Dépouillements

Editorial: 2014 in Review / Fred R. VOLKMAR in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.613-625 Titre : Editorial: 2014 in Review Type de document : Texte imprimé et/ou numérique Auteurs : Fred R. VOLKMAR, Auteur Article en page(s) : p.613-625 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-015-2382-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Editorial: 2014 in Review [Texte imprimé et/ou numérique] / Fred R. VOLKMAR, Auteur . - p.613-625. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.613-625 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-015-2382-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

A Cross-Sectional Cohort Study of a Large, Statewide Medicaid Home and Community-Based Services Autism Waiver Program / Karen Goldrich ESKOW in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.626-635 Titre : A Cross-Sectional Cohort Study of a Large, Statewide Medicaid Home and Community-Based Services Autism Waiver Program Type de document : Texte imprimé et/ou numérique Auteurs : Karen Goldrich ESKOW, Auteur ; Gregory S. CHASSON, Auteur ; Jean Ann SUMMERS, Auteur Article en page(s) : p.626-635 Langues : Anglais (eng) Mots-clés : Autism services  Medicaid  Home and community-based services waiver  Family quality of life Index. décimale : PER Périodiques Résumé : State-specific 1915(c) Medicaid Home and Community-Based Services waiver programs have become central in the provision of services specifically tailored to children with autism spectrum disorders (ASD). Using propensity score matching, 130 families receiving waiver services for a child with ASD were matched with and compared to 130 families waiting on the registry (i.e., control group). Results indicate that participants in the waiver group reported more improvement in independent living skills and family quality of life over the last year compared to those on the registry. More frequent intensive individual support services and therapeutic integration were statistically predictive of improvement in a variety of domains. The results suggest that the waiver program may be promising for improving child and family functioning. En ligne : http://dx.doi.org/10.1007/s10803-014-2217-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] A Cross-Sectional Cohort Study of a Large, Statewide Medicaid Home and Community-Based Services Autism Waiver Program [Texte imprimé et/ou numérique] / Karen Goldrich ESKOW, Auteur ; Gregory S. CHASSON, Auteur ; Jean Ann SUMMERS, Auteur . - p.626-635. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.626-635 Mots-clés : Autism services  Medicaid  Home and community-based services waiver  Family quality of life Index. décimale : PER Périodiques Résumé : State-specific 1915(c) Medicaid Home and Community-Based Services waiver programs have become central in the provision of services specifically tailored to children with autism spectrum disorders (ASD). Using propensity score matching, 130 families receiving waiver services for a child with ASD were matched with and compared to 130 families waiting on the registry (i.e., control group). Results indicate that participants in the waiver group reported more improvement in independent living skills and family quality of life over the last year compared to those on the registry. More frequent intensive individual support services and therapeutic integration were statistically predictive of improvement in a variety of domains. The results suggest that the waiver program may be promising for improving child and family functioning. En ligne : http://dx.doi.org/10.1007/s10803-014-2217-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

The Impact of the Medical Home on Access to Care for Children with Autism Spectrum Disorders / Nancy C. CHEAK-ZAMORA in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.636-644 Titre : The Impact of the Medical Home on Access to Care for Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Nancy C. CHEAK-ZAMORA, Auteur ; Janet E. FARMER, Auteur Article en page(s) : p.636-644 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Delivery of health care  Unmet needs  Medical home Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) experience difficulty accessing health care services. Using parent-reported data from the 2009–2010 National Survey of Children with Special Health Care Needs, we examined whether having a medical home reduces unmet need for specialty care services for children with ASD (n = 3,055). Descriptive statistics and Chi square tests identified sample characteristics and examined the relationship between unmet needs and a standardized measure of medical home. Logistic regression models explored the individual impact of demographic, condition-specific and medical home variables on unmet need. Parents reported that nearly all children had a need for specialty services, 36 % had an unmet need, and 23.9 % had a medical home. Children who had fewer unmet needs were more likely to have received family-centered and coordinated care through a medical home, and this relationship remained significant even when demographic and condition-specific variables were taken into account. These findings suggest ways to improve access to care for children with ASD through enhanced family-centered and coordinated care within the medical home. En ligne : http://dx.doi.org/10.1007/s10803-014-2218-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] The Impact of the Medical Home on Access to Care for Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Nancy C. CHEAK-ZAMORA, Auteur ; Janet E. FARMER, Auteur . - p.636-644. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.636-644 Mots-clés : Autism spectrum disorder  Delivery of health care  Unmet needs  Medical home Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) experience difficulty accessing health care services. Using parent-reported data from the 2009–2010 National Survey of Children with Special Health Care Needs, we examined whether having a medical home reduces unmet need for specialty care services for children with ASD (n = 3,055). Descriptive statistics and Chi square tests identified sample characteristics and examined the relationship between unmet needs and a standardized measure of medical home. Logistic regression models explored the individual impact of demographic, condition-specific and medical home variables on unmet need. Parents reported that nearly all children had a need for specialty services, 36 % had an unmet need, and 23.9 % had a medical home. Children who had fewer unmet needs were more likely to have received family-centered and coordinated care through a medical home, and this relationship remained significant even when demographic and condition-specific variables were taken into account. These findings suggest ways to improve access to care for children with ASD through enhanced family-centered and coordinated care within the medical home. En ligne : http://dx.doi.org/10.1007/s10803-014-2218-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Simplex and Multiplex Stratification in ASD and ADHD Families: A Promising Approach for Identifying Overlapping and Unique Underpinnings of ASD and ADHD? / Anoek M. OERLEMANS in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.645-657 Titre : Simplex and Multiplex Stratification in ASD and ADHD Families: A Promising Approach for Identifying Overlapping and Unique Underpinnings of ASD and ADHD? Type de document : Texte imprimé et/ou numérique Auteurs : Anoek M. OERLEMANS, Auteur ; Catharina A. HARTMAN, Auteur ; Yvette G. E. DE BRUIJN, Auteur ; Daphne J. VAN STEIJN, Auteur ; Barbara FRANKE, Auteur ; Jan K. BUITELAAR, Auteur ; Nanda N. ROMMELSE, Auteur Article en page(s) : p.645-657 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD)  Attention-deficit/hyperactivity disorder (ADHD)  Simplex–multiplex stratification  Family  Unaffected relative Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are highly heterogeneous neuropsychiatric disorders, that frequently co-occur. This study examined whether stratification into single-incidence (SPX) and multi-incidence (MPX) is helpful in (a) parsing heterogeneity and (b) detecting overlapping and unique underpinnings of the disorders. ASD and ADHD traits were measured in 56 ASD/31 ADHD SPX families, 59 ASD/171 ADHD MPX families and 203 control families. In ASD but not ADHD, behavioral traits were less elevated in SPX than MPX unaffected relatives, suggesting that SPX–MPX stratification may thus help parse ASD, but not ADHD heterogeneity. Particularly unaffected relatives from MPX ASD/ADHD families displayed elevated trait levels of both disorders, indicating shared (multifactorial) underpinnings underlying ASD and ADHD in these families. Cross-disorder traits were highest in MPX ASD unaffected siblings. En ligne : http://dx.doi.org/10.1007/s10803-014-2220-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Simplex and Multiplex Stratification in ASD and ADHD Families: A Promising Approach for Identifying Overlapping and Unique Underpinnings of ASD and ADHD? [Texte imprimé et/ou numérique] / Anoek M. OERLEMANS, Auteur ; Catharina A. HARTMAN, Auteur ; Yvette G. E. DE BRUIJN, Auteur ; Daphne J. VAN STEIJN, Auteur ; Barbara FRANKE, Auteur ; Jan K. BUITELAAR, Auteur ; Nanda N. ROMMELSE, Auteur . - p.645-657. