[article] 
inJournal of Autism and Developmental Disorders > 39-4 (April 2009) . - p.619-634

Titre :	Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Lonnie L. SEARS, Auteur ; Ayman S. EL-BAZ, Auteur ; Grace MATHAI, Auteur ; Joshua M. BARUTH, Auteur
Année de publication :	2009
Article en page(s) :	p.619-634
Langues :	Anglais (eng)
Mots-clés :	Autism Minicolumns Event-related-potentials Electroencephalography Gamma-frequencies
Index. décimale :	PER Périodiques
Résumé :	Previous studies by our group suggest that the neuropathology of autism is characterized by a disturbance of cortical modularity. In this model a decrease in the peripheral neuropil space of affected minicolumns provides for an inhibitory deficit and a readjustment in their signal to noise bias during information processing. In this study we proposed using low frequency transcranial magnetic stimulation (rTMS) as a way increasing the surround inhibition of minicolumns in autism. Thirteen patients (ADOS and ADI-R diagnized) and equal number of controls participated in the study. Repetitive TMS was delivered at 0.5 Hz, 2 times per week for 3 weeks. Outcome measures based on event-related potentials (ERP), induced gamma activity, and behavioral measures showed significant post-TMS improvement. The results suggest that rTMS offers a potential therapeutic intervention for autism.
En ligne :	http://dx.doi.org/10.1007/s10803-008-0662-7
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=706

[article] Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism [Texte imprimé et/ou numérique] / Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Lonnie L. SEARS, Auteur ; Ayman S. EL-BAZ, Auteur ; Grace MATHAI, Auteur ; Joshua M. BARUTH, Auteur . - 2009 . - p.619-634.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 39-4 (April 2009) . - p.619-634

Mots-clés :	Autism Minicolumns Event-related-potentials Electroencephalography Gamma-frequencies
Index. décimale :	PER Périodiques
Résumé :	Previous studies by our group suggest that the neuropathology of autism is characterized by a disturbance of cortical modularity. In this model a decrease in the peripheral neuropil space of affected minicolumns provides for an inhibitory deficit and a readjustment in their signal to noise bias during information processing. In this study we proposed using low frequency transcranial magnetic stimulation (rTMS) as a way increasing the surround inhibition of minicolumns in autism. Thirteen patients (ADOS and ADI-R diagnized) and equal number of controls participated in the study. Repetitive TMS was delivered at 0.5 Hz, 2 times per week for 3 weeks. Outcome measures based on event-related potentials (ERP), induced gamma activity, and behavioral measures showed significant post-TMS improvement. The results suggest that rTMS offers a potential therapeutic intervention for autism.
En ligne :	http://dx.doi.org/10.1007/s10803-008-0662-7
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=706