[article]
| Titre : |
Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Jantine A.C. BROEK, Auteur ; Paul C. GUEST, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur |
| Article en page(s) : |
p.1-8 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Autism is a neurodevelopmental disorder characterized by impaired language, communication and social skills. Although genetic studies have been carried out in this field, none of the genes identified have led to an explanation of the underlying causes. Here, we have investigated molecular alterations by proteomic profiling of post mortem brain samples from autism patients and controls. The analysis focussed on prefrontal cortex and cerebellum as previous studies have found that these two brain regions are structurally and functionally connected, and they have been implicated in autism. |
| En ligne : |
http://dx.doi.org/10.1186/2040-2392-5-41 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 |
in Molecular Autism > (July 2014) . - p.1-8
[article] Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins [Texte imprimé et/ou numérique] / Jantine A.C. BROEK, Auteur ; Paul C. GUEST, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur . - p.1-8. Langues : Anglais ( eng) in Molecular Autism > (July 2014) . - p.1-8
| Index. décimale : |
PER Périodiques |
| Résumé : |
Autism is a neurodevelopmental disorder characterized by impaired language, communication and social skills. Although genetic studies have been carried out in this field, none of the genes identified have led to an explanation of the underlying causes. Here, we have investigated molecular alterations by proteomic profiling of post mortem brain samples from autism patients and controls. The analysis focussed on prefrontal cortex and cerebellum as previous studies have found that these two brain regions are structurally and functionally connected, and they have been implicated in autism. |
| En ligne : |
http://dx.doi.org/10.1186/2040-2392-5-41 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 |
|
Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins in Molecular Autism, (July 2014)
