Dépouillements

Meditation as a Potential Therapy for Autism: A Review / Sonia SEQUEIRA in Autism Research and Treatment, (April 2012)  

Public ISBD [article]  inAutism Research and Treatment > (April 2012) . - 11 p. Titre : Meditation as a Potential Therapy for Autism: A Review Type de document : Texte imprimé et/ou numérique Auteurs : Sonia SEQUEIRA, Auteur ; Ahmed MAHIUDDIN, Auteur Année de publication : 2012 Article en page(s) : 11 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism is a chronic neurodevelopmental disorder of unknown cause that affects approximately 1–3 percent of children and four times more boys than girls. Its prevalence is global and its social impact is devastating. In autism, the brain is unable to process sensory information normally. Instead, simple stimuli from the outside world are experienced as overwhelmingly intense and strain the emotional centers of the brain. A stress response to the incoming information is initiated that destabilizes cognitive networks and short-circuits adequate behavioral output. As a result, the child is unable to respond adequately to stimulation and initiate social behavior towards family, friends, and peers. In addition, these children typically face immune-digestive disorders that heighten social fears, anxieties, and internal conflicts. While it is critical to treat the physical symptoms, it is equally vital to offer an evidence-based holistic solution that harmonizes both their emotional and physical well-being as they move from childhood into adult life. Here, we summarize evidence from clinical studies and neuroscience research that suggests that an approach built on yogic principles and meditative tools is worth pursuing. Desired outcomes include relief of clinical symptoms of the disease, greater relaxation, and facilitated expression of feelings and skills, as well as improved family and social quality of life. En ligne : http://dx.doi.org/10.1155/2012/835847 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Meditation as a Potential Therapy for Autism: A Review [Texte imprimé et/ou numérique] / Sonia SEQUEIRA, Auteur ; Ahmed MAHIUDDIN, Auteur . - 2012 . - 11 p. Langues : Anglais (eng) in Autism Research and Treatment > (April 2012) . - 11 p. Index. décimale : PER Périodiques Résumé : Autism is a chronic neurodevelopmental disorder of unknown cause that affects approximately 1–3 percent of children and four times more boys than girls. Its prevalence is global and its social impact is devastating. In autism, the brain is unable to process sensory information normally. Instead, simple stimuli from the outside world are experienced as overwhelmingly intense and strain the emotional centers of the brain. A stress response to the incoming information is initiated that destabilizes cognitive networks and short-circuits adequate behavioral output. As a result, the child is unable to respond adequately to stimulation and initiate social behavior towards family, friends, and peers. In addition, these children typically face immune-digestive disorders that heighten social fears, anxieties, and internal conflicts. While it is critical to treat the physical symptoms, it is equally vital to offer an evidence-based holistic solution that harmonizes both their emotional and physical well-being as they move from childhood into adult life. Here, we summarize evidence from clinical studies and neuroscience research that suggests that an approach built on yogic principles and meditative tools is worth pursuing. Desired outcomes include relief of clinical symptoms of the disease, greater relaxation, and facilitated expression of feelings and skills, as well as improved family and social quality of life. En ligne : http://dx.doi.org/10.1155/2012/835847 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients / Giorgio PINI in Autism Research and Treatment, (April 2012)  

