Autism, Personality Pathology, and the Neural Response to Rewards / Sarah B. BARKLEY in Journal of Autism and Developmental Disorders, 56-8 (August 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-8 (August 2026) . - p.3168-3179 Titre : Autism, Personality Pathology, and the Neural Response to Rewards Type de document : texte imprimé Auteurs : Sarah B. BARKLEY, Auteur ; Talena DAY, Auteur ; Matthew D. LERNER, Auteur ; Brady D. NELSON, Auteur Article en page(s) : p.3168-3179 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The autism social motivation hypothesis suggests that diminished reward value of social stimuli contributes to deficits in social motivation. Research indicates that autistic individuals show decreased neural responding to both social and non-social reward, suggesting domain-general reward system differences. However, autism is heterogenous with extensive co-occurring psychopathology, and the autism phenotype may not be the best way to understand its relationship with neural reward response. Autism has been associated with normative and pathological personality domains that may better represent the heterogeneity and comorbidity of autism. The present study examined associations between autism traits, pathological personality, and the neural response to multiple reward types. The sample included 18-33-year-old undergraduates who completed monetary, social, and restricted interests reward tasks while we recorded electroencephalography to measure the reward positivity (RewP), an event-related potential indicator of reward sensitivity. Participants completed self-report measures of autism traits and the pathological personality traits negative emotionality, detachment, and anankastia. Autism traits were not directly related to the RewP but were positively associated with pathological personality dimensions. Across all reward tasks, negative emotionality was related to a larger RewP while detachment and anankastia were related to a smaller RewP. All three pathological personality dimensions mediated the relationship between autism traits and the RewP. The present study suggests that autism and neural reward response is at least partially mediated by comorbid psychopathology. Moreover, the results are inconsistent with the social motivation hypothesis and instead suggest that autism is linked to domain-general neural response to rewards. En ligne : https://doi.org/10.1007/s10803-025-06789-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Autism, Personality Pathology, and the Neural Response to Rewards [texte imprimé] / Sarah B. BARKLEY, Auteur ; Talena DAY, Auteur ; Matthew D. LERNER, Auteur ; Brady D. NELSON, Auteur . - p.3168-3179. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-8 (August 2026) . - p.3168-3179 Index. décimale : PER Périodiques Résumé : The autism social motivation hypothesis suggests that diminished reward value of social stimuli contributes to deficits in social motivation. Research indicates that autistic individuals show decreased neural responding to both social and non-social reward, suggesting domain-general reward system differences. However, autism is heterogenous with extensive co-occurring psychopathology, and the autism phenotype may not be the best way to understand its relationship with neural reward response. Autism has been associated with normative and pathological personality domains that may better represent the heterogeneity and comorbidity of autism. The present study examined associations between autism traits, pathological personality, and the neural response to multiple reward types. The sample included 18-33-year-old undergraduates who completed monetary, social, and restricted interests reward tasks while we recorded electroencephalography to measure the reward positivity (RewP), an event-related potential indicator of reward sensitivity. Participants completed self-report measures of autism traits and the pathological personality traits negative emotionality, detachment, and anankastia. Autism traits were not directly related to the RewP but were positively associated with pathological personality dimensions. Across all reward tasks, negative emotionality was related to a larger RewP while detachment and anankastia were related to a smaller RewP. All three pathological personality dimensions mediated the relationship between autism traits and the RewP. The present study suggests that autism and neural reward response is at least partially mediated by comorbid psychopathology. Moreover, the results are inconsistent with the social motivation hypothesis and instead suggest that autism is linked to domain-general neural response to rewards. En ligne : https://doi.org/10.1007/s10803-025-06789-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Childhood anhedonia symptoms and stressful life events predict the development of reward-related brain activity across adolescence / A.K. SZENCZY in Development and Psychopathology, 37-2 (May 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-2 (May 2025) . - p.825-835 Titre : Childhood anhedonia symptoms and stressful life events predict