[article] 
inJournal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3620-3633

Titre :	Symptoms of Autism Spectrum Disorder (ASD) in Individuals with Mucopolysaccharide Disease Type III (Sanfilippo Syndrome): A Systematic Review
Type de document :	Texte imprimé et/ou numérique
Auteurs :	C. WOLFENDEN, Auteur ; A. WITTKOWSKI, Auteur ; D. J. HARE, Auteur
Article en page(s) :	p.3620-3633
Langues :	Anglais (eng)
Mots-clés :	Asd  Behavioural difficulties  Developmental disorder  Lysosomal storage disorder  Mucopolysacchardosis  Speech/language delay
Index. décimale :	PER Périodiques
Résumé :	The prevalence of autism spectrum disorder (ASD) in many genetic disorders is well documented but not as yet in Mucopolysaccharidosis type III (MPS III). MPS III is a recessively inherited metabolic disorder and evidence suggests that symptoms of ASD present in MPS III. This systematic review examined the extant literature on the symptoms of ASD in MPS III and quality assessed a total of 16 studies. Results indicated that difficulties within speech, language and communication consistent with ASD were present in MPS III, whilst repetitive and restricted behaviours and interests were less widely reported. The presence of ASD-like symptoms can result in late diagnosis or misdiagnosis of MPS III and prevent opportunities for genetic counselling and the provision of treatments.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3262-6
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325

[article] Symptoms of Autism Spectrum Disorder (ASD) in Individuals with Mucopolysaccharide Disease Type III (Sanfilippo Syndrome): A Systematic Review [Texte imprimé et/ou numérique] / C. WOLFENDEN, Auteur ; A. WITTKOWSKI, Auteur ; D. J. HARE, Auteur . - p.3620-3633.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3620-3633

Mots-clés :	Asd  Behavioural difficulties  Developmental disorder  Lysosomal storage disorder  Mucopolysacchardosis  Speech/language delay
Index. décimale :	PER Périodiques
Résumé :	The prevalence of autism spectrum disorder (ASD) in many genetic disorders is well documented but not as yet in Mucopolysaccharidosis type III (MPS III). MPS III is a recessively inherited metabolic disorder and evidence suggests that symptoms of ASD present in MPS III. This systematic review examined the extant literature on the symptoms of ASD in MPS III and quality assessed a total of 16 studies. Results indicated that difficulties within speech, language and communication consistent with ASD were present in MPS III, whilst repetitive and restricted behaviours and interests were less widely reported. The presence of ASD-like symptoms can result in late diagnosis or misdiagnosis of MPS III and prevent opportunities for genetic counselling and the provision of treatments.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3262-6
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325