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Détail de l'auteur
Auteur Karen M. WEIDENHEIM |
Documents disponibles écrits par cet auteur (1)
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Brief Report: Life History and Neuropathology of a Gifted Man with Asperger Syndrome / Karen M. WEIDENHEIM in Journal of Autism and Developmental Disorders, 42-3 (March 2012)
[article]
Titre : Brief Report: Life History and Neuropathology of a Gifted Man with Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Karen M. WEIDENHEIM, Auteur ; Alfonso ESCOBAR, Auteur ; Isabelle RAPIN, Auteur Année de publication : 2012 Article en page(s) : p.460-467 Langues : Anglais (eng) Mots-clés : Autism Asperger syndrome Life history Neuropathology Adult Index. décimale : PER Périodiques Résumé : Despite recent interest in the pathogenesis of the autism spectrum disorders (pervasive developmental disorders), neuropathological descriptions of brains of individuals with well documented clinical information and without potentially confounding symptomatology are exceptionally rare. Asperger syndrome differs from classic autism by lack of cognitive impairment or delay in expressive language acquisition. We examined the 1,570 g brain of a 63 year old otherwise healthy mathematician with an Autistic Spectrum Disorder of Asperger subtype. Except for an atypical gyral pattern and megalencephaly, we detected no specific neuropathologic abnormality. Taken together, the behavioral data and pathological findings in this case are compatible with an early neurodevelopmental process affecting multiple neuroanatomic networks, but without a convincing morphologic signature detectable with routine neuropathologic technology. En ligne : http://dx.doi.org/10.1007/s10803-011-1259-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152
in Journal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.460-467[article] Brief Report: Life History and Neuropathology of a Gifted Man with Asperger Syndrome [Texte imprimé et/ou numérique] / Karen M. WEIDENHEIM, Auteur ; Alfonso ESCOBAR, Auteur ; Isabelle RAPIN, Auteur . - 2012 . - p.460-467.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.460-467
Mots-clés : Autism Asperger syndrome Life history Neuropathology Adult Index. décimale : PER Périodiques Résumé : Despite recent interest in the pathogenesis of the autism spectrum disorders (pervasive developmental disorders), neuropathological descriptions of brains of individuals with well documented clinical information and without potentially confounding symptomatology are exceptionally rare. Asperger syndrome differs from classic autism by lack of cognitive impairment or delay in expressive language acquisition. We examined the 1,570 g brain of a 63 year old otherwise healthy mathematician with an Autistic Spectrum Disorder of Asperger subtype. Except for an atypical gyral pattern and megalencephaly, we detected no specific neuropathologic abnormality. Taken together, the behavioral data and pathological findings in this case are compatible with an early neurodevelopmental process affecting multiple neuroanatomic networks, but without a convincing morphologic signature detectable with routine neuropathologic technology. En ligne : http://dx.doi.org/10.1007/s10803-011-1259-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152