the development of reward-related brain activity across adolescence Type de document : texte imprimé Auteurs : A.K. SZENCZY, Auteur ; E.M. ADAMS, Auteur ; M.T. HAWES, Auteur ; J. ANATALA, Auteur ; K. GAIR, Auteur ; Daniel N. KLEIN, Auteur ; Greg HAJCAK, Auteur ; Brady D. NELSON, Auteur Article en page(s) : p.825-835 Langues : Anglais (eng) Mots-clés : Adolescence  depression  reward positivity  stress Index. décimale : PER Périodiques Résumé : The reward positivity (RewP) is an event-related potential that indexes reinforcement learning and reward system activation. The RewP has been shown to increase across adolescence; however, most studies have examined the RewP across two assessments, and no studies have examined within-person changes across adolescence into young adulthood. Moreover, the RewP has been identified as a neurobiological risk factor for adolescent-onset depression, but it is unclear whether childhood psychosocial risk factors might predict RewP development across adolescence. In a sample of 317 8- to 14-year-old girls (Mage = 12.4, SD = 1.8), the present study examined self-report measures of depression symptoms and stressful life events at baseline and the ?RewP during the doors guessing task across three timepoints. Growth modeling indicated that, across all participants, the ?RewP did not demonstrate linear change across adolescence. However, baseline anhedonia symptoms predicted within-person changes in the ?RewP, such that individuals with low anhedonia symptoms demonstrated a linear increase in the ?RewP, but individuals with high anhedonia symptoms had no change in the ?RewP across adolescence. Similar patterns were observed for stressful life events. The present study suggests that childhood risk factors impact the development of reward-related brain activity, which might subsequently increase risk for psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579424000701 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552 [article] Childhood anhedonia symptoms and stressful life events predict the development of reward-related brain activity across adolescence [texte imprimé] / A.K. SZENCZY, Auteur ; E.M. ADAMS, Auteur ; M.T. HAWES, Auteur ; J. ANATALA, Auteur ; K. GAIR, Auteur ; Daniel N. KLEIN, Auteur ; Greg HAJCAK, Auteur ; Brady D. NELSON, Auteur . - p.825-835. Langues : Anglais (eng) in Development and Psychopathology > 37-2 (May 2025) . - p.825-835 Mots-clés : Adolescence  depression  reward positivity  stress Index. décimale : PER Périodiques Résumé : The reward positivity (RewP) is an event-related potential that indexes reinforcement learning and reward system activation. The RewP has been shown to increase across adolescence; however, most studies have examined the RewP across two assessments, and no studies have examined within-person changes across adolescence into young adulthood. Moreover, the RewP has been identified as a neurobiological risk factor for adolescent-onset depression, but it is unclear whether childhood psychosocial risk factors might predict RewP development across adolescence. In a sample of 317 8- to 14-year-old girls (Mage = 12.4, SD = 1.8), the present study examined self-report measures of depression symptoms and stressful life events at baseline and the ?RewP during the doors guessing task across three timepoints. Growth modeling indicated that, across all participants, the ?RewP did not demonstrate linear change across adolescence. However, baseline anhedonia symptoms predicted within-person changes in the ?RewP, such that individuals with low anhedonia symptoms demonstrated a linear increase in the ?RewP, but individuals with high anhedonia symptoms had no change in the ?RewP across adolescence. Similar patterns were observed for stressful life events. The present study suggests that childhood risk factors impact the development of reward-related brain activity, which might subsequently increase risk for psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579424000701 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=552

Childhood psychopathology predicts development of error-related brain activity across adolescence / Elise M. ADAMS in Development and Psychopathology, 37-5 (December 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-5 (December 2025) . - p.2795-2805 Titre : Childhood psychopathology predicts development of error-related brain activity across adolescence Type de document : texte imprimé Auteurs : Elise M. ADAMS, Auteur ; Aline K. SZENCZY, Auteur ; Mariah T. HAWES, Auteur ; Alexandria MEYER, Auteur ; Greg HAJCAK, Auteur ; Brady D. NELSON, Auteur Article en page(s) : p.2795-2805 Langues : Anglais (eng) Mots-clés : Adolescence  anxiety  depression  error-related negativity Index. décimale : PER Périodiques Résumé : Cross-sectional and longitudinal evidence indicates that the error-related negativity (ERN) increases across adolescence. However, there are no longitudinal studies of ERN development which traverse all of adolescence. In addition, anxiety (e.g., generalized and social anxiety) and depression have been associated with a larger and smaller ERN, respectively, but