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.645-657 Mots-clés : Autism spectrum disorders (ASD)  Attention-deficit/hyperactivity disorder (ADHD)  Simplex–multiplex stratification  Family  Unaffected relative Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are highly heterogeneous neuropsychiatric disorders, that frequently co-occur. This study examined whether stratification into single-incidence (SPX) and multi-incidence (MPX) is helpful in (a) parsing heterogeneity and (b) detecting overlapping and unique underpinnings of the disorders. ASD and ADHD traits were measured in 56 ASD/31 ADHD SPX families, 59 ASD/171 ADHD MPX families and 203 control families. In ASD but not ADHD, behavioral traits were less elevated in SPX than MPX unaffected relatives, suggesting that SPX–MPX stratification may thus help parse ASD, but not ADHD heterogeneity. Particularly unaffected relatives from MPX ASD/ADHD families displayed elevated trait levels of both disorders, indicating shared (multifactorial) underpinnings underlying ASD and ADHD in these families. Cross-disorder traits were highest in MPX ASD unaffected siblings. En ligne : http://dx.doi.org/10.1007/s10803-014-2220-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

The Relationship Between Auditory Processing and Restricted, Repetitive Behaviors in Adults with Autism Spectrum Disorders / Niko KARGAS in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.658-668 Titre : The Relationship Between Auditory Processing and Restricted, Repetitive Behaviors in Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Niko KARGAS, Auteur ; Beatriz LOPEZ, Auteur ; Vasudevi REDDY, Auteur ; Paul MORRIS, Auteur Article en page(s) : p.658-668 Langues : Anglais (eng) Mots-clés : Autism  Auditory processing  Restricted, repetitive behaviours  Sensory processing Index. décimale : PER Périodiques Résumé : Current views suggest that autism spectrum disorders (ASDs) are characterised by enhanced low-level auditory discrimination abilities. Little is known, however, about whether enhanced abilities are universal in ASD and how they relate to symptomatology. We tested auditory discrimination for intensity, frequency and duration in 21 adults with ASD and 21 IQ and age-matched controls. Contrary to predictions, there were significant deficits in ASD on all acoustic parameters. The findings suggest that low-level auditory discrimination ability varies widely within ASD and this variability relates to IQ level, and influences the severity of restricted and repetitive behaviours (RRBs). We suggest that it is essential to further our understanding of the potential contributing role of sensory perception ability on the emergence of RRBs. En ligne : http://dx.doi.org/10.1007/s10803-014-2219-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] The Relationship Between Auditory Processing and Restricted, Repetitive Behaviors in Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Niko KARGAS, Auteur ; Beatriz LOPEZ, Auteur ; Vasudevi REDDY, Auteur ; Paul MORRIS, Auteur . - p.658-668. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.658-668 Mots-clés : Autism  Auditory processing  Restricted, repetitive behaviours  Sensory processing Index. décimale : PER Périodiques Résumé : Current views suggest that autism spectrum disorders (ASDs) are characterised by enhanced low-level auditory discrimination abilities. Little is known, however, about whether enhanced abilities are universal in ASD and how they relate to symptomatology. We tested auditory discrimination for intensity, frequency and duration in 21 adults with ASD and 21 IQ and age-matched controls. Contrary to predictions, there were significant deficits in ASD on all acoustic parameters. The findings suggest that low-level auditory discrimination ability varies widely within ASD and this variability relates to IQ level, and influences the severity of restricted and repetitive behaviours (RRBs). We suggest that it is essential to further our understanding of the potential contributing role of sensory perception ability on the emergence of RRBs. En ligne : http://dx.doi.org/10.1007/s10803-014-2219-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Reducing the Need for Personal Supports Among Workers with Autism Using an iPod Touch as an Assistive Technology: Delayed Randomized Control Trial / Tony GENTRY in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.669-684 Titre : Reducing the Need for Personal Supports Among Workers with Autism Using an iPod Touch as an Assistive Technology: Delayed Randomized Control Trial Type de document : Texte imprimé et/ou numérique Auteurs : Tony GENTRY, Auteur ; Richard KRINER, Auteur ; Adam SIMA, Auteur ; Jennifer MCDONOUGH, Auteur ; Paul WEHMAN, Auteur Article en page(s) : p.669-684 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorder  Assistive technology  Employment  Occupational therapy  Vocational rehabilitation Index. décimale : PER Périodiques Résumé : Personal digital assistants (PDAs) are versatile task organizers that hold promise as assistive technologies for people with cognitive-behavioral challenges. This delayed randomized controlled trial compared two groups of adult workers with autism spectrum disorder (ASD) to determine whether the use of an Apple iPod Touch PDA as a vocational support improves work performance and reduces personal support needs on the job. Baseline data were collected on 50 adults with ASD who were beginning a vocational placement supported by a job coach. Participants were randomized to receive training in the use of a PDA as a vocational aid upon starting their job or after working 12 weeks without PDA support. Workers who received PDA training at the beginning of their job placement required significantly less hours of job coaching support (p = 0.013) during their first 12 weeks on the job than those who had not yet received the intervention. Functional performance between the two groups was not significantly different. The significant difference in hours of job coaching support persisted during the subsequent 12 weeks, in which both groups used a PDA (p = 0.017). En ligne : http://dx.doi.org/10.1007/s10803-014-2221-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Reducing the Need for Personal Supports Among Workers with Autism Using an iPod Touch as an Assistive Technology: Delayed Randomized Control Trial [Texte imprimé et/ou numérique] / Tony GENTRY, Auteur ; Richard KRINER, Auteur ; Adam SIMA, Auteur ; Jennifer MCDONOUGH, Auteur ; Paul WEHMAN, Auteur . - p.669-684. