
Accueil
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h00-17h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Météo
A partir de cette page vous pouvez :
Retourner au premier écran avec les dernières notices... |
Détail de l'auteur
Auteur Andrew J. O. WHITEHOUSE
Documents disponibles écrits par cet auteur



Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder / Lisa M. UNWIN in Journal of Autism and Developmental Disorders, 47-7 (July 2017)
![]()
[article]
in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2108-2119
Titre : Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Lisa M. UNWIN, Auteur ; Ildiko BRUZ, Auteur ; Murray T. MAYBERY, Auteur ; Victoria REYNOLDS, Auteur ; Natalie CICCONE, Auteur ; Cheryl DISSANAYAKE, Auteur ; Martha HICKEY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.2108-2119 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Crying Infant siblings Acoustic properties Index. décimale : PER Périodiques Résumé : There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder (ASD) have an atypical pattern of cry, characterized by higher fundamental frequency and increased dysphonation. This prospective study collected multiple cry samples of 12-month old siblings of children with ASD (n?=?22, ‘high-risk’ group) and 12-month olds with no family history of ASD (n?=?27, ‘low risk’ group). While there was no difference between groups in the fundamental frequency or degree of phonation of the cry samples, the duration of each cry unit was significantly shorter in the high-risk siblings (p?.05). The six infant siblings who received a diagnosis of ASD at age two had amongst the shortest recorded cry durations. En ligne : https://doi.org/10.1007/s10803-017-3119-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3140 [article] Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder [texte imprimé] / Lisa M. UNWIN, Auteur ; Ildiko BRUZ, Auteur ; Murray T. MAYBERY, Auteur ; Victoria REYNOLDS, Auteur ; Natalie CICCONE, Auteur ; Cheryl DISSANAYAKE, Auteur ; Martha HICKEY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.2108-2119.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.2108-2119
Mots-clés : Autism spectrum disorders Crying Infant siblings Acoustic properties Index. décimale : PER Périodiques Résumé : There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder (ASD) have an atypical pattern of cry, characterized by higher fundamental frequency and increased dysphonation. This prospective study collected multiple cry samples of 12-month old siblings of children with ASD (n?=?22, ‘high-risk’ group) and 12-month olds with no family history of ASD (n?=?27, ‘low risk’ group). While there was no difference between groups in the fundamental frequency or degree of phonation of the cry samples, the duration of each cry unit was significantly shorter in the high-risk siblings (p?.05). The six infant siblings who received a diagnosis of ASD at age two had amongst the shortest recorded cry durations. En ligne : https://doi.org/10.1007/s10803-017-3119-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3140 Are there differences in the behavioural phenotypes of Autism Spectrum Disorder probands from simplex and multiplex families? / Lauren J. TAYLOR in Research in Autism Spectrum Disorders, 11 (March 2015)
![]()
[article]
in Research in Autism Spectrum Disorders > 11 (March 2015) . - p.56-62
Titre : Are there differences in the behavioural phenotypes of Autism Spectrum Disorder probands from simplex and multiplex families? Type de document : texte imprimé Auteurs : Lauren J. TAYLOR, Auteur ; Murray T. MAYBERY, Auteur ; John WRAY, Auteur ; David RAVINE, Auteur ; Anna HUNT, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.56-62 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder Behavioural phenotype Simplex and multiplex families Index. décimale : PER Périodiques Résumé : Recent research suggests that different genetic pathways may operate for families with one child affected with Autism Spectrum Disorder (simplex ASD), compared to families that have multiple affected children (multiplex ASD). In this study, we investigated possible differences in the behavioural phenotypes of probands from simplex and multiplex ASD families using parent-report and standardised behavioural measures. Participants were 59 probands from multiplex ASD families (28 families), who were each matched on chronological age and sex with two probands from simplex families. Probands from multiplex families had greater social impairment (measured using the Social Responsiveness Scale) and worse pragmatic language (on the Children's Communication Checklist-2) than probands from simplex families. However, the multiplex children had less severe symptoms than the simplex children on the ADOS-G, and a significantly higher proportion of multiplex children did not meet autism spectrum cut-offs