[article]
Titre : |
Effect of a ketogenic diet on autism spectrum disorder: A systematic review |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Kamila CASTRO, Auteur ; Larissa Slongo FACCIOLI, Auteur ; Diego BARONIO, Auteur ; Carmem GOTTFRIED, Auteur ; Ingrid Schweigert PERRY, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur |
Article en page(s) : |
p.31-38 |
Langues : |
Anglais (eng) |
Mots-clés : |
Autistic disorder Ketogenic diet Behavioural symptoms |
Index. décimale : |
PER Périodiques |
Résumé : |
Autism spectrum disorder (ASD) is primarily characterized by impaired social interaction and communication, as well as restricted repetitive behaviours and interests. The utilization of the ketogenic diet (KD) in different neurological disorders has become a valid approach over time, and recently, it has also been advocated as a potential therapeutic for ASD. A MEDLINE, Scopus and Cochrane search was performed by two independent reviewers to investigate the relationship between ASD and the KD in humans and experimental studies. Of the eighty-one potentially relevant articles, eight articles met the inclusion criteria: three studies with animals and five studies with humans. The consistency between reviewers was ? = 0.817. In humans, the studies mainly focused on the behavioural outcomes provided by this diet and reported ameliorated behavioural symptoms via an improved score in the Childhood Autism Rating Scale (CARS). The KD in prenatal valproic acid (VPA)-exposed rodents, as well as in BTBR and Mecp2 mice strains, resulted in an attenuation of some autistic-like features. The limited number of reports of improvements after treatment with the KD is insufficient to attest to the practicability of the KD as a treatment for ASD, but it is still a good indicator that this diet is a promising therapeutic option for this disorder. |
En ligne : |
http://dx.doi.org/10.1016/j.rasd.2015.08.005 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 |
in Research in Autism Spectrum Disorders > 20 (December 2015) . - p.31-38
[article] Effect of a ketogenic diet on autism spectrum disorder: A systematic review [Texte imprimé et/ou numérique] / Kamila CASTRO, Auteur ; Larissa Slongo FACCIOLI, Auteur ; Diego BARONIO, Auteur ; Carmem GOTTFRIED, Auteur ; Ingrid Schweigert PERRY, Auteur ; Rudimar DOS SANTOS RIESGO, Auteur . - p.31-38. Langues : Anglais ( eng) in Research in Autism Spectrum Disorders > 20 (December 2015) . - p.31-38
Mots-clés : |
Autistic disorder Ketogenic diet Behavioural symptoms |
Index. décimale : |
PER Périodiques |
Résumé : |
Autism spectrum disorder (ASD) is primarily characterized by impaired social interaction and communication, as well as restricted repetitive behaviours and interests. The utilization of the ketogenic diet (KD) in different neurological disorders has become a valid approach over time, and recently, it has also been advocated as a potential therapeutic for ASD. A MEDLINE, Scopus and Cochrane search was performed by two independent reviewers to investigate the relationship between ASD and the KD in humans and experimental studies. Of the eighty-one potentially relevant articles, eight articles met the inclusion criteria: three studies with animals and five studies with humans. The consistency between reviewers was ? = 0.817. In humans, the studies mainly focused on the behavioural outcomes provided by this diet and reported ameliorated behavioural symptoms via an improved score in the Childhood Autism Rating Scale (CARS). The KD in prenatal valproic acid (VPA)-exposed rodents, as well as in BTBR and Mecp2 mice strains, resulted in an attenuation of some autistic-like features. The limited number of reports of improvements after treatment with the KD is insufficient to attest to the practicability of the KD as a treatment for ASD, but it is still a good indicator that this diet is a promising therapeutic option for this disorder. |
En ligne : |
http://dx.doi.org/10.1016/j.rasd.2015.08.005 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 |
|