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.669-684 Mots-clés : Autism  Autism spectrum disorder  Assistive technology  Employment  Occupational therapy  Vocational rehabilitation Index. décimale : PER Périodiques Résumé : Personal digital assistants (PDAs) are versatile task organizers that hold promise as assistive technologies for people with cognitive-behavioral challenges. This delayed randomized controlled trial compared two groups of adult workers with autism spectrum disorder (ASD) to determine whether the use of an Apple iPod Touch PDA as a vocational support improves work performance and reduces personal support needs on the job. Baseline data were collected on 50 adults with ASD who were beginning a vocational placement supported by a job coach. Participants were randomized to receive training in the use of a PDA as a vocational aid upon starting their job or after working 12 weeks without PDA support. Workers who received PDA training at the beginning of their job placement required significantly less hours of job coaching support (p = 0.013) during their first 12 weeks on the job than those who had not yet received the intervention. Functional performance between the two groups was not significantly different. The significant difference in hours of job coaching support persisted during the subsequent 12 weeks, in which both groups used a PDA (p = 0.017). En ligne : http://dx.doi.org/10.1007/s10803-014-2221-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Sibling Involvement in Interventions for Individuals with Autism Spectrum Disorders: A Systematic Review / Carolyn M. SHIVERS in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.685-696 Titre : Sibling Involvement in Interventions for Individuals with Autism Spectrum Disorders: A Systematic Review Type de document : Texte imprimé et/ou numérique Auteurs : Carolyn M. SHIVERS, Auteur ; Joshua B. PLAVNICK, Auteur Article en page(s) : p.685-696 Langues : Anglais (eng) Mots-clés : Siblings  Autism spectrum disorder  Intervention  Review Index. décimale : PER Périodiques Résumé : Many researchers have studied various interventions for individuals with autism spectrum disorder (ASD). Occasionally, siblings will be included in intervention studies, participating in programs designed to address a number of challenges faced by individuals with ASD. Although sibling involvement in such interventions is not a new phenomenon, there is no consistent method for including siblings in treatment for individuals with ASD. The purpose of this article is to review the existing literature describing sibling involvement in interventions among families of children with ASD, describing patterns of research and targeted outcomes. The authors also identify gaps and areas for future consideration from researchers, clinicians, and families. En ligne : http://dx.doi.org/10.1007/s10803-014-2222-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Sibling Involvement in Interventions for Individuals with Autism Spectrum Disorders: A Systematic Review [Texte imprimé et/ou numérique] / Carolyn M. SHIVERS, Auteur ; Joshua B. PLAVNICK, Auteur . - p.685-696. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.685-696 Mots-clés : Siblings  Autism spectrum disorder  Intervention  Review Index. décimale : PER Périodiques Résumé : Many researchers have studied various interventions for individuals with autism spectrum disorder (ASD). Occasionally, siblings will be included in intervention studies, participating in programs designed to address a number of challenges faced by individuals with ASD. Although sibling involvement in such interventions is not a new phenomenon, there is no consistent method for including siblings in treatment for individuals with ASD. The purpose of this article is to review the existing literature describing sibling involvement in interventions among families of children with ASD, describing patterns of research and targeted outcomes. The authors also identify gaps and areas for future consideration from researchers, clinicians, and families. En ligne : http://dx.doi.org/10.1007/s10803-014-2222-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Examination of Sex Differences in a Large Sample of Young Children with Autism Spectrum Disorder and Typical Development / Vanessa P. REINHARDT in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.697-706 Titre : Examination of Sex Differences in a Large Sample of Young Children with Autism Spectrum Disorder and Typical Development Type de document : Texte imprimé et/ou numérique Auteurs : Vanessa P. REINHARDT, Auteur ; Amy M. WETHERBY, Auteur ; Christopher SCHATSCHNEIDER, Auteur ; Catherine LORD, Auteur Article en page(s) : p.697-706 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sex differences  Social communication  Adaptive behavior  Developmental functioning Index. décimale : PER Périodiques Résumé : Despite consistent and substantive research documenting a large male to female ratio in Autism Spectrum Disorder (ASD), only a modest body of research exists examining sex differences in characteristics. This study examined sex differences in developmental functioning and early social communication in children with ASD as compared to children with typical development. Sex differences in adaptive behavior and autism symptoms were also examined in children with ASD. Participants (n = 511) were recruited from the Florida State University FIRST WORDS® Project and University of Michigan Autism and Communication Disorders Center. Analyses did not reveal significant effects of sex or a diagnostic group by sex interaction, suggesting a similar phenotype in males and females early in development. Further research is needed to examine sex differences across development. En ligne : http://dx.doi.org/10.1007/s10803-014-2223-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Examination of Sex Differences in a Large Sample of Young Children with Autism Spectrum Disorder and Typical Development [Texte imprimé et/ou numérique] / Vanessa P. REINHARDT, Auteur ; Amy M. WETHERBY, Auteur ; Christopher SCHATSCHNEIDER, Auteur ; Catherine LORD, Auteur . - p.697-706. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.697-706 Mots-clés : Autism spectrum disorder  Sex differences  Social communication  Adaptive behavior  Developmental functioning Index. décimale : PER Périodiques Résumé : Despite consistent and substantive research documenting a large male to female ratio in Autism Spectrum Disorder (ASD), only a modest body of research exists examining sex differences in characteristics. This study examined sex differences in developmental functioning and early social communication in children with ASD as compared to children with typical development. Sex differences in adaptive behavior and autism symptoms were also examined in children with ASD. Participants (n = 511) were recruited from the Florida State University FIRST WORDS® Project and University of Michigan Autism and Communication Disorders Center. Analyses did not reveal significant effects of sex or a diagnostic group by sex interaction, suggesting a similar phenotype in males and females early in development. Further research is needed to examine sex differences across development. En ligne : http://dx.doi.org/10.1007/s10803-014-2223-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Outcomes in Adult Life Among Siblings of Individuals with Autism / Patricia HOWLIN in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.707-718 Titre : Outcomes in Adult Life Among Siblings of Individuals with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Patricia HOWLIN, Auteur ; Philippa MOSS, Auteur ; Sarah SAVAGE, Auteur ; Patrick BOLTON, Auteur ; Michael RUTTER, Auteur Article en page(s) : p.707-718 Langues : Anglais (eng) Mots-clés : Autism  Siblings  Adults  Outcomes Index. décimale : PER Périodiques Résumé : Little is known about adult siblings of individuals with autism. We report on cognitive, social and mental health outcomes in 87 adult siblings (mean age 39 years). When younger all had been assessed either as being “unaffected” by autism (n = 69) or as meeting criteria for the “Broader Autism Phenotype” (BAP, n = 18). As adults, all scored within the average range on tests of intelligence, numeracy and literacy. “Unaffected” siblings were functioning well in terms of jobs, independence and social relationships. Levels of social relationships and employment were significantly lower in the BAP group; autism traits and mental health problems were significantly higher. The data suggest that the “broader autism phenotype” is a meaningful concept but more sensitive diagnostic measures are required. En ligne : http://dx.doi.org/10.1007/s10803-014-2224-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Outcomes in Adult Life Among Siblings of Individuals with Autism [Texte imprimé et/ou numérique] / Patricia HOWLIN, Auteur ; Philippa MOSS, Auteur ; Sarah SAVAGE, Auteur ; Patrick BOLTON, Auteur ; Michael RUTTER, Auteur . - p.707-718. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.707-718 Mots-clés : Autism  Siblings  Adults  Outcomes Index. décimale : PER Périodiques Résumé : Little is known about adult siblings of individuals with autism. We report on cognitive, social and mental health outcomes in 87 adult siblings (mean age 39 years). When younger all had been assessed either as being “unaffected” by autism (n = 69) or as meeting criteria for the “Broader Autism Phenotype” (BAP, n = 18). As adults, all scored within the average range on tests of intelligence, numeracy and literacy. “Unaffected” siblings were functioning well in terms of jobs, independence and social relationships. Levels of social relationships and employment were significantly lower in the BAP group; autism traits and mental health problems were significantly higher. The data suggest that the “broader autism phenotype” is a meaningful concept but more sensitive diagnostic measures are required. En ligne : http://dx.doi.org/10.1007/s10803-014-2224-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders / Vincent M. YAU in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730 Titre : Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur Article en page(s) : p.719-730 Langues : Anglais (eng) Mots-clés : Thyroid  Thyroid stimulating hormone  Autism  Pregnancy  Developmental delay Index. décimale : PER Périodiques Résumé : Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). En ligne : http://dx.doi.org/10.1007/s10803-014-2227-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Vincent M. YAU, Auteur ; Marta LUTSKY, Auteur ; Cathleen K. YOSHIDA, Auteur ; Bill LASLEY, Auteur ; Martin KHARRAZI, Auteur ; Gayle WINDHAM, Auteur ; Nancy GEE, Auteur ; Lisa A. CROEN, Auteur . - p.719-730. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.719-730 Mots-clés : Thyroid  Thyroid stimulating hormone  Autism  Pregnancy  Developmental delay Index. décimale : PER Périodiques Résumé : Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000–2001were identified: ASD (n = 78), developmental delay (n = 45), and general population controls (GP) (n = 149). Samples were retrieved from prenatal and newborn screening specimen archives. Adjusted logistic regression models showed inverse associations between ASD and log transformed TSH levels in maternal serum samples (ASD vs. GP: OR [95 % CI] 0.33 [0.12–0.91], Early Onset ASD vs. GP: 0.31 [0.10–0.98]). Results for thyroid levels in newborn blood samples were similar though not significant (ASD vs. GP: 0.61 [0.18–2.04]). En ligne : http://dx.doi.org/10.1007/s10803-014-2227-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Sexuality in Adolescent Boys with Autism Spectrum Disorder: Self-reported Behaviours and Attitudes / Jeroen DEWINTER in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.731-741 Titre : Sexuality in Adolescent Boys with Autism Spectrum Disorder: Self-reported Behaviours and Attitudes Type de document : Texte imprimé et/ou numérique Auteurs : Jeroen DEWINTER, Auteur ; Robert R. J. M. VERMEIREN, Auteur ; Ine VANWESENBEECK, Auteur ; Jill LOBBESTAEL, Auteur ; Chijs VAN NIEUWENHUIZEN, Auteur Article en page(s) : p.731-741 Langues : Anglais (eng) Mots-clés : Autism  Asperger’s disorder  Sexuality  Sexual behaviour Index. décimale : PER Périodiques Résumé : Differences in sexual functioning of adolescents with and without autism spectrum disorder (ASD) are understudied. In the current study, self-reported sexual behaviours, interests and attitudes of 50 adolescent boys, aged 15–18, with at least average intelligence and diagnosed with ASD, were compared with a matched general population control group of 90 boys. Results demonstrated substantial similarity between the groups in terms of sexual behaviours. The only significant difference was that boys with ASD reacted more tolerant towards homosexuality compared to the control group. Results reveal that sexuality is a normative part of adolescent development in high-functioning boys with ASD. Hence, attention should be given to this topic in education and mental health care. En ligne : http://dx.doi.org/10.1007/s10803-014-2226-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Sexuality in Adolescent Boys with Autism Spectrum Disorder: Self-reported Behaviours and Attitudes [Texte imprimé et/ou numérique] / Jeroen DEWINTER, Auteur ; Robert R. J. M. VERMEIREN, Auteur ; Ine VANWESENBEECK, Auteur ; Jill LOBBESTAEL, Auteur ; Chijs VAN NIEUWENHUIZEN, Auteur . - p.731-741. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.731-741 Mots-clés : Autism  Asperger’s disorder  Sexuality  Sexual behaviour Index. décimale : PER Périodiques Résumé : Differences in sexual functioning of adolescents with and without autism spectrum disorder (ASD) are understudied. In the current study, self-reported sexual behaviours, interests and attitudes of 50 adolescent boys, aged 15–18, with at least average intelligence and diagnosed with ASD, were compared with a matched general population control group of 90 boys. Results demonstrated substantial similarity between the groups in terms of sexual behaviours. The only significant difference was that boys with ASD reacted more tolerant towards homosexuality compared to the control group. Results reveal that sexuality is a normative part of adolescent development in high-functioning boys with ASD. Hence, attention should be given to this topic in education and mental health care. En ligne : http://dx.doi.org/10.1007/s10803-014-2226-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Evidence for Specificity of Motor Impairments in Catching and Balance in Children with Autism / Katarina AMENT in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.742-751 Titre : Evidence for Specificity of Motor Impairments in Catching and Balance in Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Katarina AMENT, Auteur ; Amanda MEJIA, Auteur ; Rebecca BUHLMAN, Auteur ; Shannon ERKLIN, Auteur ; Brian S. CAFFO, Auteur ; Stewart MOSTOFSKY, Auteur ; Ericka WODKA, Auteur Article en page(s) : p.742-751 Langues : Anglais (eng) Mots-clés : Autism  Attention-deficit/hyperactivity disorder  Motor impairment  Specificity Index. décimale : PER Périodiques Résumé : To evaluate evidence for motor impairment specificity in autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). Children completed performance-based assessment of motor functioning (Movement Assessment Battery for Children: MABC-2). Logistic regression models were used to predict group membership. In the models comparing typically developing and developmental disability (DD), all three MABC subscale scores were significantly negatively associated with having a DD. In the models comparing ADHD and ASD, catching and static balance items were associated with ASD group membership, with a 1 point decrease in performance increasing odds of ASD by 36 and 39 %, respectively. Impairments in motor skills requiring the coupling of visual and temporal feedback to guide and adjust movement appear specifically deficient in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2229-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Evidence for Specificity of Motor Impairments in Catching and Balance in Children with Autism [Texte imprimé et/ou numérique] / Katarina AMENT, Auteur ; Amanda MEJIA, Auteur ; Rebecca BUHLMAN, Auteur ; Shannon ERKLIN, Auteur ; Brian S. CAFFO, Auteur ; Stewart MOSTOFSKY, Auteur ; Ericka WODKA, Auteur . - p.742-751. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.742-751 Mots-clés : Autism  Attention-deficit/hyperactivity disorder  Motor impairment  Specificity Index. décimale : PER Périodiques Résumé : To evaluate evidence for motor impairment specificity in autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). Children completed performance-based assessment of motor functioning (Movement Assessment Battery for Children: MABC-2). Logistic regression models were used to predict group membership. In the models comparing typically developing and developmental disability (DD), all three MABC subscale scores were significantly negatively associated with having a DD. In the models comparing ADHD and ASD, catching and static balance items were associated with ASD group membership, with a 1 point decrease in performance increasing odds of ASD by 36 and 39 %, respectively. Impairments in motor skills requiring the coupling of visual and temporal feedback to guide and adjust movement appear specifically deficient in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2229-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Parent and Family Outcomes of PEERS: A Social Skills Intervention for Adolescents with Autism Spectrum Disorder / Jeffrey S. KARST in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.752-765 Titre : Parent and Family Outcomes of PEERS: A Social Skills Intervention for Adolescents with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Jeffrey S. KARST, Auteur ; Amy Vaughan VAN HECKE, Auteur ; Audrey M. CARSON, Auteur ; Sheryl STEVENS, Auteur ; Kirsten SCHOHL, Auteur ; Bridget DOLAN, Auteur Article en page(s) : p.752-765 Langues : Anglais (eng) Mots-clés : Autism  Parents  Caregivers  PEERS  Intervention Index. décimale : PER Périodiques Résumé : Raising a child with an Autism Spectrum Disorder (ASD) is associated with increased family chaos