Acute neuropsychological effects of methylphenidate in stimulant drug-naïve boys with ADHD II – broader executive and non-executive domains / Sinéad M. RHODES in Journal of Child Psychology and Psychiatry, 47-11 (November 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-11 (November 2006) . - p.1184–1194 Titre : Acute neuropsychological effects of methylphenidate in stimulant drug-naïve boys with ADHD II – broader executive and non-executive domains Type de document : Texte imprimé et/ou numérique Auteurs : Sinéad M. RHODES, Auteur ; David R. COGHILL, Auteur ; Keith MATTHEWS, Auteur Année de publication : 2007 Article en page(s) : p.1184–1194 Langues : Anglais (eng) Mots-clés : ADHD stimulant methylphenidate cognition executive-functioning self-regulation Index. décimale : PER Périodiques Résumé : Background: Accumulating evidence supports methylphenidate-induced enhancement of neuropsychological functioning in attention deficit hyperactivity disorder (ADHD). The present study was designed to investigate the acute effects of the psychostimulant drug, methylphenidate (MPH), on neuropsychological performance in stimulant naïve boys with ADHD. Methods: Seventy-three drug-naïve boys (age 7–15) with ADHD (combined type) completed neuropsychological tasks from the CANTAB battery under randomised, placebo controlled, double-blind conditions following an acute challenge with either placebo (n = 24), .3 (n = 25) or .6 (n = 24) mg/kg oral MPH. Results: MPH did not impair performance on any task. MPH (.6 mg/kg) lengthened response latencies on a task of Spatial Recognition, shortened response times on a Reaction Time task and restored performance on a Delayed Matching to Sample visual, non-working memory task. Contrary to predictions, MPH did not enhance performance on tasks with a prominent executive component, including Go/NoGo, Spatial Working Memory, Stockings of Cambridge and Attentional Set shifting tasks. Conclusions: Acute administration of MPH to drug-naïve boys with ADHD did not impair neuropsychological performance. Acute MPH enhanced performance on some aspects of non-executive functioning. MPH-induced slowing of responding on a relatively complex Spatial Recognition memory task and quickened responding on a reaction time task requiring less cognitive resources suggests that MPH may act by improving self-regulatory ability. MPH may not exert its effects on neuropsychological functioning by enhancing executive processes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01633.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=809 [article] Acute neuropsychological effects of methylphenidate in stimulant drug-naïve boys with ADHD II – broader executive and non-executive domains [Texte imprimé et/ou numérique] / Sinéad M. RHODES, Auteur ; David R. COGHILL, Auteur ; Keith MATTHEWS, Auteur . - 2007 . - p.1184–1194. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-11 (November 2006) . - p.1184–1194 Mots-clés : ADHD stimulant methylphenidate cognition executive-functioning self-regulation Index. décimale : PER Périodiques Résumé : Background: Accumulating evidence supports methylphenidate-induced enhancement of neuropsychological functioning in attention deficit hyperactivity disorder (ADHD). The present study was designed to investigate the acute effects of the psychostimulant drug, methylphenidate (MPH), on neuropsychological performance in stimulant naïve boys with ADHD. Methods: Seventy-three drug-naïve boys (age 7–15) with ADHD (combined type) completed neuropsychological tasks from the CANTAB battery under randomised, placebo controlled, double-blind conditions following an acute challenge with either placebo (n = 24), .3 (n = 25) or .6 (n = 24) mg/kg oral MPH. Results: MPH did not impair performance on any task. MPH (.6 mg/kg) lengthened response latencies on a task of Spatial Recognition, shortened response times on a Reaction Time task and restored performance on a Delayed Matching to Sample visual, non-working memory task. Contrary to predictions, MPH did not enhance performance on tasks with a prominent executive component, including Go/NoGo, Spatial Working Memory, Stockings of Cambridge and Attentional Set shifting tasks. Conclusions: Acute administration of MPH to drug-naïve boys with ADHD did not impair neuropsychological performance. Acute MPH enhanced performance on some aspects of non-executive functioning. MPH-induced slowing of responding on a relatively complex Spatial Recognition memory task and quickened responding on a reaction time task requiring less cognitive resources suggests that MPH may act by improving self-regulatory ability. MPH may not exert its effects on neuropsychological functioning by enhancing executive processes. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01633.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=809