on this measure. These findings indicate that there are behavioural differences in children with ASD from simplex and multiplex families. In addition, the results reveal an important discrepancy between parent-report and clinician observation of autistic-like characteristics in siblings of an affected child, which may have implications for the assessment and diagnosis of ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.003 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2607 [article] Are there differences in the behavioural phenotypes of Autism Spectrum Disorder probands from simplex and multiplex families? [texte imprimé] / Lauren J. TAYLOR, Auteur ; Murray T. MAYBERY, Auteur ; John WRAY, Auteur ; David RAVINE, Auteur ; Anna HUNT, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.56-62.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 11 (March 2015) . - p.56-62
Mots-clés : Autism Spectrum Disorder Behavioural phenotype Simplex and multiplex families Index. décimale : PER Périodiques Résumé : Recent research suggests that different genetic pathways may operate for families with one child affected with Autism Spectrum Disorder (simplex ASD), compared to families that have multiple affected children (multiplex ASD). In this study, we investigated possible differences in the behavioural phenotypes of probands from simplex and multiplex ASD families using parent-report and standardised behavioural measures. Participants were 59 probands from multiplex ASD families (28 families), who were each matched on chronological age and sex with two probands from simplex families. Probands from multiplex families had greater social impairment (measured using the Social Responsiveness Scale) and worse pragmatic language (on the Children's Communication Checklist-2) than probands from simplex families. However, the multiplex children had less severe symptoms than the simplex children on the ADOS-G, and a significantly higher proportion of multiplex children did not meet autism spectrum cut-offs on this measure. These findings indicate that there are behavioural differences in children with ASD from simplex and multiplex families. In addition, the results reveal an important discrepancy between parent-report and clinician observation of autistic-like characteristics in siblings of an affected child, which may have implications for the assessment and diagnosis of ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.12.003 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2607 Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder / Gail A. ALVARES in Autism Research, 10-1 (January 2017)
![]()
[article]
in Autism Research > 10-1 (January 2017) . - p.25-41
Titre : Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder Type de document : texte imprimé Auteurs : Gail A. ALVARES, Auteur ; Daniel S. QUINTANA, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.25-41 Langues : Anglais (eng) Mots-clés : oxytocin neuropeptide hormones nasal spray Index. décimale : PER Périodiques Résumé : Extensive research efforts in the last decade have been expended into understanding whether intranasal oxytocin may be an effective therapeutic in treating social communication impairments in individuals with autism spectrum disorder (ASD). After much hyped early findings, subsequent clinical trials of longer-term administration have yielded more conservative and mixed evidence. However, it is still unclear at this stage whether these more disappointing findings reflect a true null effect or are mitigated by methodological differences masking true effects. In this review, we comprehensively evaluate the rationale for oxytocin as a therapeutic, evaluating evidence from randomized controlled trials, case reports, and open-label studies of oxytocin administration in individuals with ASD. The evidence to date, including reviews of preregistered trials, suggests a number of critical considerations for the design and interpretation of research in this area. These include considering the choice of ASD outcome measures, dosing and nasal spray device issues, and participant selection. Despite these limitations in the field to date, there remains significant potential for oxytocin to ameliorate aspects of the persistent and debilitating social impairments in individuals with ASD. Given the considerable media hype around new treatments for ASD, as well as the needs of eager families, there is an urgent need for researchers to prioritise considering such factors when conducting well-designed and controlled studies to further advance this field. En ligne : http://dx.doi.org/10.1002/aur.1692 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3029 [article] Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder [texte imprimé] / Gail A. ALVARES, Auteur ; Daniel S. QUINTANA, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.25-41.
