Children with very early onset obsessive-compulsive disorder: clinical features and treatment outcome / Eriko NAKATANI in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1261-1268 Titre : Children with very early onset obsessive-compulsive disorder: clinical features and treatment outcome Type de document : Texte imprimé et/ou numérique Auteurs : Eriko NAKATANI, Auteur ; Georgina KREBS, Auteur ; Nadia MICALI, Auteur ; Cynthia TURNER, Auteur ; Isobel HEYMAN, Auteur ; David MATAIX-COLS, Auteur Année de publication : 2011 Article en page(s) : p.1261-1268 Note générale : Obsessive-compulsive disorder; paediatric; age at onset; early onset; cognitive behaviour therapy Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background:  There is emerging evidence that early onset obsessive-compulsive disorder (OCD) may be a phenomenologically distinct subtype of the disorder. Previous research has shown that individuals who report an early onset display greater severity and persistence of symptoms, and they may be less responsive to treatment. To date, this question has been investigated solely in adult samples. The present study represents the first investigation into the effect of age at onset of OCD on clinical characteristics and response to treatment in a paediatric sample. Method:  A total of 365 young people referred to a specialist OCD clinic were included in the study. Clinical records were used to examine potential differences in key clinical characteristics between those who had a very early onset of the disorder (before 10 years) and those who had a late onset (10 years or later). Group differences in treatment responsiveness were also examined within a subgroup that received cognitive behaviour therapy (CBT) alone or CBT plus medication (n = 109). Results:  The very early onset group were characterised by a longer duration of illness, higher rates of comorbid tics, more frequent ordering and repeating compulsions and greater parent-reported psychosocial difficulties. There were no differences in treatment response between the groups, and when age at onset was examined as a continuous variable, it did not correlate with treatment response. Conclusions:  Very early onset OCD may be associated with different symptoms and comorbidities compared with late onset OCD. However, these differences do not appear to impact on responsiveness to developmentally tailored CBT alone or in combination with medication. These findings further indicate the value in early detection and treatment of OCD in childhood. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02434.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146 [article] Children with very early onset obsessive-compulsive disorder: clinical features and treatment outcome [Texte imprimé et/ou numérique] / Eriko NAKATANI, Auteur ; Georgina KREBS, Auteur ; Nadia MICALI, Auteur ; Cynthia TURNER, Auteur ; Isobel HEYMAN, Auteur ; David MATAIX-COLS, Auteur . - 2011 . - p.1261-1268. Obsessive-compulsive disorder; paediatric; age at onset; early onset; cognitive behaviour therapy Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1261-1268 Index. décimale : PER Périodiques Résumé : Background:  There is emerging evidence that early onset obsessive-compulsive disorder (OCD) may be a phenomenologically distinct subtype of the disorder. Previous research has shown that individuals who report an early onset display greater severity and persistence of symptoms, and they may be less responsive to treatment. To date, this question has been investigated solely in adult samples. The present study represents the first investigation into the effect of age at onset of OCD on clinical characteristics and response to treatment in a paediatric sample. Method:  A total of 365 young people referred to a specialist OCD clinic were included in the study. Clinical records were used to examine potential differences in key clinical characteristics between those who had a very early onset of the disorder (before 10 years) and those who had a late onset (10 years or later). Group differences in treatment responsiveness were also examined within a subgroup that received cognitive behaviour therapy (CBT) alone or CBT plus medication (n = 109). Results:  The very early onset group were characterised by a longer duration of illness, higher rates of comorbid tics, more frequent ordering and repeating compulsions and greater parent-reported psychosocial difficulties. There were no differences in treatment response between the groups, and when age at onset was examined as a continuous variable, it did not correlate with treatment response. Conclusions:  Very early onset OCD may be associated with different symptoms and comorbidities compared with late onset OCD. However, these differences do not appear to impact on responsiveness to developmentally tailored CBT alone or in combination with medication. These findings further indicate the value in early detection and treatment of OCD in childhood. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02434.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146

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