it is unknown whether childhood psychopathology is associated with adolescent development of the ERN. In the present study, 317 8 to 14-year-old girls completed a flanker task at baseline and approximately 2-year and 5-year follow-ups. Multilevel growth modeling was used to examine ERN trajectory across adolescence and test whether self-reported childhood generalized anxiety, social anxiety, and depression symptoms at baseline predicted ERN trajectory. On average, the ERN demonstrated a linear increase from late childhood to early adulthood. Additionally, participants with high baseline anxiety (generalized anxiety, social anxiety) and low depression symptoms had the steepest ERN trajectory across adolescence. The present study provides longitudinal support for an increase in the ERN spanning adolescence and demonstrates that childhood psychopathology is associated with error-related neural development into early adulthood. En ligne : https://dx.doi.org/10.1017/S0954579425100370 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Childhood psychopathology predicts development of error-related brain activity across adolescence [texte imprimé] / Elise M. ADAMS, Auteur ; Aline K. SZENCZY, Auteur ; Mariah T. HAWES, Auteur ; Alexandria MEYER, Auteur ; Greg HAJCAK, Auteur ; Brady D. NELSON, Auteur . - p.2795-2805. Langues : Anglais (eng) in Development and Psychopathology > 37-5 (December 2025) . - p.2795-2805 Mots-clés : Adolescence  anxiety  depression  error-related negativity Index. décimale : PER Périodiques Résumé : Cross-sectional and longitudinal evidence indicates that the error-related negativity (ERN) increases across adolescence. However, there are no longitudinal studies of ERN development which traverse all of adolescence. In addition, anxiety (e.g., generalized and social anxiety) and depression have been associated with a larger and smaller ERN, respectively, but it is unknown whether childhood psychopathology is associated with adolescent development of the ERN. In the present study, 317 8 to 14-year-old girls completed a flanker task at baseline and approximately 2-year and 5-year follow-ups. Multilevel growth modeling was used to examine ERN trajectory across adolescence and test whether self-reported childhood generalized anxiety, social anxiety, and depression symptoms at baseline predicted ERN trajectory. On average, the ERN demonstrated a linear increase from late childhood to early adulthood. Additionally, participants with high baseline anxiety (generalized anxiety, social anxiety) and low depression symptoms had the steepest ERN trajectory across adolescence. The present study provides longitudinal support for an increase in the ERN spanning adolescence and demonstrates that childhood psychopathology is associated with error-related neural development into early adulthood. En ligne : https://dx.doi.org/10.1017/S0954579425100370 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder / Cara M. KEIFER in Journal of Autism and Developmental Disorders, 49-12 (December 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-12 (December 2019) . - p.5009-5022 Titre : Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Cara M. KEIFER, Auteur ; Kathryn M. HAUSCHILD, Auteur ; Brady D. NELSON, Auteur ; Greg HAJCAK, Auteur ; Matthew D. LERNER, Auteur Article en page(s) : p.5009-5022 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Erp  Emotion processing  Lpp  P300  Social cognition Index. décimale : PER Périodiques Résumé : Despite evidence suggesting differences in early event-related potential (ERP) responses to social emotional stimuli, little is known about later stage ERP contributions to social emotional processing in individuals with autism spectrum disorder (ASD). Adults with and without ASD completed a facial emotion recognition task involving stimuli that varied by emotional intensity while electroencephalograms were recorded. Principal components analysis was used to examine P300 and late positive potential (LPP) modulation by emotional intensity. Results indicated that greater ASD symptomatology evinced heightened P300 to high relative to low intensity faces, then heightened LPP to low relative to high intensity faces. Findings suggest that adults with greater ASD symptomatology may demonstrate a lag in engagement in elaborative processing of low intensity faces. En ligne : http://dx.doi.org/10.1007/s10803-019-04207-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=411 [article] Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder [texte imprimé] / Cara M. KEIFER, Auteur ; Kathryn M. HAUSCHILD, Auteur ; Brady D. NELSON, Auteur ; Greg HAJCAK, Auteur ; Matthew D. LERNER, Auteur . - p.5009-5022. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-12 (December 2019) . - p.5009-5022 Mots-clés : Autism spectrum disorder  Erp  Emotion processing  Lpp  P300  Social cognition Index. décimale : PER Périodiques Résumé : Despite evidence suggesting differences in early event-related potential (ERP) responses to social emotional stimuli, little is known about later stage ERP contributions to social emotional processing in individuals with autism spectrum disorder (ASD). Adults with and without ASD completed a facial emotion recognition task involving stimuli that varied by emotional intensity while electroencephalograms were recorded. Principal components analysis was used to examine P300 and late positive potential (LPP) modulation by emotional intensity. Results indicated that greater ASD symptomatology evinced heightened P300 to high relative to low intensity faces, then heightened LPP to low relative to high intensity faces. Findings suggest that adults with greater ASD symptomatology may demonstrate a lag in engagement in elaborative processing of low intensity faces. En ligne : http://dx.doi.org/10.1007/s10803-019-04207-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=411

Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers / Stewart A. SHANKMAN in Development and Psychopathology, 23-2 (May 2011)  

Public ISBD [article]  inDevelopment and Psychopathology > 23-2 (May 2011) . - p.551-562 Titre : Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers Type de document : texte imprimé Auteurs : Stewart A. SHANKMAN, Auteur ; Daniel N. KLEIN, Auteur ; Dana C. TORPEY, Auteur ; Thomas M. OLINO, Auteur ; Margaret DYSON, Auteur ; Jiyon KIM, Auteur ; C. Emily DURBIN, Auteur ; Brady D. NELSON, Auteur ; Craig E. TENKE, Auteur Année de publication : 2011 Article en page(s) : p.551-562 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Researchers have long been interested in whether particular temperamental traits in childhood connote risk for depressive disorders. For example, children characterized as having high negative emotionality (NE; sadness, fear, anger) and low positive emotionality (PE; anhedonia, listlessness, and lack of enthusiasm) are hypothesized to be at risk for depression. Few studies, however, have examined whether (and how) these two temperamental dimensions interact to confer risk. In a sample of 329 preschoolers, the present study addressed this question by examining the relation between PE and NE and asymmetry in resting EEG activity in frontal and posterior regions, which are putative biomarkers for depression. Using a laboratory battery to define temperament, we found an interaction of PE and NE on posterior asymmetry. Specifically, when PE was high, NE was associated with greater relative right activity. When PE was low, NE was not related to posterior asymmetry. These results were driven by differences in EEG activity in right posterior regions, an area associated with emotional processing and arousal, and were specific to girls. We found no relation between temperament and frontal asymmetry. These findings suggest that, at least for girls, PE and NE may have an interactive effect on risk for depression. En ligne : http://dx.doi.org/10.1017/S0954579411000022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers [texte imprimé] / Stewart A. SHANKMAN, Auteur ; Daniel N. KLEIN, Auteur ; Dana C. TORPEY, Auteur ; Thomas M. OLINO, Auteur ; Margaret DYSON, Auteur ; Jiyon KIM, Auteur ; C. Emily DURBIN, Auteur ; Brady D. NELSON, Auteur ; Craig E. TENKE, Auteur . - 2011 . - p.551-562. Langues : Anglais (eng) in Development and Psychopathology > 23-2 (May 2011) . - p.551-562 Index. décimale : PER Périodiques Résumé : Researchers have long been interested in whether particular temperamental traits in childhood connote risk for depressive disorders. For example, children characterized as having high negative emotionality (NE; sadness, fear, anger) and low positive emotionality (PE; anhedonia, listlessness, and lack of enthusiasm) are hypothesized to be at risk for depression. Few studies, however, have examined whether (and how) these two temperamental dimensions interact to confer risk. In a sample of 329 preschoolers, the present study addressed this question by examining the relation between PE and NE and asymmetry in resting EEG activity in frontal and posterior regions, which are putative biomarkers for depression. Using a laboratory battery to define temperament, we found an interaction of PE and NE on posterior asymmetry. Specifically, when PE was high, NE was associated with greater relative right activity. When PE was low, NE was not related to posterior asymmetry. These results were driven by differences in EEG activity in right posterior regions, an area associated with emotional processing and arousal, and were specific to girls. We found no relation between temperament and frontal asymmetry. These findings suggest that, at least for girls, PE and NE may have an interactive effect on risk for depression. En ligne : http://dx.doi.org/10.1017/S0954579411000022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females / Alexandria MEYER in Journal of Child Psychology and Psychiatry, 59-11 (November 2018)  

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Parenting style moderates the effects of exposure to natural disaster-related stress on the neural development of reactivity to threat and reward in children / Ellen M. KESSEL in Development and Psychopathology, 31-4 (October 2019)  

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