[article] 
inDevelopment and Psychopathology > 25-1 (February 2013) . - p.163-173

Titre :	Child dopamine active transporter 1 genotype and parenting: Evidence for evocative gene–environment correlations
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Elizabeth P. HAYDEN, Auteur ; Brigitte HANNA, Auteur ; Haroon I. SHEIKH, Auteur ; Rebecca S. LAPTOOK, Auteur ; Jiyon KIM, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur
Article en page(s) :	p.163-173
Index. décimale :	PER Périodiques
Résumé :	The dopamine active transporter 1 (DAT1) gene is implicated in psychopathology risk. Although the processes by which this gene exerts its effects on risk are poorly understood, a small body of research suggests that the DAT1 gene influences early emerging negative emotionality, a marker of children's psychopathology risk. As child negative emotionality evokes negative parenting practices, the DAT1 gene may also play a role in gene–environment correlations. To test this model, children (N = 365) were genotyped for the DAT1 gene and participated in standardized parent–child interaction tasks with their primary caregiver. The DAT1 gene 9-repeat variant was associated with child negative affect expressed toward the parent during parent–child interactions, and parents of children with a 9-repeat allele exhibited more hostility and lower guidance/engagement than parents of children without a 9-repeat allele. These gene–environment associations were partially mediated by child negative affect toward the parent. The findings implicate a specific polymorphism in eliciting negative parenting, suggesting that evocative associations play a role in elevating children's risk for emotional trajectories toward psychopathology risk.
En ligne :	http://dx.doi.org/10.1017/S0954579412000971
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190

[article] Child dopamine active transporter 1 genotype and parenting: Evidence for evocative gene–environment correlations [Texte imprimé et/ou numérique] / Elizabeth P. HAYDEN, Auteur ; Brigitte HANNA, Auteur ; Haroon I. SHEIKH, Auteur ; Rebecca S. LAPTOOK, Auteur ; Jiyon KIM, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur . - p.163-173.
in Development and Psychopathology > 25-1 (February 2013) . - p.163-173

Index. décimale :	PER Périodiques
Résumé :	The dopamine active transporter 1 (DAT1) gene is implicated in psychopathology risk. Although the processes by which this gene exerts its effects on risk are poorly understood, a small body of research suggests that the DAT1 gene influences early emerging negative emotionality, a marker of children's psychopathology risk. As child negative emotionality evokes negative parenting practices, the DAT1 gene may also play a role in gene–environment correlations. To test this model, children (N = 365) were genotyped for the DAT1 gene and participated in standardized parent–child interaction tasks with their primary caregiver. The DAT1 gene 9-repeat variant was associated with child negative affect expressed toward the parent during parent–child interactions, and parents of children with a 9-repeat allele exhibited more hostility and lower guidance/engagement than parents of children without a 9-repeat allele. These gene–environment associations were partially mediated by child negative affect toward the parent. The findings implicate a specific polymorphism in eliciting negative parenting, suggesting that evocative associations play a role in elevating children's risk for emotional trajectories toward psychopathology risk.
En ligne :	http://dx.doi.org/10.1017/S0954579412000971
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190