[article]
| Titre : |
Hypersensitive pupillary light reflex in infants at risk for autism |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Pär NYSTRÖM, Auteur ; Gustaf GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur |
| Article en page(s) : |
p.1-6 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Post mortem brain tissue data and animal modeling work indicate cholinergic disruptions in autism. Moreover, the cholinergic system plays a key role in the early neurodevelopmental processes believed to be derailed early in life in individuals with the disorder. Yet, there is no data from human infants supporting a developmentally important role of this neurotransmitter system. Because the pupillary light reflex depends largely on cholinergic synaptic transmission, we assessed this reflex in a sample of infants at risk for autism as well as infants at low (average) risk. |
| En ligne : |
http://dx.doi.org/10.1186/s13229-015-0011-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 |
in Molecular Autism > (March 2015) . - p.1-6
[article] Hypersensitive pupillary light reflex in infants at risk for autism [Texte imprimé et/ou numérique] / Pär NYSTRÖM, Auteur ; Gustaf GREDEBACK, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.1-6. Langues : Anglais ( eng) in Molecular Autism > (March 2015) . - p.1-6
| Index. décimale : |
PER Périodiques |
| Résumé : |
Post mortem brain tissue data and animal modeling work indicate cholinergic disruptions in autism. Moreover, the cholinergic system plays a key role in the early neurodevelopmental processes believed to be derailed early in life in individuals with the disorder. Yet, there is no data from human infants supporting a developmentally important role of this neurotransmitter system. Because the pupillary light reflex depends largely on cholinergic synaptic transmission, we assessed this reflex in a sample of infants at risk for autism as well as infants at low (average) risk. |
| En ligne : |
http://dx.doi.org/10.1186/s13229-015-0011-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 |
|
Hypersensitive pupillary light reflex in infants at risk for autism in Molecular Autism, (March 2015)