Public ISBD [article]  inAutism Research and Treatment > (April 2012) . - 14 p. Titre : IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients Type de document : Texte imprimé et/ou numérique Auteurs : Giorgio PINI, Auteur ; Maria Flora SCUSA, Auteur ; Laura CONGIU, Auteur ; Alberto BENINCASA, Auteur ; Paolina MORESCALCHI, Auteur ; Ilaria BOTTIGLIONI, Auteur ; Pietro DI MARCO, Auteur ; Paolo BORELLI, Auteur ; Ubaldo BONUCCELLI, Auteur ; Andrea DELLA-CHIESA, Auteur ; Adriele PRINA-MELLO, Auteur ; Daniela TROPEA, Auteur Année de publication : 2012 Article en page(s) : 14 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Rett syndrome (RTT) is a devastating neurodevelopmental disorder that affects one in ten thousand girls and has no cure. The majority of RTT patients display mutations in the gene that codes for the methyl-CpG-binding protein 2 (MeCP2). Clinical observations and neurobiological analysis of mouse models suggest that defects in the expression of MeCP2 protein compromise the development of the central nervous system, especially synaptic and circuit maturation. Thus, agents that promote brain development and synaptic function, such as insulin-like growth factor 1 (IGF1), are good candidates for ameliorating the symptoms of RTT. IGF1 and its active peptide, (1–3) IGF1, cross the blood brain barrier, and (1–3) IGF1 ameliorates the symptoms of RTT in a mouse model of the disease; therefore they are ideal treatments for neurodevelopmental disorders, including RTT. We performed a pilot study to establish whether there are major risks associated with IGF1 administration in RTT patients. Six young girls with classic RTT received IGF1 subcutaneous injections twice a day for six months, and they were regularly monitored by their primary care physicians and by the unit for RTT in Versilia Hospital (Italy). This study shows that there are no risks associated with IGF1 administration. En ligne : http://dx.doi.org/10.1155/2012/679801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients [Texte imprimé et/ou numérique] / Giorgio PINI, Auteur ; Maria Flora SCUSA, Auteur ; Laura CONGIU, Auteur ; Alberto BENINCASA, Auteur ; Paolina MORESCALCHI, Auteur ; Ilaria BOTTIGLIONI, Auteur ; Pietro DI MARCO, Auteur ; Paolo BORELLI, Auteur ; Ubaldo BONUCCELLI, Auteur ; Andrea DELLA-CHIESA, Auteur ; Adriele PRINA-MELLO, Auteur ; Daniela TROPEA, Auteur . - 2012 . - 14 p. Langues : Anglais (eng) in Autism Research and Treatment > (April 2012) . - 14 p. Index. décimale : PER Périodiques Résumé : Rett syndrome (RTT) is a devastating neurodevelopmental disorder that affects one in ten thousand girls and has no cure. The majority of RTT patients display mutations in the gene that codes for the methyl-CpG-binding protein 2 (MeCP2). Clinical observations and neurobiological analysis of mouse models suggest that defects in the expression of MeCP2 protein compromise the development of the central nervous system, especially synaptic and circuit maturation. Thus, agents that promote brain development and synaptic function, such as insulin-like growth factor 1 (IGF1), are good candidates for ameliorating the symptoms of RTT. IGF1 and its active peptide, (1–3) IGF1, cross the blood brain barrier, and (1–3) IGF1 ameliorates the symptoms of RTT in a mouse model of the disease; therefore they are ideal treatments for neurodevelopmental disorders, including RTT. We performed a pilot study to establish whether there are major risks associated with IGF1 administration in RTT patients. Six young girls with classic RTT received IGF1 subcutaneous injections twice a day for six months, and they were regularly monitored by their primary care physicians and by the unit for RTT in Versilia Hospital (Italy). This study shows that there are no risks associated with IGF1 administration. En ligne : http://dx.doi.org/10.1155/2012/679801 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

Improving Psychiatric Hospital Care for Pediatric Patients with Autism Spectrum Disorders and Intellectual Disabilities / Robin GABRIELS in Autism Research and Treatment, (April 2012)  

Public ISBD [article]  inAutism Research and Treatment > (April 2012) . - 7 p. Titre : Improving Psychiatric Hospital Care for Pediatric Patients with Autism Spectrum Disorders and Intellectual Disabilities Type de document : Texte imprimé et/ou numérique Auteurs : Robin GABRIELS, Auteur ; John A. AGNEW, Auteur ; Carol BERESFORD, Auteur ; Mary Ann MORROW, Auteur ; Gary MESIBOV, Auteur ; Marianne Z. WAMBOLDT, Auteur Année de publication : 2012 Article en page(s) : 7 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Pediatric patients with autism spectrum disorders (ASD) and/or intellectual disabilities (ID) are at greater risk for psychiatric hospitalization compared to children with other disorders. However, general psychiatric hospital environments are not adapted for the unique learning styles, needs, and abilities of this population, and there are few specialized hospital-based psychiatric care programs in the United States. This paper compares patient outcomes from a specialized psychiatric hospital program developed for pediatric patients with an ASD and/or ID to prior outcomes of this patient population in a general psychiatric program at a children’s hospital. Record review data indicate improved outcomes for patients in the specialized program of reduced recidivism rates (12% versus 33%) and decreased average lengths of inpatient stay (as short as 26 days versus 45 days). Available data from a subset of patients ( �� = 4 3 ) in the specialized program showed a decrease in irritability and hyperactivity behaviors from admission to discharge and that 35 previously undetected ASD diagnoses were made. Results from this preliminary study support specialized psychiatric care practices with this population to positively impact their health care outcomes. En ligne : http://dx.doi.org/10.1155/2012/685053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Improving Psychiatric Hospital Care for Pediatric Patients with Autism Spectrum Disorders and Intellectual Disabilities [Texte imprimé et/ou numérique] / Robin GABRIELS, Auteur ; John A. AGNEW, Auteur ; Carol BERESFORD, Auteur ; Mary Ann MORROW, Auteur ; Gary MESIBOV, Auteur ; Marianne Z. WAMBOLDT, Auteur . - 2012 . - 7 p. Langues : Anglais (eng) in Autism Research and Treatment > (April 2012) . - 7 p. Index. décimale : PER Périodiques Résumé : Pediatric patients with autism spectrum disorders (ASD) and/or intellectual disabilities (ID) are at greater risk for psychiatric hospitalization compared to children with other disorders. However, general psychiatric hospital environments are not adapted for the unique learning styles, needs, and abilities of this population, and there are few specialized hospital-based psychiatric care programs in the United States. This paper compares patient outcomes from a specialized psychiatric hospital program developed for pediatric patients with an ASD and/or ID to prior outcomes of this patient population in a general psychiatric program at a children’s hospital. Record review data indicate improved outcomes for patients in the specialized program of reduced recidivism rates (12% versus 33%) and decreased average lengths of inpatient stay (as short as 26 days versus 45 days). Available data from a subset of patients ( �� = 4 3 ) in the specialized program showed a decrease in irritability and hyperactivity behaviors from admission to discharge and that 35 previously undetected ASD diagnoses were made. Results from this preliminary study support specialized psychiatric care practices with this population to positively impact their health care outcomes. En ligne : http://dx.doi.org/10.1155/2012/685053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