Langues : Anglais (eng)
in Autism Research > 10-1 (January 2017) . - p.25-41
Mots-clés : oxytocin neuropeptide hormones nasal spray Index. décimale : PER Périodiques Résumé : Extensive research efforts in the last decade have been expended into understanding whether intranasal oxytocin may be an effective therapeutic in treating social communication impairments in individuals with autism spectrum disorder (ASD). After much hyped early findings, subsequent clinical trials of longer-term administration have yielded more conservative and mixed evidence. However, it is still unclear at this stage whether these more disappointing findings reflect a true null effect or are mitigated by methodological differences masking true effects. In this review, we comprehensively evaluate the rationale for oxytocin as a therapeutic, evaluating evidence from randomized controlled trials, case reports, and open-label studies of oxytocin administration in individuals with ASD. The evidence to date, including reviews of preregistered trials, suggests a number of critical considerations for the design and interpretation of research in this area. These include considering the choice of ASD outcome measures, dosing and nasal spray device issues, and participant selection. Despite these limitations in the field to date, there remains significant potential for oxytocin to ameliorate aspects of the persistent and debilitating social impairments in individuals with ASD. Given the considerable media hype around new treatments for ASD, as well as the needs of eager families, there is an urgent need for researchers to prioritise considering such factors when conducting well-designed and controlled studies to further advance this field. En ligne : http://dx.doi.org/10.1002/aur.1692 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3029 Brief Report: An Exploratory Study of the Diagnostic Reliability for Autism Spectrum Disorder / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 47-5 (May 2017)
![]()
[article]
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1551-1558
Titre : Brief Report: An Exploratory Study of the Diagnostic Reliability for Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Lauren J. TAYLOR, Auteur ; Valsamma EAPEN, Auteur ; Murray MAYBERY, Auteur ; Sue MIDFORD, Auteur ; Jessica PAYNTER, Auteur ; Lyndsay QUARMBY, Auteur ; Timothy SMITH, Auteur ; Katrina WILLIAMS, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.1551-1558 Langues : Anglais (eng) Mots-clés : Diagnosis Reliability Index. décimale : PER Périodiques Résumé : Previous research shows inconsistency in clinician-assigned diagnoses of Autism Spectrum Disorder (ASD). We conducted an exploratory study that examined the concordance of diagnoses between a multidisciplinary assessment team and a range of independent clinicians throughout Australia. Nine video-taped Autism Diagnostic Observation Schedule (ADOS) assessments were collected from two Australian sites. Twenty-seven Australian health professionals each observed two video-recordings and rated the degree to which the individual met the DSM-5 criteria for ASD. There was 100% agreement on the diagnostic classification for only 3 of the 9 video clips (33%), with the remaining 6 clips (66%) reaching poor reliability. In addition, only 24% of the participating clinicians achieved ‘good’ or ‘excellent’ levels of agreement (Cohen’s kappa?>?0.6) with the original ASD assessment. These findings have implications for clinical guidelines for ASD assessments. En ligne : http://dx.doi.org/10.1007/s10803-017-3054-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3059 [article] Brief Report: An Exploratory Study of the Diagnostic Reliability for Autism Spectrum Disorder [texte imprimé] / Lauren J. TAYLOR, Auteur ; Valsamma EAPEN, Auteur ; Murray MAYBERY, Auteur ; Sue MIDFORD, Auteur ; Jessica PAYNTER, Auteur ; Lyndsay QUARMBY, Auteur ; Timothy SMITH, Auteur ; Katrina WILLIAMS, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.1551-1558.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1551-1558
Mots-clés : Diagnosis Reliability Index. décimale : PER Périodiques Résumé : Previous research shows inconsistency in clinician-assigned diagnoses of Autism Spectrum Disorder (ASD). We conducted an exploratory study that examined the concordance of diagnoses between a multidisciplinary assessment team and a range of independent clinicians throughout Australia. Nine video-taped Autism Diagnostic Observation Schedule (ADOS) assessments were collected from two Australian sites. Twenty-seven Australian health professionals each observed two video-recordings and rated the degree to which the individual met the DSM-5 criteria for ASD. There was 100% agreement on the diagnostic classification for only 3 of the 9 video clips (33%), with the remaining 6 clips (66%) reaching poor reliability. In addition, only 24% of the participating clinicians achieved ‘good’ or ‘excellent’ levels of agreement (Cohen’s kappa?>?0.6) with the original ASD assessment. These findings have implications for clinical guidelines for ASD assessments. En ligne : http://dx.doi.org/10.1007/s10803-017-3054-z Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3059 Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents? / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 43-12 (December 2013)
