[article]
| Titre : |
The contribution of gene–environment interaction to psychopathology |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Anita THAPAR, Auteur ; Frances RICE, Auteur ; Kate LANGLEY, Auteur ; Michael C. O'DONOVAN, Auteur ; Gordon T. HAROLD, Auteur |
| Année de publication : |
2007 |
| Article en page(s) : |
p.989-1004 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The study of gene–environment interaction (G × E) constitutes an area of significant social and clinical significance. Different types of research study designs are being used to investigate the contribution of G × E to psychopathology, although the term G × E has also been used and interpreted in different ways. Despite mixed evidence that G × E contributes to psychopathology, some promising and consistent findings are emerging. Evidence is reviewed in relation to depression, antisocial behavior, schizophrenia, and attention-deficit/hyperactivity disorder. Although findings from various research designs have different meaning, interestingly much of the evidence with regard to the contribution of G × E that has arisen from twin and adoption studies has been for antisocial behavior and depression. It is for these same forms of psychopathology that molecular genetic evidence of G × E has also been most convincing. Finally, current and anticipated methodological challenges and implications for future research in this area are considered. |
| En ligne : |
http://dx.doi.org/10.1017/s0954579407000491 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181 |
in Development and Psychopathology > 19-4 (Fall 2007) . - p.989-1004
[article] The contribution of gene–environment interaction to psychopathology [Texte imprimé et/ou numérique] / Anita THAPAR, Auteur ; Frances RICE, Auteur ; Kate LANGLEY, Auteur ; Michael C. O'DONOVAN, Auteur ; Gordon T. HAROLD, Auteur . - 2007 . - p.989-1004. Langues : Anglais ( eng) in Development and Psychopathology > 19-4 (Fall 2007) . - p.989-1004
| Index. décimale : |
PER Périodiques |
| Résumé : |
The study of gene–environment interaction (G × E) constitutes an area of significant social and clinical significance. Different types of research study designs are being used to investigate the contribution of G × E to psychopathology, although the term G × E has also been used and interpreted in different ways. Despite mixed evidence that G × E contributes to psychopathology, some promising and consistent findings are emerging. Evidence is reviewed in relation to depression, antisocial behavior, schizophrenia, and attention-deficit/hyperactivity disorder. Although findings from various research designs have different meaning, interestingly much of the evidence with regard to the contribution of G × E that has arisen from twin and adoption studies has been for antisocial behavior and depression. It is for these same forms of psychopathology that molecular genetic evidence of G × E has also been most convincing. Finally, current and anticipated methodological challenges and implications for future research in this area are considered. |
| En ligne : |
http://dx.doi.org/10.1017/s0954579407000491 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181 |
|
The contribution of gene–environment interaction to psychopathology in Development and Psychopathology, 19-4 (Fall 2007)
