting orbitofrontal compromise in HFA but integrity in ASP. Differing IQ-OI relationships existed between HFA and ASP. Findings support the hypothesis of separate neurobiological underpinnings in ASP and HFA, specifically differential orbitofrontal functioning. En ligne : http://dx.doi.org/10.1007/s10803-010-1101-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130 [article] Differential Olfactory Identification in Children with Autism and Asperger’s Disorder: A Comparative and Longitudinal Study [Texte imprimé et/ou numérique] / Tamara MAY, Auteur ; Warrick J. BREWER, Auteur ; Nicole J. RINEHART, Auteur ; Peter G. ENTICOTT, Auteur ; Avril V. BRERETON, Auteur ; Bruce J. TONGE, Auteur . - 2011 . - p.837-847. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.837-847 Mots-clés : High-functioning autism  Asperger’s disorder  Olfactory identification  UPSIT Index. décimale : PER Périodiques Résumé : Key theories of autism implicate orbitofrontal cortex (OFC) compromise, while olfactory identification (OI) deficits are associated with OFC dysfunction. This study aimed to complete a 5-year follow-up of children with high-functioning autism (HFA) who previously lacked the normal age-OI association; and compare unirhinal-OI in children with HFA, Asperger’s disorder (ASP), and controls. While both HFA and controls had improved birhinal-OI at follow-up, reduced OI in some HFA participants suggested OFC deterioration and heterogeneous OFC development. Unirhinal-OI was impaired in HFA but not ASP relative to controls, suggesting orbitofrontal compromise in HFA but integrity in ASP. Differing IQ-OI relationships existed between HFA and ASP. Findings support the hypothesis of separate neurobiological underpinnings in ASP and HFA, specifically differential orbitofrontal functioning. En ligne : http://dx.doi.org/10.1007/s10803-010-1101-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130

Dissociation of age and ability on a visual analogue of the University of Pennsylvania Smell Identification Test in children with autism / Warrick J. BREWER in Research in Autism Spectrum Disorders, 2-4 (October 2008)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 2-4 (October 2008) . - p.612-620 Titre : Dissociation of age and ability on a visual analogue of the University of Pennsylvania Smell Identification Test in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Warrick J. BREWER, Auteur ; Bruce J. TONGE, Auteur ; Avril V. BRERETON, Auteur Année de publication : 2008 Article en page(s) : p.612-620 Langues : Anglais (eng) Mots-clés : Autism Olfactory-identification UPSIT Index. décimale : PER Périodiques Résumé : Early olfactory identification deficits have been associated with neurodevelopmental arrest of limbic-prefrontal networks. These same networks are implicated in development of autistic-spectrum disorders. We aimed to investigate olfactory identification ability in children with high functioning autism (HFA). Fifteen children with HFA (aged 5–9 years) and 15 age-, gender- and IQ-matched controls (CTL) were compared on their performance on a visual analogue of the University of Pennsylvania Smell Identification Test (UPSIT). The hypothesis that children with HFA would exhibit impaired olfactory identification ability was not supported. However, contrary to the relationship found in the CTLs, smell identification ability was negatively associated with age in HFA. The results suggest some disruption of normal developmental association between olfactory ability and age in HFA. The visual analogue of the UPSIT warrants further investigation to determine its validity and reliability in normal and other clinical populations. En ligne : http://dx.doi.org/10.1016/j.rasd.2008.01.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=608 [article] Dissociation of age and ability on a visual analogue of the University of Pennsylvania Smell Identification Test in children with autism [Texte imprimé et/ou numérique] / Warrick J. BREWER, Auteur ; Bruce J. TONGE, Auteur ; Avril V. BRERETON, Auteur . - 2008 . - p.612-620. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 2-4 (October 2008) . - p.612-620 Mots-clés : Autism Olfactory-identification UPSIT Index. décimale : PER Périodiques Résumé : Early olfactory identification deficits have been associated with neurodevelopmental arrest of limbic-prefrontal networks. These same networks are implicated in development of autistic-spectrum disorders. We aimed to investigate olfactory identification ability in children with high functioning autism (HFA). Fifteen children with HFA (aged 5–9 years) and 15 age-, gender- and IQ-matched controls (CTL) were compared on their performance on a visual analogue of the University of Pennsylvania Smell Identification Test (UPSIT). The hypothesis that children with HFA would exhibit impaired olfactory identification ability was not supported. However, contrary to the relationship found in the CTLs, smell identification ability was negatively associated with age in HFA. The results suggest some disruption of normal developmental association between olfactory ability and age in HFA. The visual analogue of the UPSIT warrants further investigation to determine its validity and reliability in normal and other clinical populations. En ligne : http://dx.doi.org/10.1016/j.rasd.2008.01.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=608

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