[article] 
inMolecular Autism > (October 2015) . - p.1-12

Titre :	Insistence on sameness relates to increased covariance of gray matter structure in autism spectrum disorder
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Ian W. EISENBERG, Auteur ; Gregory L. WALLACE, Auteur ; Lauren KENWORTHY, Auteur ; Stephen J. GOTTS, Auteur ; Alex MARTIN, Auteur
Article en page(s) :	p.1-12
Langues :	Anglais (eng)
Index. décimale :	PER Périodiques
Résumé :	Autism spectrum disorder (ASD) is characterized by atypical development of cortical and subcortical gray matter volume. Subcortical structural changes have been associated with restricted and repetitive behavior (RRB), a core component of ASD. Behavioral studies have identified insistence on sameness (IS) as a separable RRB dimension prominent in high-functioning ASD, though no simple brain-behavior relationship has emerged. Structural covariance, a measure of morphological coupling among brain regions using magnetic resonance imaging (MRI), has proven an informative measure of anatomical relationships in typical development and neurodevelopmental disorders. In this study, we use this measure to characterize the relationship between brain structure and IS.
En ligne :	http://dx.doi.org/10.1186/s13229-015-0047-7
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

[article] Insistence on sameness relates to increased covariance of gray matter structure in autism spectrum disorder [Texte imprimé et/ou numérique] / Ian W. EISENBERG, Auteur ; Gregory L. WALLACE, Auteur ; Lauren KENWORTHY, Auteur ; Stephen J. GOTTS, Auteur ; Alex MARTIN, Auteur . - p.1-12.
Langues : Anglais (eng)
in Molecular Autism > (October 2015) . - p.1-12

Index. décimale :	PER Périodiques
Résumé :	Autism spectrum disorder (ASD) is characterized by atypical development of cortical and subcortical gray matter volume. Subcortical structural changes have been associated with restricted and repetitive behavior (RRB), a core component of ASD. Behavioral studies have identified insistence on sameness (IS) as a separable RRB dimension prominent in high-functioning ASD, though no simple brain-behavior relationship has emerged. Structural covariance, a measure of morphological coupling among brain regions using magnetic resonance imaging (MRI), has proven an informative measure of anatomical relationships in typical development and neurodevelopmental disorders. In this study, we use this measure to characterize the relationship between brain structure and IS.
En ligne :	http://dx.doi.org/10.1186/s13229-015-0047-7
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277