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Détail de l'auteur
Auteur Dana Charles MCCOY
Documents disponibles écrits par cet auteur



Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene / Cynthia J. WILLNER in Development and Psychopathology, 26-4 (Part 1) (November 2014)
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[article]
in Development and Psychopathology > 26-4 (Part 1) (November 2014) . - p.999-1019
Titre : Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene Type de document : texte imprimé Auteurs : Cynthia J. WILLNER, Auteur ; Pamela A. MORRIS, Auteur ; Dana Charles MCCOY, Auteur ; Emma K. ADAM, Auteur Année de publication : 2014 Article en page(s) : p.999-1019 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Building on research on cumulative risk and psychopathology, this study examines how cumulative risk exposure is associated with altered diurnal cortisol rhythms in an ethnically diverse, low-income sample of youth. In addition, consistent with a diathesis-stress perspective, this study explores whether the effect of environmental risk is moderated by allelic variation in the serotonin transporter linked polymorphic region (5-HTTLPR) gene. Results show that youth with greater cumulative risk exposure had flatter diurnal cortisol slopes, regardless of 5-HTTLPR genotype. However, the association of cumulative risk with average cortisol output (area under the curve [AUC]) was moderated by the 5-HTTLPR genotype. Among youth homozygous for the long allele, greater cumulative risk exposure was associated with lower cortisol AUC, driven by significant reductions in cortisol levels at waking. In contrast, there was a trend-level association between greater cumulative risk and higher cortisol AUC among youth carrying the short allele, driven by a trend-level increase in bedtime cortisol levels. Findings are discussed with regard to the relevance of dysregulated diurnal cortisol rhythms for the development of psychopathology and the implications of genetically mediated differences in psychophysiological adaptations to stress. En ligne : http://dx.doi.org/10.1017/S0954579414000558 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2429 [article] Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene [texte imprimé] / Cynthia J. WILLNER, Auteur ; Pamela A. MORRIS, Auteur ; Dana Charles MCCOY, Auteur ; Emma K. ADAM, Auteur . - 2014 . - p.999-1019.
Langues : Anglais (eng)
in Development and Psychopathology > 26-4 (Part 1) (November 2014) . - p.999-1019
Index. décimale : PER Périodiques Résumé : Building on research on cumulative risk and psychopathology, this study examines how cumulative risk exposure is associated with altered diurnal cortisol rhythms in an ethnically diverse, low-income sample of youth. In addition, consistent with a diathesis-stress perspective, this study explores whether the effect of environmental risk is moderated by allelic variation in the serotonin transporter linked polymorphic region (5-HTTLPR) gene. Results show that youth with greater cumulative risk exposure had flatter diurnal cortisol slopes, regardless of 5-HTTLPR genotype. However, the association of cumulative risk with average cortisol output (area under the curve [AUC]) was moderated by the 5-HTTLPR genotype. Among youth homozygous for the long allele, greater cumulative risk exposure was associated with lower cortisol AUC, driven by significant reductions in cortisol levels at waking. In contrast, there was a trend-level association between greater cumulative risk and higher cortisol AUC among youth carrying the short allele, driven by a trend-level increase in bedtime cortisol levels. Findings are discussed with regard to the relevance of dysregulated diurnal cortisol rhythms for the development of psychopathology and the implications of genetically mediated differences in psychophysiological adaptations to stress. En ligne : http://dx.doi.org/10.1017/S0954579414000558 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2429 Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene—ERRATUM / Cynthia J. WILLNER in Development and Psychopathology, 26-4 (Part 1) (November 2014)
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[article]
in Development and Psychopathology > 26-4 (Part 1) (November 2014) . - p.1185-1188
Titre : Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene—ERRATUM Type de document : texte imprimé Auteurs : Cynthia J. WILLNER, Auteur ; Pamela A. MORRIS, Auteur ; Dana Charles MCCOY, Auteur ; Emma K. ADAM, Auteur Année de publication : 2014 Article en page(s) : p.1185-1188 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579414000819 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2430 [article] Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene—ERRATUM [texte imprimé] / Cynthia J. WILLNER, Auteur ; Pamela A. MORRIS, Auteur ; Dana Charles MCCOY, Auteur ; Emma K. ADAM, Auteur . - 2014 . - p.1185-1188.
Langues : Anglais (eng)
in Development and Psychopathology > 26-4 (Part 1) (November 2014) . - p.1185-1188
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579414000819 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2430
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