[article]
Titre : |
Pediatric depression: is there evidence to improve evidence-based treatments? |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
David A. BRENT, Auteur ; Fadi T. MAALOUF, Auteur |
Année de publication : |
2009 |
Article en page(s) : |
p.143-152 |
Langues : |
Anglais (eng) |
Mots-clés : |
Depression cognition development treatment intermediate-phenotype biomarker |
Index. décimale : |
PER Périodiques |
Résumé : |
Although there have been advances in our ability to treat child and adolescent depression, use of evidence-based treatments still results in many patients with residual symptoms. Advances in our understanding of cognitive, emotional, and ecological aspects of early-onset depression have the potential to lead to improvements in the assessment and treatment of depression. A search for endophenotypes, i.e., traits that are related to depression, mediate the familial transmission of depression, and are genetically determined, may help in understanding etiology and in personalizing treatment. However, advances in treatment may also come from the identification of biomarkers, i.e., modifiable neurocognitive, physiological, or biochemical indices that are correlated with, or mediate, treatment outcome. More effective treatments may emerge from being able to personalize interventions to the patient's cognitive, emotional, and developmental profile. |
En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2008.02037.x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 |
in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.143-152
[article] Pediatric depression: is there evidence to improve evidence-based treatments? [Texte imprimé et/ou numérique] / David A. BRENT, Auteur ; Fadi T. MAALOUF, Auteur . - 2009 . - p.143-152. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 50-1-2 (January/February 2009) . - p.143-152
Mots-clés : |
Depression cognition development treatment intermediate-phenotype biomarker |
Index. décimale : |
PER Périodiques |
Résumé : |
Although there have been advances in our ability to treat child and adolescent depression, use of evidence-based treatments still results in many patients with residual symptoms. Advances in our understanding of cognitive, emotional, and ecological aspects of early-onset depression have the potential to lead to improvements in the assessment and treatment of depression. A search for endophenotypes, i.e., traits that are related to depression, mediate the familial transmission of depression, and are genetically determined, may help in understanding etiology and in personalizing treatment. However, advances in treatment may also come from the identification of biomarkers, i.e., modifiable neurocognitive, physiological, or biochemical indices that are correlated with, or mediate, treatment outcome. More effective treatments may emerge from being able to personalize interventions to the patient's cognitive, emotional, and developmental profile. |
En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2008.02037.x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=695 |
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