[article]
| Titre : |
Editorial: Can dysregulated myelination be linked to ADHD pathogenesis and persistence? |
| Type de document : |
texte imprimé |
| Auteurs : |
K. P. LESCH, Auteur |
| Article en page(s) : |
p.229-231 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Converging evidence from new epidemiologic, genetic, epigenetic, neuroimaging, and experimental model findings are further refining a long-standing concept, regarding the underlying neurobiology of attention-deficit/hyperactivity disorder (ADHD): that ADHD onset and its persistence into adulthood are the result of dysregulated myelination and associated alterations in neuronal plasticity - linked to disrupted brain maturation and the persistence of cognitive and emotional impairments across the life span. If supported by further work, this concept represents a pathophysiologic mechanism amenable to therapeutic intervention. |
| En ligne : |
https://dx.doi.org/10.1111/jcpp.13031 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385 |
in Journal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.229-231
[article] Editorial: Can dysregulated myelination be linked to ADHD pathogenesis and persistence? [texte imprimé] / K. P. LESCH, Auteur . - p.229-231. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.229-231
| Index. décimale : |
PER Périodiques |
| Résumé : |
Converging evidence from new epidemiologic, genetic, epigenetic, neuroimaging, and experimental model findings are further refining a long-standing concept, regarding the underlying neurobiology of attention-deficit/hyperactivity disorder (ADHD): that ADHD onset and its persistence into adulthood are the result of dysregulated myelination and associated alterations in neuronal plasticity - linked to disrupted brain maturation and the persistence of cognitive and emotional impairments across the life span. If supported by further work, this concept represents a pathophysiologic mechanism amenable to therapeutic intervention. |
| En ligne : |
https://dx.doi.org/10.1111/jcpp.13031 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385 |
|  |
Editorial: Can dysregulated myelination be linked to ADHD pathogenesis and persistence? in Journal of Child Psychology and Psychiatry, 60-3 (March 2019)