Annual Research Review: Categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders – implications of recent empirical / David R. COGHILL in Journal of Child Psychology and Psychiatry, 53-5 (May 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-5 (May 2012) . - p.469-489 Titre : Annual Research Review: Categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders – implications of recent empirical Type de document : Texte imprimé et/ou numérique Auteurs : David R. COGHILL, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur Année de publication : 2012 Article en page(s) : p.469-489 Langues : Anglais (eng) Mots-clés : Assessment  classification  diagnosis  DSM  factor analysis  ICD  taxometrics Index. décimale : PER Périodiques Résumé : The question of whether child and adolescent mental disorders are best classified using dimensional or categorical approaches is a contentious one that has equally profound implications for clinical practice and scientific enquiry. Here, we explore this issue in the context of the forth coming publication of the DSM-5 and ICD-11 approaches to classification and diagnosis and in the light of recent empirical studies. First, we provide an overview of current category-based systems and dimensional alternatives. Second, we distinguish the various strands of meaning and levels of analysis implied when we talk about categories and dimensions of mental disorder – distinguishing practical clinical necessity, formal diagnostic systems, meta-theoretical beliefs and empirical reality. Third, we introduce the different statistical techniques developed to identify disorder dimensions and categories in childhood populations and to test between categorical and dimensional models. Fourth, we summarise the empirical evidence from recent taxometric studies in favour of the ‘taxonomic hypothesis’ that mental disorder categories reflect discrete entities with putative specific causes. Finally, we explore the implications of these findings for clinical practice and science. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02511.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154 [article] Annual Research Review: Categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders – implications of recent empirical [Texte imprimé et/ou numérique] / David R. COGHILL, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur . - 2012 . - p.469-489. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-5 (May 2012) . - p.469-489 Mots-clés : Assessment  classification  diagnosis  DSM  factor analysis  ICD  taxometrics Index. décimale : PER Périodiques Résumé : The question of whether child and adolescent mental disorders are best classified using dimensional or categorical approaches is a contentious one that has equally profound implications for clinical practice and scientific enquiry. Here, we explore this issue in the context of the forth coming publication of the DSM-5 and ICD-11 approaches to classification and diagnosis and in the light of recent empirical studies. First, we provide an overview of current category-based systems and dimensional alternatives. Second, we distinguish the various strands of meaning and levels of analysis implied when we talk about categories and dimensions of mental disorder – distinguishing practical clinical necessity, formal diagnostic systems, meta-theoretical beliefs and empirical reality. Third, we introduce the different statistical techniques developed to identify disorder dimensions and categories in childhood populations and to test between categorical and dimensional models. Fourth, we summarise the empirical evidence from recent taxometric studies in favour of the ‘taxonomic hypothesis’ that mental disorder categories reflect discrete entities with putative specific causes. Finally, we explore the implications of these findings for clinical practice and science. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02511.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=154

Commentary response: Addressing the challenges – response to the commentary of Jarrold and Hall (2012) / David R. COGHILL in Journal of Child Psychology and Psychiatry, 53-2 (February 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.141-142 Titre : Commentary response: Addressing the challenges – response to the commentary of Jarrold and Hall (2012) Type de document : Texte imprimé et/ou numérique Auteurs : David R. COGHILL, Auteur ; Sinéad M. RHODES, Auteur Année de publication : 2012 Article en page(s) : p.141-142 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02506.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150 [article] Commentary response: Addressing the challenges – response to the commentary of Jarrold and Hall (2012) [Texte imprimé et/ou numérique] / David R. COGHILL, Auteur ; Sinéad M. RHODES, Auteur . - 2012 . - p.141-142. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.141-142 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02506.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150