![]()
[article]
in Journal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2984-2989
Titre : Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents? Type de document : texte imprimé Auteurs : Lauren J. TAYLOR, Auteur ; Murray T. MAYBERY, Auteur ; John WRAY, Auteur ; David RAVINE, Auteur ; Anna HUNT, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.2984-2989 Langues : Anglais (eng) Mots-clés : Heritable language phenotype Broader autism phenotype Communication impairment Index. décimale : PER Périodiques Résumé : Extensive empirical evidence indicates that the lesser variant of Autism Spectrum Disorders (ASD) involves a communication impairment that is similar to, but milder than, the deficit in clinical ASD. This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband communication difficulties. ASD probands with at least one BAP parent (identified using the Autism Spectrum Quotient) had greater structural and pragmatic language difficulties (assessed using the Children’s Communication Checklist-2) than ASD probands with no BAP parent. This finding provides support for the position that genetic liability for ASD is associated with increased communication difficulties across structural and pragmatic domains. En ligne : http://dx.doi.org/10.1007/s10803-013-1838-3 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2187 [article] Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents? [texte imprimé] / Lauren J. TAYLOR, Auteur ; Murray T. MAYBERY, Auteur ; John WRAY, Auteur ; David RAVINE, Auteur ; Anna HUNT, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.2984-2989.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2984-2989
Mots-clés : Heritable language phenotype Broader autism phenotype Communication impairment Index. décimale : PER Périodiques Résumé : Extensive empirical evidence indicates that the lesser variant of Autism Spectrum Disorders (ASD) involves a communication impairment that is similar to, but milder than, the deficit in clinical ASD. This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband communication difficulties. ASD probands with at least one BAP parent (identified using the Autism Spectrum Quotient) had greater structural and pragmatic language difficulties (assessed using the Children’s Communication Checklist-2) than ASD probands with no BAP parent. This finding provides support for the position that genetic liability for ASD is associated with increased communication difficulties across structural and pragmatic domains. En ligne : http://dx.doi.org/10.1007/s10803-013-1838-3 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2187 Brief Report: Further Evidence for a Link Between Inner Speech Limitations and Executive Function in High-Functioning Children with Autism Spectrum Disorders / Suzanna N. RUSSELL-SMITH in Journal of Autism and Developmental Disorders, 44-5 (May 2014)
![]()
PermalinkCommentary: Are we expecting too much from the extreme male brain theory of autism? A reflection on Kung et al. (2016) / Andrew J. O. WHITEHOUSE in Journal of Child Psychology and Psychiatry, 57-12 (December 2016)
![]()
PermalinkEvidence for Distinct Cognitive Profiles in Autism Spectrum Disorders and Specific Language Impairment / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 44-1 (January 2014)
![]()
PermalinkEvidence of a reduction over time in the behavioral severity of autistic disorder diagnoses / Andrew J. O. WHITEHOUSE in Autism Research, 10-1 (January 2017)
![]()
PermalinkInvestigating facial phenotype in autism spectrum conditions: The importance of a hypothesis driven approach / Maryam BOUTRUS in Autism Research, 10-12 (December 2017)
![]()
PermalinkMothers of Children with Autism have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child / Jennifer C. FAIRTHORNE in Journal of Autism and Developmental Disorders, 46-9 (September 2016)
![]()
PermalinkPrenatal maternal stress events and phenotypic outcomes in Autism Spectrum Disorder / Kandice J. VARCIN in Autism Research, 10-11 (November 2017)
![]()
PermalinkA Prospective Ultrasound Study of Prenatal Growth in Infant Siblings of Children With Autism / Lisa M. UNWIN in Autism Research, 9-2 (February 2016)
![]()
PermalinkA randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder / Andrew J. O. WHITEHOUSE in Journal of Child Psychology and Psychiatry, 58-9 (September 2017)
![]()
PermalinkA Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study / Rebecca ARMSTRONG in Journal of Autism and Developmental Disorders, 47-5 (May 2017)
![]()
Permalink
Centre d'Information et de Documentation
du CRA Rhône-Alpes
Se connecter
Mot de passe oublié ?Météo
Adresse
Centre d'Information et de Documentationdu CRA Rhône-Alpes
Centre Hospitalier le Vinatier, bât.211
95, Bd Pinel
F-69677 BRON
Horaires :
Lundi au Vendredi :
9h00 12h30 - 13h30 17h00
Tél:+33(0)4 37 91 54 65
Fax: +33(0)4 37 91 54 37
contact