and parent distress. Successful long-term treatment outcomes are dependent on healthy systemic functioning, but the family impact of treatment is rarely evaluated. The Program for the Education and Enrichment of Relational Skills (PEERS) is a social skills intervention designed for adolescents with high-functioning ASD. This study assessed the impact of PEERS on family chaos, parenting stress, and parenting self-efficacy via a randomized, controlled trial. Results suggested beneficial effects for the experimental group in the domain of family chaos compared to the waitlist control, while parents in the PEERS experimental group also demonstrated increased parenting self-efficacy. These findings highlight adjunctive family system benefits of PEERS intervention and suggest the need for overall better understanding of parent and family outcomes of ASD interventions. En ligne : http://dx.doi.org/10.1007/s10803-014-2231-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Parent and Family Outcomes of PEERS: A Social Skills Intervention for Adolescents with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Jeffrey S. KARST, Auteur ; Amy Vaughan VAN HECKE, Auteur ; Audrey M. CARSON, Auteur ; Sheryl STEVENS, Auteur ; Kirsten SCHOHL, Auteur ; Bridget DOLAN, Auteur . - p.752-765. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.752-765 Mots-clés : Autism  Parents  Caregivers  PEERS  Intervention Index. décimale : PER Périodiques Résumé : Raising a child with an Autism Spectrum Disorder (ASD) is associated with increased family chaos and parent distress. Successful long-term treatment outcomes are dependent on healthy systemic functioning, but the family impact of treatment is rarely evaluated. The Program for the Education and Enrichment of Relational Skills (PEERS) is a social skills intervention designed for adolescents with high-functioning ASD. This study assessed the impact of PEERS on family chaos, parenting stress, and parenting self-efficacy via a randomized, controlled trial. Results suggested beneficial effects for the experimental group in the domain of family chaos compared to the waitlist control, while parents in the PEERS experimental group also demonstrated increased parenting self-efficacy. These findings highlight adjunctive family system benefits of PEERS intervention and suggest the need for overall better understanding of parent and family outcomes of ASD interventions. En ligne : http://dx.doi.org/10.1007/s10803-014-2231-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Does Gender Influence Core Deficits in ASD? An Investigation into Social-Communication and Play of Girls and Boys with ASD / Clare HARROP in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.766-777 Titre : Does Gender Influence Core Deficits in ASD? An Investigation into Social-Communication and Play of Girls and Boys with ASD Type de document : Texte imprimé et/ou numérique Auteurs : Clare HARROP, Auteur ; Stephanie Y. SHIRE, Auteur ; Amanda GULSRUD, Auteur ; Ya-Chih CHANG, Auteur ; Eric ISHIJIMA, Auteur ; Kathy LAWTON, Auteur ; Connie KASARI, Auteur Article en page(s) : p.766-777 Langues : Anglais (eng) Mots-clés : Autism  Gender  Social-communication  Joint attention  Play Index. décimale : PER Périodiques Résumé : Due to the predominance of boys diagnosed with autism spectrum disorders (ASD), girls are rarely studied independently. Research specifically focusing on play and social-communication in girls with ASD is extremely varied. We were interested in whether girls with ASD demonstrated equivalent social-communication and play skills in early childhood relative to boys, using two measures focused on the specific quantification of these variables. We also examined whether the associations between developmental variables and social-communication and play differed by gender. Forty girls with ASD were individually matched to 40 boys based on ASD severity. Our results suggest that girls and boys were more similar than different, however they also raise questions about the potential differential associations between development and requesting ability in girls and boys with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Does Gender Influence Core Deficits in ASD? An Investigation into Social-Communication and Play of Girls and Boys with ASD [Texte imprimé et/ou numérique] / Clare HARROP, Auteur ; Stephanie Y. SHIRE, Auteur ; Amanda GULSRUD, Auteur ; Ya-Chih CHANG, Auteur ; Eric ISHIJIMA, Auteur ; Kathy LAWTON, Auteur ; Connie KASARI, Auteur . - p.766-777. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.766-777 Mots-clés : Autism  Gender  Social-communication  Joint attention  Play Index. décimale : PER Périodiques Résumé : Due to the predominance of boys diagnosed with autism spectrum disorders (ASD), girls are rarely studied independently. Research specifically focusing on play and social-communication in girls with ASD is extremely varied. We were interested in whether girls with ASD demonstrated equivalent social-communication and play skills in early childhood relative to boys, using two measures focused on the specific quantification of these variables. We also examined whether the associations between developmental variables and social-communication and play differed by gender. Forty girls with ASD were individually matched to 40 boys based on ASD severity. Our results suggest that girls and boys were more similar than different, however they also raise questions about the potential differential associations between development and requesting ability in girls and boys with ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Feasibility and Effectiveness of Very Early Intervention for Infants At-Risk for Autism Spectrum Disorder: A Systematic Review / Jessica BRADSHAW in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.778-794 Titre : Feasibility and Effectiveness of Very Early Intervention for Infants At-Risk for Autism Spectrum Disorder: A Systematic Review Type de document : Texte imprimé et/ou numérique Auteurs : Jessica BRADSHAW, Auteur ; Amanda Mossman STEINER, Auteur ; Grace GENGOUX, Auteur ; Lynn Kern KOEGEL, Auteur Article en page(s) : p.778-794 Langues : Anglais (eng) Mots-clés : Autism  Early intervention  Infancy  High-risk infants  Treatment Index. décimale : PER Périodiques Résumé : Early detection methods for autism spectrum disorder (ASD) in infancy are rapidly advancing, yet the development of interventions for infants under two years with or at-risk for ASD remains limited. In order to guide research and practice, this paper systematically reviewed studies investigating interventions for infants under 24 months with or at-risk for ASD. Nine studies were identified and evaluated for: (a) participants, (b) intervention approach (c) experimental design, and (d) outcomes. Studies that collected parent measures reported positive findings for parent acceptability, satisfaction, and improvement in parent implementation of treatment. Infant gains in social-communicative and developmental skills were observed following intervention in most of the reviewed studies, while comparisons with treatment-as-usual control groups elucidate the need for further research. These studies highlight the feasibility of very early intervention and provide preliminary evidence that intervention for at-risk infants may be beneficial for infants and parents. En ligne : http://dx.doi.org/10.1007/s10803-014-2235-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Feasibility and Effectiveness of Very Early Intervention for Infants At-Risk for Autism Spectrum Disorder: A Systematic Review [Texte imprimé et/ou numérique] / Jessica BRADSHAW, Auteur ; Amanda Mossman STEINER, Auteur ; Grace GENGOUX, Auteur ; Lynn Kern KOEGEL, Auteur . - p.778-794. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.778-794 Mots-clés : Autism  Early intervention  Infancy  High-risk infants  Treatment Index. décimale : PER Périodiques Résumé : Early detection methods for autism spectrum disorder (ASD) in infancy are rapidly advancing, yet the development of interventions for infants under two years with or at-risk for ASD remains limited. In order to guide research and practice, this paper systematically reviewed studies investigating interventions for infants under 24 months with or at-risk for ASD. Nine studies were identified and evaluated for: (a) participants, (b) intervention approach (c) experimental design, and (d) outcomes. Studies that collected parent measures reported positive findings for parent acceptability, satisfaction, and improvement in parent implementation of treatment. Infant gains in social-communicative and developmental skills were observed following intervention in most of the reviewed studies, while comparisons with treatment-as-usual control groups elucidate the need for further research. These studies highlight the feasibility of very early intervention and provide preliminary evidence that intervention for at-risk infants may be beneficial for infants and parents. En ligne : http://dx.doi.org/10.1007/s10803-014-2235-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume / J. Christopher EDGAR in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804 Titre : Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume Type de document : Texte imprimé et/ou numérique Auteurs : J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur Article en page(s) : p.795-804 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Alpha  Resting-state  Magnetoencephalography  Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume [Texte imprimé et/ou numérique] / J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur . - p.795-804. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804 Mots-clés : Autism spectrum disorder  Alpha  Resting-state  Magnetoencephalography  Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder / Haylie L. MILLER in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.805-815 Titre : Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Haylie L. MILLER, Auteur ; Michael E. RAGOZZINO, Auteur ; Edwin H. Jr COOK, Auteur ; John A. SWEENEY, Auteur ; Matthew W. MOSCONI, Auteur Article en page(s) : p.805-815 Langues : Anglais (eng) Mots-clés : Cognitive flexibility  Insistence on sameness  Repetitive behavior Index. décimale : PER Périodiques Résumé : The neurocognitive impairments associated with restricted and repetitive behaviors (RRBs) in autism spectrum disorder (ASD) are not yet clear. Prior studies indicate that individuals with ASD show reduced cognitive flexibility, which could reflect difficulty shifting from a previously learned response pattern or a failure to maintain a new response set. We examined different error types on a test of set-shifting completed by 60 individuals with ASD and 55 age- and nonverbal IQ-matched controls. Individuals with ASD were able to initially shift sets, but they exhibited difficulty maintaining new response sets. Difficulty with set maintenance was related to increased severity of RRBs. General difficulty maintaining new response sets and a heightened tendency to revert to old preferences may contribute to RRBs. En ligne : http://dx.doi.org/10.1007/s10803-014-2244-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Cognitive Set Shifting Deficits and Their Relationship to Repetitive Behaviors in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Haylie L. MILLER, Auteur ; Michael E. RAGOZZINO, Auteur ; Edwin H. Jr COOK, Auteur ; John A. SWEENEY, Auteur ; Matthew W. MOSCONI, Auteur . - p.805-815. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.805-815 Mots-clés : Cognitive flexibility  Insistence on sameness  Repetitive behavior Index. décimale : PER Périodiques Résumé : The neurocognitive impairments associated with restricted and repetitive behaviors (RRBs) in autism spectrum disorder (ASD) are not yet clear. Prior studies indicate that individuals with ASD show reduced cognitive flexibility, which could reflect difficulty shifting from a previously learned response pattern or a failure to maintain a new response set. We examined different error types on a test of set-shifting completed by 60 individuals with ASD and 55 age- and nonverbal IQ-matched controls. Individuals with ASD were able to initially shift sets, but they exhibited difficulty maintaining new response sets. Difficulty with set maintenance was related to increased severity of RRBs. General difficulty maintaining new response sets and a heightened tendency to revert to old preferences may contribute to RRBs. En ligne : http://dx.doi.org/10.1007/s10803-014-2244-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

DSM-5 Changes and the Prevalence of Parent-Reported Autism Spectrum Symptoms in Fragile X Syndrome / Anne C. WHEELER in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.816-829 Titre : DSM-5 Changes and the Prevalence of Parent-Reported Autism Spectrum Symptoms in Fragile X Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Anne C. WHEELER, Auteur ; Joanna MUSSEY, Auteur ; Adrienne VILLAGOMEZ, Auteur ; Ellen BISHOP, Auteur ; Melissa RASPA, Auteur ; Anne EDWARDS, Auteur ; James W. BODFISH, Auteur ; Carla M. BANN, Auteur ; Donald B. Jr BAILEY, Auteur Article en page(s) : p.816-829 Langues : Anglais (eng) Mots-clés : Fragile X syndrome  DSM-5 criteria  Autism spectrum disorder diagnoses Index. décimale : PER Périodiques Résumé : We used survey methodology to assess parent-reported autism symptomology in 758 individuals (639 males; 119 females) with fragile X syndrome (FXS). Caregivers reported whether their child with FXS had been diagnosed with an autism spectrum disorder (ASD) and endorsed symptoms based on a list of observable behaviors related to ASD diagnoses. Symptom counts were categorized based on DSM-IV-TR and DSM-5 criteria. Based on behavioral symptoms endorsed by caregivers, 38.7 % of males and 24.7 % of females met criteria for DSM-IV-TR diagnosis of autistic disorder. Significantly fewer males (27.8 %) and females (11.3 %) met criteria for ASD based on DSM-5 criteria. Although 86.4 % of males and 61.7 % of females met criteria for the restricted and repetitive behavior domain for DSM-5, only 29.4 % of males and 13.0 % of females met criteria for the social communication and interaction (SCI) domain. Relaxing the social communication criteria by one symptom count led to a threefold increase in those meeting criteria for ASD, suggesting the importance of subthreshold SCI symptoms for individuals with FXS in ASD diagnoses. Findings suggest important differences in the way ASD may be conceptualized in FXS based on the new DSM-5 criteria. En ligne : http://dx.doi.org/10.1007/s10803-014-2246-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] DSM-5 Changes and the Prevalence of Parent-Reported Autism Spectrum Symptoms in Fragile X Syndrome [Texte imprimé et/ou numérique] / Anne C. WHEELER, Auteur ; Joanna MUSSEY, Auteur ; Adrienne VILLAGOMEZ, Auteur ; Ellen BISHOP, Auteur ; Melissa RASPA, Auteur ; Anne EDWARDS, Auteur ; James W. BODFISH, Auteur ; Carla M. BANN, Auteur ; Donald B. Jr BAILEY, Auteur . - p.816-829. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.816-829 Mots-clés : Fragile X syndrome  DSM-5 criteria  Autism spectrum disorder diagnoses Index. décimale : PER Périodiques Résumé : We used survey methodology to assess parent-reported autism symptomology in 758 individuals (639 males; 119 females) with fragile X syndrome (FXS). Caregivers reported whether their child with FXS had been diagnosed with an autism spectrum disorder (ASD) and endorsed symptoms based on a list of observable behaviors related to ASD diagnoses. Symptom counts were categorized based on DSM-IV-TR and DSM-5 criteria. Based on behavioral symptoms endorsed by caregivers, 38.7 % of males and 24.7 % of females met criteria for DSM-IV-TR diagnosis of autistic disorder. Significantly fewer males (27.8 %) and females (11.3 %) met criteria for ASD based on DSM-5 criteria. Although 86.4 % of males and 61.7 % of females met criteria for the restricted and repetitive behavior domain for DSM-5, only 29.4 % of males and 13.0 % of females met criteria for the social communication and interaction (SCI) domain. Relaxing the social communication criteria by one symptom count led to a threefold increase in those meeting criteria for ASD, suggesting the importance of subthreshold SCI symptoms for individuals with FXS in ASD diagnoses. Findings suggest important differences in the way ASD may be conceptualized in FXS based on the new DSM-5 criteria. En ligne : http://dx.doi.org/10.1007/s10803-014-2246-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Integrated Play Groups: Promoting Symbolic Play and Social Engagement with Typical Peers in Children with ASD Across Settings / Pamela WOLFBERG in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.830-845 Titre : Integrated Play Groups: Promoting Symbolic Play and Social Engagement with Typical Peers in Children with ASD Across Settings Type de document : Texte imprimé et/ou numérique Auteurs : Pamela WOLFBERG, Auteur ; Mila N. DEWITT, Auteur ; Gregory S. YOUNG, Auteur ; Thanh