Hypocortisolism as a potential marker of allostatic load in children: Associations with family risk and internalizing disorders / Lisa S. BADANES in Development and Psychopathology, 23-3 (August 2011)  

Public ISBD [article]  inDevelopment and Psychopathology > 23-3 (August 2011) . - p.881-896 Titre : Hypocortisolism as a potential marker of allostatic load in children: Associations with family risk and internalizing disorders Type de document : Texte imprimé et/ou numérique Auteurs : Lisa S. BADANES, Auteur ; Sarah E. WATAMURA, Auteur ; Benjamin L. HANKIN, Auteur Année de publication : 2011 Article en page(s) : p.881-896 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Although the majority of research attention to the hypothalamic–pituitary–adrenal (HPA) axis in stress-related disorders and as a marker of allostatic load has focused on overactivation of this stress system, theory and data clearly indicate that underactivation is also an important type of dysregulation. In the current study we focused on low cortisol, exploring a constellation of risk factors including stress exposure, maternal depression, and attenuated basal and stress reactive cortisol in two samples of children. The first sample was comprised of 110 preschoolers living in high-stress environments. Cortisol was assessed across the day at home and at child care as well as across two stress paradigms. These data were used to classify whether children's HPA axis activity was attenuated. Serious family financial strain, maternal depression, and attenuated cortisol all made unique contributions in models predicting current clinical levels of internalizing symptoms as rated by mothers and teachers. The second sample was 166 third, sixth, and ninth graders studied five times across a 1-year period. Maternal and child depression were determined through structured clinical interviews, and stress exposure was assessed via checklist and interview techniques with the child and parent. Cortisol was assessed multiple times across a lab visit at Time 1, and these data were combined into a single continuous measure. Cortisol concentrations across the lab visit interacted with stress exposure across the year such that children with lower average cortisol at Time 1 and increased stress across the 12 months showed elevated levels of internalizing symptoms. Based on these and related data we propose that prior to puberty low cortisol may be an important marker of allostatic load, particularly for risk of depression and anxiety. En ligne : http://dx.doi.org/10.1017/S095457941100037X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132 [article] Hypocortisolism as a potential marker of allostatic load in children: Associations with family risk and internalizing disorders [Texte imprimé et/ou numérique] / Lisa S. BADANES, Auteur ; Sarah E. WATAMURA, Auteur ; Benjamin L. HANKIN, Auteur . - 2011 . - p.881-896. Langues : Anglais (eng) in Development and Psychopathology > 23-3 (August 2011) . - p.881-896 Index. décimale : PER Périodiques Résumé : Although the majority of research attention to the hypothalamic–pituitary–adrenal (HPA) axis in stress-related disorders and as a marker of allostatic load has focused on overactivation of this stress system, theory and data clearly indicate that underactivation is also an important type of dysregulation. In the current study we focused on low cortisol, exploring a constellation of risk factors including stress exposure, maternal depression, and attenuated basal and stress reactive cortisol in two samples of children. The first sample was comprised of 110 preschoolers living in high-stress environments. Cortisol was assessed across the day at home and at child care as well as across two stress paradigms. These data were used to classify whether children's HPA axis activity was attenuated. Serious family financial strain, maternal depression, and attenuated cortisol all made unique contributions in models predicting current clinical levels of internalizing symptoms as rated by mothers and teachers. The second sample was 166 third, sixth, and ninth graders studied five times across a 1-year period. Maternal and child depression were determined through structured clinical interviews, and stress exposure was assessed via checklist and interview techniques with the child and parent. Cortisol was assessed multiple times across a lab visit at Time 1, and these data were combined into a single continuous measure. Cortisol concentrations across the lab visit interacted with stress exposure across the year such that children with lower average cortisol at Time 1 and increased stress across the 12 months showed elevated levels of internalizing symptoms. Based on these and related data we propose that prior to puberty low cortisol may be an important marker of allostatic load, particularly for risk of depression and anxiety. En ligne : http://dx.doi.org/10.1017/S095457941100037X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132

Parental depression and child cognitive vulnerability predict children's cortisol reactivity / Elizabeth P. HAYDEN in Development and Psychopathology, 26-4 (Part 2) (November 2014)  

Public ISBD [article]  inDevelopment and Psychopathology > 26-4 (Part 2) (November 2014) . - p.1445-1460 Titre : Parental depression and child cognitive vulnerability predict children's cortisol reactivity Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth P. HAYDEN, Auteur ; Benjamin L. HANKIN, Auteur ; Sarah V. M. MACKRELL, Auteur ; Haroon I. SHEIKH, Auteur ; Patricia L. JORDAN, Auteur ; David J. A. DOZOIS, Auteur ; Shiva M. SINGH, Auteur ; Thomas M. OLINO, Auteur ; Lisa S. BADANES, Auteur Article en page(s) : p.1445-1460 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Risk for depression is expressed across multiple levels of analysis. For example, parental depression and cognitive vulnerability are known markers of depression risk, but no study has examined their interactive effects on children's cortisol reactivity, a likely mediator of early depression risk. We examined relations across these different levels of vulnerability using cross-sectional and longitudinal methods in two community samples of children. Children were assessed for cognitive vulnerability using self-reports (Study 1; n = 244) and tasks tapping memory and attentional bias (Study 2; n = 205), and their parents were assessed for depression history using structured clinical interviews. In both samples, children participated in standardized stress tasks and cortisol reactivity was assessed. Cross-sectionally and longitudinally, parental depression history and child cognitive vulnerability interacted to predict children's cortisol reactivity; associations between parent depression and elevated child cortisol activity were found when children also showed elevated depressotypic attributions as well as attentional and memory biases. Findings indicate that models of children's emerging depression risk may benefit from the examination of the interactive effects of multiple sources of vulnerability across levels of analysis. En ligne : http://dx.doi.org/10.1017/S0954579414001138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245 [article] Parental depression and child cognitive vulnerability predict children's cortisol reactivity [Texte imprimé et/ou numérique] / Elizabeth P. HAYDEN, Auteur ; Benjamin L. HANKIN, Auteur ; Sarah V. M. MACKRELL, Auteur ; Haroon I. SHEIKH, Auteur ; Patricia L. JORDAN, Auteur ; David J. A. DOZOIS, Auteur ; Shiva M. SINGH, Auteur ; Thomas M. OLINO, Auteur ; Lisa S. BADANES, Auteur . - p.1445-1460. Langues : Anglais (eng) in Development and Psychopathology > 26-4 (Part 2) (November 2014) . - p.1445-1460 Index. décimale : PER Périodiques Résumé : Risk for depression is expressed across multiple levels of analysis. For example, parental depression and cognitive vulnerability are known markers of depression risk, but no study has examined their interactive effects on children's cortisol reactivity, a likely mediator of early depression risk. We examined relations across these different levels of vulnerability using cross-sectional and longitudinal methods in two community samples of children. Children were assessed for cognitive vulnerability using self-reports (Study 1; n = 244) and tasks tapping memory and attentional bias (Study 2; n = 205), and their parents were assessed for depression history using structured clinical interviews. In both samples, children participated in standardized stress tasks and cortisol reactivity was assessed. Cross-sectionally and longitudinally, parental depression history and child cognitive vulnerability interacted to predict children's cortisol reactivity; associations between parent depression and elevated child cortisol activity were found when children also showed elevated depressotypic attributions as well as attentional and memory biases. Findings indicate that models of children's emerging depression risk may benefit from the examination of the interactive effects of multiple sources of vulnerability across levels of analysis. En ligne : http://dx.doi.org/10.1017/S0954579414001138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245

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