Is Autism a Member of a Family of Diseases Resulting from Genetic/Cultural Mismatches? Implications for Treatment and Prevention / Staci D. BILBO in Autism Research and Treatment, (April 2012)  

Public ISBD [article]  inAutism Research and Treatment > (April 2012) . - 11 p. Titre : Is Autism a Member of a Family of Diseases Resulting from Genetic/Cultural Mismatches? Implications for Treatment and Prevention Type de document : Texte imprimé et/ou numérique Auteurs : Staci D. BILBO, Auteur ; John P. JONES, Auteur ; William PARKER, Auteur Année de publication : 2012 Article en page(s) : 11 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Several lines of evidence support the view that autism is a typical member of a large family of immune-related, noninfectious, chronic diseases associated with postindustrial society. This family of diseases includes a wide range of inflammatory, allergic, and autoimmune diseases and results from consequences of genetic/culture mismatches which profoundly destabilize the immune system. Principle among these consequences is depletion of important components, particularly helminths, from the ecosystem of the human body, the human biome. Autism shares a wide range of features in common with this family of diseases, including the contribution of genetics/epigenetics, the identification of disease-inducing triggers, the apparent role of immunity in pathogenesis, high prevalence, complex etiologies and manifestations, and potentially some aspects of epidemiology. Fortunately, using available resources and technology, modern medicine has the potential to effectively reconstitute the human biome, thus treating or even avoiding altogether the consequences of genetic/cultural mismatches which underpin this entire family of disease. Thus, if indeed autism is an epidemic of postindustrial society associated with immune hypersensitivity, we can expect that the disease is readily preventable. En ligne : http://dx.doi.org/10.1155/2012/910946 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Is Autism a Member of a Family of Diseases Resulting from Genetic/Cultural Mismatches? Implications for Treatment and Prevention [Texte imprimé et/ou numérique] / Staci D. BILBO, Auteur ; John P. JONES, Auteur ; William PARKER, Auteur . - 2012 . - 11 p. Langues : Anglais (eng) in Autism Research and Treatment > (April 2012) . - 11 p. Index. décimale : PER Périodiques Résumé : Several lines of evidence support the view that autism is a typical member of a large family of immune-related, noninfectious, chronic diseases associated with postindustrial society. This family of diseases includes a wide range of inflammatory, allergic, and autoimmune diseases and results from consequences of genetic/culture mismatches which profoundly destabilize the immune system. Principle among these consequences is depletion of important components, particularly helminths, from the ecosystem of the human body, the human biome. Autism shares a wide range of features in common with this family of diseases, including the contribution of genetics/epigenetics, the identification of disease-inducing triggers, the apparent role of immunity in pathogenesis, high prevalence, complex etiologies and manifestations, and potentially some aspects of epidemiology. Fortunately, using available resources and technology, modern medicine has the potential to effectively reconstitute the human biome, thus treating or even avoiding altogether the consequences of genetic/cultural mismatches which underpin this entire family of disease. Thus, if indeed autism is an epidemic of postindustrial society associated with immune hypersensitivity, we can expect that the disease is readily preventable. En ligne : http://dx.doi.org/10.1155/2012/910946 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178