NGUYEN, Auteur Article en page(s) : p.830-845 Langues : Anglais (eng) Mots-clés : Play  Social  Symbolic  Peers  Inclusion  Sociocultural Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) face pervasive challenges in symbolic and social play development. The Integrated Play Groups (IPG) model provides intensive guidance for children with ASD to participate with typical peers in mutually engaging experiences in natural settings. This study examined the effects of a 12-week IPG intervention on the symbolic and social play of 48 children with ASD using a repeated measures design. The findings revealed significant gains in symbolic and social play that generalized to unsupported play with unfamiliar peers. Consistent with prior studies, the outcomes provide robust and compelling evidence that further validate the efficacy of the IPG model. Theoretical and practical implications for maximizing children’s developmental potential and social inclusion in play are discussed. En ligne : http://dx.doi.org/10.1007/s10803-014-2245-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Integrated Play Groups: Promoting Symbolic Play and Social Engagement with Typical Peers in Children with ASD Across Settings [Texte imprimé et/ou numérique] / Pamela WOLFBERG, Auteur ; Mila N. DEWITT, Auteur ; Gregory S. YOUNG, Auteur ; Thanh NGUYEN, Auteur . - p.830-845. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.830-845 Mots-clés : Play  Social  Symbolic  Peers  Inclusion  Sociocultural Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) face pervasive challenges in symbolic and social play development. The Integrated Play Groups (IPG) model provides intensive guidance for children with ASD to participate with typical peers in mutually engaging experiences in natural settings. This study examined the effects of a 12-week IPG intervention on the symbolic and social play of 48 children with ASD using a repeated measures design. The findings revealed significant gains in symbolic and social play that generalized to unsupported play with unfamiliar peers. Consistent with prior studies, the outcomes provide robust and compelling evidence that further validate the efficacy of the IPG model. Theoretical and practical implications for maximizing children’s developmental potential and social inclusion in play are discussed. En ligne : http://dx.doi.org/10.1007/s10803-014-2245-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Measuring and Supporting Language Function for Children with Autism: Evidence from a Randomized Control Trial of a Social-Interaction-Based Therapy / Devin M. CASENHISER in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.846-857 Titre : Measuring and Supporting Language Function for Children with Autism: Evidence from a Randomized Control Trial of a Social-Interaction-Based Therapy Type de document : Texte imprimé et/ou numérique Auteurs : Devin M. CASENHISER, Auteur ; Amanda V. BINNS, Auteur ; Fay MCGILL, Auteur ; Olga MORDERER, Auteur ; Stuart G. SHANKER, Auteur Article en page(s) : p.846-857 Langues : Anglais (eng) Mots-clés : Autism  Language development  MEHRIT  Speech acts  Communicative acts Index. décimale : PER Périodiques Résumé : In a report of the effectiveness of MEHRIT, a social-interaction-based intervention for autism, Casenhiser et al. (Autism 17(2):220–241, 2013) failed to find a significant advantage for language development in the treatment group using standardized language assessments. We present the results from a re-analysis of their results to illustrate the importance of measuring communicative language acts (formally called “speech acts”). Reanalysis confirmed that children in the MEHRIT group outperformed the community treatment group on measures of MLUm, number of utterances produced, and various speech act categories. The study underscores the importance of functional language measures in guiding and evaluating treatment for children with autism, and suggests that MEHRIT is effective in improving children’s use of language during parent–child interactions. En ligne : http://dx.doi.org/10.1007/s10803-014-2242-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Measuring and Supporting Language Function for Children with Autism: Evidence from a Randomized Control Trial of a Social-Interaction-Based Therapy [Texte imprimé et/ou numérique] / Devin M. CASENHISER, Auteur ; Amanda V. BINNS, Auteur ; Fay MCGILL, Auteur ; Olga MORDERER, Auteur ; Stuart G. SHANKER, Auteur . - p.846-857. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.846-857 Mots-clés : Autism  Language development  MEHRIT  Speech acts  Communicative acts Index. décimale : PER Périodiques Résumé : In a report of the effectiveness of MEHRIT, a social-interaction-based intervention for autism, Casenhiser et al. (Autism 17(2):220–241, 2013) failed to find a significant advantage for language development in the treatment group using standardized language assessments. We present the results from a re-analysis of their results to illustrate the importance of measuring communicative language acts (formally called “speech acts”). Reanalysis confirmed that children in the MEHRIT group outperformed the community treatment group on measures of MLUm, number of utterances produced, and various speech act categories. The study underscores the importance of functional language measures in guiding and evaluating treatment for children with autism, and suggests that MEHRIT is effective in improving children’s use of language during parent–child interactions. En ligne : http://dx.doi.org/10.1007/s10803-014-2242-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

The Relationship Between Autistic Traits and Social Anxiety, Worry, Obsessive–Compulsive, and Depressive Symptoms: Specific and Non-specific Mediators in a Student Sample / Shi Min LIEW in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.858-872 Titre : The Relationship Between Autistic Traits and Social Anxiety, Worry, Obsessive–Compulsive, and Depressive Symptoms: Specific and Non-specific Mediators in a Student Sample Type de document : Texte imprimé et/ou numérique Auteurs : Shi Min LIEW, Auteur ; Nishta THEVARAJA, Auteur ; Ryan Y. HONG, Auteur ; Iliana MAGIATI, Auteur Article en page(s) : p.858-872 Langues : Anglais (eng) Mots-clés : Autism  Autistic traits  Anxiety  Depression  Mediator  Relationship  Predictor Index. décimale : PER Périodiques Résumé : The high prevalence of anxiety symptoms in individuals with autism spectrum disorders has now been well documented. There is also a positive relationship between autistic traits and anxiety symptoms in unselected samples and individuals with anxiety disorders have more autistic traits compared to those without. Less is known, however, regarding which elements of autistic traits (i.e., social versus non-social/behavioral) or which other variables may mediate this relationship. This study investigated the shared and specific role of five autistic-trait related mediators (social problem-solving, social competence, teasing experiences, prevention from/punishment for preferred repetitive behaviors and aversive sensory experiences) in a non-clinical sample of 252 university students. Autistic traits positively correlated with both anxiety and depressive symptoms. Social competence mediated the relationship between autistic traits and social anxiety symptoms only, while only prevention from preferred repetitive behaviors and frequent aversive sensory experiences mediated the relationship between autistic traits, worry and obsessive–compulsive symptoms. Replication of these findings is required in longitudinal studies and with clinical samples. Limitations of the study are discussed and possible implications for intervention are tentatively suggested. En ligne : http://dx.doi.org/10.1007/s10803-014-2238-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] The Relationship Between Autistic Traits and Social Anxiety, Worry, Obsessive–Compulsive, and Depressive Symptoms: Specific and Non-specific Mediators in a Student Sample [Texte imprimé et/ou numérique] / Shi Min LIEW, Auteur ; Nishta THEVARAJA, Auteur ; Ryan Y. HONG, Auteur ; Iliana MAGIATI, Auteur . - p.858-872. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.858-872 Mots-clés : Autism  Autistic traits  Anxiety  Depression  Mediator  Relationship  Predictor Index. décimale : PER Périodiques Résumé : The high prevalence of anxiety symptoms in individuals with autism spectrum disorders has now been well documented. There is also a positive relationship between autistic traits and anxiety symptoms in unselected samples and individuals with anxiety disorders have more autistic traits compared to those without. Less is known, however, regarding which elements of autistic traits (i.e., social versus non-social/behavioral) or which other variables may mediate this relationship. This study investigated the shared and specific role of five autistic-trait related mediators (social problem-solving, social competence, teasing experiences, prevention from/punishment for preferred repetitive behaviors and aversive sensory experiences) in a non-clinical sample of 252 university students. Autistic traits positively correlated with both anxiety and depressive symptoms. Social competence mediated the relationship between autistic traits and social anxiety symptoms only, while only prevention from preferred repetitive behaviors and frequent aversive sensory experiences mediated the relationship between autistic traits, worry and obsessive–compulsive symptoms. Replication of these findings is required in longitudinal studies and with clinical samples. Limitations of the study are discussed and possible implications for intervention are tentatively suggested. En ligne : http://dx.doi.org/10.1007/s10803-014-2238-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site / Amanda V. BAKIAN in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.873-880 Titre : Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site Type de document : Texte imprimé et/ou numérique Auteurs : Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Paul S. CARBONE, Auteur ; Tyler D. HUNT, Auteur ; Brent PETERSEN, Auteur ; Catherine E. RICE, Auteur Article en page(s) : p.873-880 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autism and Developmental Disabilities Monitoring Network  ASD surveillance  ASD prevalence  Validation  DSM-IV-TR Index. décimale : PER Périodiques Résumé : An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network’s (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74–0.90)], and sensitivity [0.99 (95 % CI 0.96–1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts. En ligne : http://dx.doi.org/10.1007/s10803-014-2187-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site [Texte imprimé et/ou numérique] / Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Paul S. CARBONE, Auteur ; Tyler D. HUNT, Auteur ; Brent PETERSEN, Auteur ; Catherine E. RICE, Auteur . - p.873-880. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.873-880 Mots-clés : Autism spectrum disorder  Autism and Developmental Disabilities Monitoring Network  ASD surveillance  ASD prevalence  Validation  DSM-IV-TR Index. décimale : PER Périodiques Résumé : An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network’s (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74–0.90)], and sensitivity [0.99 (95 % CI 0.96–1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts. En ligne : http://dx.doi.org/10.1007/s10803-014-2187-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Brief Report: Bone Fractures in Children and Adults with Autism Spectrum Disorders / Ann M. NEUMEYER in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.881-887 Titre : Brief Report: Bone Fractures in Children and Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Ann M. NEUMEYER, Auteur ; Julia A. O’ROURKE, Auteur ; Alexandra MASSA, Auteur ; Hang LEE, Auteur ; Elizabeth A. LAWSON, Auteur ; Christopher J. MCDOUGLE, Auteur ; Madhusmita MISRA, Auteur Article en page(s) : p.881-887 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Autism  Fractures  Low bone density  Osteoporosis Index. décimale : PER Périodiques Résumé : Peripubertal boys with autism spectrum disorder (ASD) have lower bone mineral density (BMD) than typically developing controls. However, it is not clear whether lower BMD in ASD results in an increased fracture rate. This study examined the rate of fractures in children and adults with and without ASD using a national database of emergency room visits (Nationwide Emergency Department Sample). A higher odds ratio for hip fractures in children and young adults (3–22 years) as well as older adults (23–50 years) with ASD than those without ASD, and a higher odds ratio for forearm and spine fractures in women ages 23–50 with ASD were found. Further studies are necessary to better understand the decreased bone density in ASD and its implications for fracture development. En ligne : http://dx.doi.org/10.1007/s10803-014-2228-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Brief Report: Bone Fractures in Children and Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Ann M. NEUMEYER, Auteur ; Julia A. O’ROURKE, Auteur ; Alexandra MASSA, Auteur ; Hang LEE, Auteur ; Elizabeth A. LAWSON, Auteur ; Christopher J. MCDOUGLE, Auteur ; Madhusmita MISRA, Auteur . - p.881-887. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.881-887 Mots-clés : Autism spectrum disorders  Autism  Fractures  Low bone density  Osteoporosis Index. décimale : PER Périodiques Résumé : Peripubertal boys with autism spectrum disorder (ASD) have lower bone mineral density (BMD) than typically developing controls. However, it is not clear whether lower BMD in ASD results in an increased fracture rate. This study examined the rate of fractures in children and adults with and without ASD using a national database of emergency room visits (Nationwide Emergency Department Sample). A higher odds ratio for hip fractures in children and young adults (3–22 years) as well as older adults (23–50 years) with ASD than those without ASD, and a higher odds ratio for forearm and spine fractures in women ages 23–50 with ASD were found. Further studies are necessary to better understand the decreased bone density in ASD and its implications for fracture development. En ligne : http://dx.doi.org/10.1007/s10803-014-2228-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology / F. CORREIA in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.888-892 Titre : Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology Type de document : Texte imprimé et/ou numérique Auteurs : F. CORREIA, Auteur ; C. CAFE, Auteur ; J. ALMEIDA, Auteur ; S. MOUGA, Auteur ; G. OLIVEIRA, Auteur Article en page(s) : p.888-892 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Fragile X syndrome  FRAXE  FMR2  Intellectual disability  Compulsive behavior problems Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by impaired social interaction and communication, restricted interests and repetitive behaviors. Fragile X E is associated with X-linked non-specific mild intellectual disability (ID) and with behavioral problems. Most of the known genetic causes of ASD are also causes of ID, implying that these two identities share common genetic bases. We present a child with an ASD with a normal range of intelligence quotient, that later evolved to compulsive behavior. FRAXE locus analysis by polymerase chain reaction revealed a complete mutation of the FMR 2 gene. This report stresses the importance of clinicians being aware of the association between a full mutation of FMR2 and ASD associated with compulsive behavior despite normal intellectual level. En ligne : http://dx.doi.org/10.1007/s10803-014-2185-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Autism Spectrum Disorder: FRAXE Mutation, a Rare Etiology [Texte imprimé et/ou numérique] / F. CORREIA, Auteur ; C. CAFE, Auteur ; J. ALMEIDA, Auteur ; S. MOUGA, Auteur ; G. OLIVEIRA, Auteur . - p.888-892. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.888-892 Mots-clés : Autism spectrum disorder  Fragile X syndrome  FRAXE  FMR2  Intellectual disability  Compulsive behavior problems Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by impaired social interaction and communication, restricted interests and repetitive behaviors. Fragile X E is associated with X-linked non-specific mild intellectual disability (ID) and with behavioral problems. Most of the known genetic causes of ASD are also causes of ID, implying that these two identities share common genetic bases. We present a child with an ASD with a normal range of intelligence quotient, that later evolved to compulsive behavior. FRAXE locus analysis by polymerase chain reaction revealed a complete mutation of the FMR 2 gene. This report stresses the importance of clinicians being aware of the association between a full mutation of FMR2 and ASD associated with compulsive behavior despite normal intellectual level. En ligne : http://dx.doi.org/10.1007/s10803-014-2185-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258