A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder / Sinéad M. RHODES in Journal of Child Psychology and Psychiatry, 53-2 (February 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.128-137 Titre : A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sinéad M. RHODES, Auteur ; Joanne PARK, Auteur ; Sarah SETH, Auteur ; David R. COGHILL, Auteur Année de publication : 2012 Article en page(s) : p.128-137 Langues : Anglais (eng) Mots-clés : Working memory  long-term memory  executive function  ADHD  ODD Index. décimale : PER Périodiques Résumé : Background:  We conducted a comprehensive and systematic assessment of memory functioning in drug-naïve boys with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Methods:  Boys performed verbal and spatial working memory (WM) component (storage and central executive) and verbal and spatial storage load tasks, and the spatial span, spatial executive WM, spatial recognition memory and verbal recognition memory tasks from the Cambridge Neuropsychological Test Automated Battery. Groups comprised: (a) ADHD only (N = 21); (b) ADHD+ODD (N = 27); (c) ODD only (N = 21); and (d) typically developing (TYP) boys (N = 26). Groups were matched for age (M = 9.7 years) and sex (all boys). Results:  Confirmatory factor analyses confirmed the presence of five factors: verbal functioning, spatial functioning, WM storage, WM central executive and long-term memory (LTM). All three clinical groups demonstrated impaired memory performance. Boys with ODD and ODD+ADHD but not ADHD alone performed poorly on verbal memory tasks, whilst all three clinical groups showed impaired performance on spatial memory tasks. All three clinical groups performed poorly on the storage and central executive WM factors and the LTM factor. Conclusions:  ADHD and ODD are characterised by impaired performance storage and central executive WM tasks and LTM tasks. This is, we believe, the first report of impaired WM and LTM performance in ODD. This study suggests that verbal memory difficulties are more closely associated with ODD than ADHD symptoms and that combined ADHD+ODD represents a true comorbidity. The data also support a small but growing number of suggestions in the literature of impaired LTM in ADHD. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02436.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150 [article] A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder [Texte imprimé et/ou numérique] / Sinéad M. RHODES, Auteur ; Joanne PARK, Auteur ; Sarah SETH, Auteur ; David R. COGHILL, Auteur . - 2012 . - p.128-137. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.128-137 Mots-clés : Working memory  long-term memory  executive function  ADHD  ODD Index. décimale : PER Périodiques Résumé : Background:  We conducted a comprehensive and systematic assessment of memory functioning in drug-naïve boys with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Methods:  Boys performed verbal and spatial working memory (WM) component (storage and central executive) and verbal and spatial storage load tasks, and the spatial span, spatial executive WM, spatial recognition memory and verbal recognition memory tasks from the Cambridge Neuropsychological Test Automated Battery. Groups comprised: (a) ADHD only (N = 21); (b) ADHD+ODD (N = 27); (c) ODD only (N = 21); and (d) typically developing (TYP) boys (N = 26). Groups were matched for age (M = 9.7 years) and sex (all boys). Results:  Confirmatory factor analyses confirmed the presence of five factors: verbal functioning, spatial functioning, WM storage, WM central executive and long-term memory (LTM). All three clinical groups demonstrated impaired memory performance. Boys with ODD and ODD+ADHD but not ADHD alone performed poorly on verbal memory tasks, whilst all three clinical groups showed impaired performance on spatial memory tasks. All three clinical groups performed poorly on the storage and central executive WM factors and the LTM factor. Conclusions:  ADHD and ODD are characterised by impaired performance storage and central executive WM tasks and LTM tasks. This is, we believe, the first report of impaired WM and LTM performance in ODD. This study suggests that verbal memory difficulties are more closely associated with ODD than ADHD symptoms and that combined ADHD+ODD represents a true comorbidity. The data also support a small but growing number of suggestions in the literature of impaired LTM in ADHD. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02436.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150

Editorial: Do clinical services need to take conduct disorder more seriously? / David R. COGHILL in Journal of Child Psychology and Psychiatry, 54-9 (September 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-9 (September 2013) . - p.921-923 Titre : Editorial: Do clinical services need to take conduct disorder more seriously? Type de document : Texte imprimé et/ou numérique Auteurs : David R. COGHILL, Auteur Article en page(s) : p.921-923 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Oppositional defiant disorder (ODD) and conduct disorder are common disorders and frequent reasons for referral to child and adolescent mental health services (CAMHS). Figures from epidemiological studies in the US suggest that around 10% of children suffer from ODD and similar numbers from CD. Data from the UK estimates that around 6% of children and young people aged 5 to 16 years have a clinically diagnosed conduct disorder in England, with much higher rates in males than females. En ligne : http://dx.doi.org/10.1111/jcpp.12135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Editorial: Do clinical services need to take conduct disorder more seriously? [Texte imprimé et/ou numérique] / David R. COGHILL, Auteur . - p.921-923. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-9 (September 2013) . - p.921-923 Index. décimale : PER Périodiques Résumé : Oppositional defiant disorder (ODD) and conduct disorder are common disorders and frequent reasons for referral to child and adolescent mental health services (CAMHS). Figures from epidemiological studies in the US suggest that around 10% of children suffer from ODD and similar numbers from CD. Data from the UK estimates that around 6% of children and young people aged 5 to 16 years have a clinically diagnosed conduct disorder in England, with much higher rates in males than females. En ligne : http://dx.doi.org/10.1111/jcpp.12135 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Editorial: Focusing on a moving target: key themes for research and practice in adolescent mental health / Barbara MAUGHAN in Journal of Child Psychology and Psychiatry, 52-10 (October 2011)  

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Editorial: Getting the basics right in mental health assessments of children and young people / David R. COGHILL in Journal of Child Psychology and Psychiatry, 53-8 (August 2012)  

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Editorial: taking our time – a long-term perspective on child and adolescent mental health provides invaluable insights for scientists, clinicians and policy makers / David R. COGHILL in Journal of Child Psychology and Psychiatry, 51-8 (August 2010)  

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Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents / Samuele CORTESE in Journal of Child Psychology and Psychiatry, 54-3 (March 2013)  

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Practitioner Review: Quality of life in child mental health – conceptual challenges and practical choices / David R. COGHILL in Journal of Child Psychology and Psychiatry, 50-5 (May 2009)  

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