[article]
Titre : |
Two-year diagnostic stability in early-onset first-episode psychosis |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Josefina CASTRO-FORNIELES, Auteur ; Elena DE LA SERNA, Auteur ; Ana GONZALEZ-PINTO, Auteur ; Mara PARELLADA, Auteur ; Montserrat GRAELL, Auteur ; Dolores MORENO, Auteur ; Soraya OTERO, Auteur ; Celso ARANGO, Auteur |
Année de publication : |
2011 |
Article en page(s) : |
p.1089-1098 |
Langues : |
Anglais (eng) |
Mots-clés : |
psychosis diagnosis schizophrenia bipolar disorder |
Index. décimale : |
PER Périodiques |
Résumé : |
Background: Only one study has used a prospective method to analyze the diagnostic stability of first psychotic episodes in children and adolescents. The Child and Adolescent First-Episode Psychosis Study (CAFEPS) is a 2-year, prospective longitudinal study of early-onset first episodes of psychosis (EO-FEP).
Aim: To describe diagnostic stability and the variables related to diagnostic changes.
Methods: Participants were 83 patients (aged 9–17 years) with an EO-FEP consecutively attended. They were assessed with a structured interview (Kiddie-Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version) and clinical scales at baseline and after 2 years.
Results: The global consistency for all diagnoses was 63.9%. The small group of bipolar disorder had high stability (92.31%) as did the group with schizophrenia spectrum disorders (90.00%). Depressive disorder had lower stability (37.50%) and the lowest values were for psychotic disorder not otherwise specified (11.76%) and brief psychotic disorder (0%).The most frequent diagnostic shift was to schizophrenia spectrum and bipolar disorders. One group of patients did not meet the criteria for any diagnosis at follow-up. Independent predictors of change to schizophrenia spectrum disorders were lower scores on the Children’s Global Assessment Scale (CGAS) and the Hamilton Depression Rating Scale. Predictors of not having a diagnosis at follow-up were the CGAS and the Strauss–Carpenter Outcome Scale.
Conclusions: Global diagnostic stability was 63.9%. Bipolar and schizophrenia spectrum disorders were the most stable diagnoses, while depressive disorder and other psychosis the least stable. Psychosocial functioning at baseline was a good predictor of diagnosis at follow-up. These data show the need for longitudinal follow-up in EO-FEP before a stable diagnosis is reached. |
En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2011.02443.x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142 |
in Journal of Child Psychology and Psychiatry > 52-10 (October 2011) . - p.1089-1098
[article] Two-year diagnostic stability in early-onset first-episode psychosis [Texte imprimé et/ou numérique] / Josefina CASTRO-FORNIELES, Auteur ; Elena DE LA SERNA, Auteur ; Ana GONZALEZ-PINTO, Auteur ; Mara PARELLADA, Auteur ; Montserrat GRAELL, Auteur ; Dolores MORENO, Auteur ; Soraya OTERO, Auteur ; Celso ARANGO, Auteur . - 2011 . - p.1089-1098. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 52-10 (October 2011) . - p.1089-1098
Mots-clés : |
psychosis diagnosis schizophrenia bipolar disorder |
Index. décimale : |
PER Périodiques |
Résumé : |
Background: Only one study has used a prospective method to analyze the diagnostic stability of first psychotic episodes in children and adolescents. The Child and Adolescent First-Episode Psychosis Study (CAFEPS) is a 2-year, prospective longitudinal study of early-onset first episodes of psychosis (EO-FEP).
Aim: To describe diagnostic stability and the variables related to diagnostic changes.
Methods: Participants were 83 patients (aged 9–17 years) with an EO-FEP consecutively attended. They were assessed with a structured interview (Kiddie-Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version) and clinical scales at baseline and after 2 years.
Results: The global consistency for all diagnoses was 63.9%. The small group of bipolar disorder had high stability (92.31%) as did the group with schizophrenia spectrum disorders (90.00%). Depressive disorder had lower stability (37.50%) and the lowest values were for psychotic disorder not otherwise specified (11.76%) and brief psychotic disorder (0%).The most frequent diagnostic shift was to schizophrenia spectrum and bipolar disorders. One group of patients did not meet the criteria for any diagnosis at follow-up. Independent predictors of change to schizophrenia spectrum disorders were lower scores on the Children’s Global Assessment Scale (CGAS) and the Hamilton Depression Rating Scale. Predictors of not having a diagnosis at follow-up were the CGAS and the Strauss–Carpenter Outcome Scale.
Conclusions: Global diagnostic stability was 63.9%. Bipolar and schizophrenia spectrum disorders were the most stable diagnoses, while depressive disorder and other psychosis the least stable. Psychosocial functioning at baseline was a good predictor of diagnosis at follow-up. These data show the need for longitudinal follow-up in EO-FEP before a stable diagnosis is reached. |
En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2011.02443.x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142 |
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