[article]
Titre : |
Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur |
Article en page(s) : |
p.719-730 |
Langues : |
Anglais (eng) |
Mots-clés : |
Thyroid Thyroid stimulating hormone Autism Pregnancy Developmental delay |
Index. décimale : |
PER Périodiques |
Résumé : |
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). |
En ligne : |
http://dx.doi.org/10.1007/s10803-014-2227-2 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 |
in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730
[article] Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur . - p.719-730. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730
Mots-clés : |
Thyroid Thyroid stimulating hormone Autism Pregnancy Developmental delay |
Index. décimale : |
PER Périodiques |
Résumé : |
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). |
En ligne : |
http://dx.doi.org/10.1007/s10803-014-2227-2 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 |
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