[article] 
inJournal of Child Psychology and Psychiatry > 48-12 (December 2007) . - p.1160–1173

Titre :	Research Review: Genetic vulnerability or differential susceptibility in child development: the case of attachment
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Marian J. BAKERMANS-KRANENBURG, Auteur ; Marinus H. VAN IJZENDOORN, Auteur
Année de publication :	2007
Article en page(s) :	p.1160–1173
Langues :	Anglais (eng)
Mots-clés :	Attachment gene–environment-interaction differential-susceptibility disorganized-attachment dopamine behavior-problems genetics
Index. décimale :	PER Périodiques
Résumé :	Gene–environment interactions interpreted in terms of differential susceptibility may play a large part in the explanation of individual differences in human development. Reviewing studies on the behavioral and molecular genetics of attachment, we present evidence for interactions between genetic and environmental factors explaining individual differences in attachment security and disorganization. In particular, the DRD4 7-repeat polymorphism seems associated with an increased risk for disorganized attachment, but only when combined with environmental risk. Gene–environment (G × E) interactions may be interpreted as genetic vulnerability or differential susceptibility. We found support for the differential susceptibility hypothesis predicting not only more negative outcomes for susceptible children in unfavorable environments, but also positive outcomes for susceptible children in favorable environments.
En ligne :	http://dx.doi.org/10.1111/j.1469-7610.2007.01801.x
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309

[article] Research Review: Genetic vulnerability or differential susceptibility in child development: the case of attachment [Texte imprimé et/ou numérique] / Marian J. BAKERMANS-KRANENBURG, Auteur ; Marinus H. VAN IJZENDOORN, Auteur . - 2007 . - p.1160–1173.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 48-12 (December 2007) . - p.1160–1173

Mots-clés :	Attachment gene–environment-interaction differential-susceptibility disorganized-attachment dopamine behavior-problems genetics
Index. décimale :	PER Périodiques
Résumé :	Gene–environment interactions interpreted in terms of differential susceptibility may play a large part in the explanation of individual differences in human development. Reviewing studies on the behavioral and molecular genetics of attachment, we present evidence for interactions between genetic and environmental factors explaining individual differences in attachment security and disorganization. In particular, the DRD4 7-repeat polymorphism seems associated with an increased risk for disorganized attachment, but only when combined with environmental risk. Gene–environment (G × E) interactions may be interpreted as genetic vulnerability or differential susceptibility. We found support for the differential susceptibility hypothesis predicting not only more negative outcomes for susceptible children in unfavorable environments, but also positive outcomes for susceptible children in favorable environments.
En ligne :	http://dx.doi.org/10.1111/j.1469-7610.2007.01801.x
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309