[article]
Titre : |
Commentary: Gene by environment interplay and psychopathology – in search of a paradigm |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Joel T. NIGG, Auteur |
Article en page(s) : |
p.1150-1152 |
Langues : |
Anglais (eng) |
Index. décimale : |
PER Périodiques |
Résumé : |
The articles in this Special Issue (SI) extend research on G×E in multiple ways, showing the growing importance of specifying kinds of G×E models (e.g., bioecological, susceptibility, stress-diathesis), incorporation of sophisticated ways of measuring types of G×E correlations (rGE), checking effects of statistical artifact, exemplifying an impressive range of quantitative and biological methodologies, and pointing to clearly needed next-step studies such as summarizing across many genes in gene sets (Bentley et al.) or in genome-wide pathway based approaches to G×E (Winham Biernacka) and prediction of clinical outcomes (Rapee et al.). As a group, they document nicely that gene × environment research has come of age. What is the import of this? Does it represent a major new development in our field, or merely an incremental change of a framework that remains fundamentally unchanged? |
En ligne : |
http://dx.doi.org/10.1111/jcpp.12134 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 |
in Journal of Child Psychology and Psychiatry > 54-10 (October 2013) . - p.1150-1152
[article] Commentary: Gene by environment interplay and psychopathology – in search of a paradigm [Texte imprimé et/ou numérique] / Joel T. NIGG, Auteur . - p.1150-1152. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 54-10 (October 2013) . - p.1150-1152
Index. décimale : |
PER Périodiques |
Résumé : |
The articles in this Special Issue (SI) extend research on G×E in multiple ways, showing the growing importance of specifying kinds of G×E models (e.g., bioecological, susceptibility, stress-diathesis), incorporation of sophisticated ways of measuring types of G×E correlations (rGE), checking effects of statistical artifact, exemplifying an impressive range of quantitative and biological methodologies, and pointing to clearly needed next-step studies such as summarizing across many genes in gene sets (Bentley et al.) or in genome-wide pathway based approaches to G×E (Winham Biernacka) and prediction of clinical outcomes (Rapee et al.). As a group, they document nicely that gene × environment research has come of age. What is the import of this? Does it represent a major new development in our field, or merely an incremental change of a framework that remains fundamentally unchanged? |
En ligne : |
http://dx.doi.org/10.1111/jcpp.12134 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 |
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