[article] 
inJournal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.632-643

Titre :	Evaluation of Appetite-Regulating Hormones ?n Young Children with Autism Spectrum Disorder
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Ça?la ÇELIKKOL SADIÇ, Auteur ; Ayhan BILGIC, Auteur ; ?brahim KILINÇ, Auteur ; Mehmet Burhan OFLAZ, Auteur ; Tamer BAYSAL, Auteur
Article en page(s) :	p.632-643
Langues :	Anglais (eng)
Mots-clés :	Autism  Early childhood  Ghrelin  Leptin  Nesfatin-1  Neuropeptide Y
Index. décimale :	PER Périodiques
Résumé :	This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.
En ligne :	http://dx.doi.org/10.1007/s10803-020-04579-0
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440

[article] Evaluation of Appetite-Regulating Hormones ?n Young Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Ça?la ÇELIKKOL SADIÇ, Auteur ; Ayhan BILGIC, Auteur ; ?brahim KILINÇ, Auteur ; Mehmet Burhan OFLAZ, Auteur ; Tamer BAYSAL, Auteur . - p.632-643.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.632-643

Mots-clés :	Autism  Early childhood  Ghrelin  Leptin  Nesfatin-1  Neuropeptide Y
Index. décimale :	PER Périodiques
Résumé :	This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.
En ligne :	http://dx.doi.org/10.1007/s10803-020-04579-0
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440