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Détail de l'auteur
Auteur Keun-Ah CHEON |
Documents disponibles écrits par cet auteur (2)
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Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis / J. Y. KIM in Autism Research, 15-2 (February 2022)
[article]
Titre : Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur Article en page(s) : p.340-352 Langues : Anglais (eng) Mots-clés : Crohn's disease autism spectrum disorder inflammatory bowel disease meta-analysis ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p 0.001; ulcerative colitis, OR = 1.91, 95%CI = 1.41-2.6, p 0.001; Crohn's disease, OR = 1.47, 95%CI = 1.15-1.88, p?= 0.002). ASD and IBD were also associated regardless of temporal sequence of diagnosis (any IBD, OR = 1.57, 95%CI = 1.28-1.93, p 0.001; ulcerative colitis, OR = 1.7, 95%CI = 1.36-2.12, p 0.001; Crohn's disease, OR = 1.37, 95%CI = 1.12-1.69, p?= 0.003). Sensitivity analyses confirmed the findings of the main analysis. Meta-regression did not identify any significant moderators. Publication bias was not detected. Quality was high in four datasets and medium in four. In conclusion, our findings highlight the need to screen for IBD in individuals with ASD, and future research should identify who, among those with ASD, has the highest risk of IBD, and elucidate the shared biological mechanisms between ASD and IBD. LAY SUMMARY: This systematic review and meta-analysis of eight observational datasets found that individuals with autism spectrum disorder (ASD) are more likely to develop any inflammatory bowel disease, ulcerative colitis, or Crohn's disease. Our findings highlight the need to screen for inflammatory bowel disease in patients with ASD and elucidate the shared biological mechanisms between the two disorders. En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450
in Autism Research > 15-2 (February 2022) . - p.340-352[article] Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur . - p.340-352.
Langues : Anglais (eng)
in Autism Research > 15-2 (February 2022) . - p.340-352
Mots-clés : Crohn's disease autism spectrum disorder inflammatory bowel disease meta-analysis ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p 0.001; ulcerative colitis, OR = 1.91, 95%CI = 1.41-2.6, p 0.001; Crohn's disease, OR = 1.47, 95%CI = 1.15-1.88, p?= 0.002). ASD and IBD were also associated regardless of temporal sequence of diagnosis (any IBD, OR = 1.57, 95%CI = 1.28-1.93, p 0.001; ulcerative colitis, OR = 1.7, 95%CI = 1.36-2.12, p 0.001; Crohn's disease, OR = 1.37, 95%CI = 1.12-1.69, p?= 0.003). Sensitivity analyses confirmed the findings of the main analysis. Meta-regression did not identify any significant moderators. Publication bias was not detected. Quality was high in four datasets and medium in four. In conclusion, our findings highlight the need to screen for IBD in individuals with ASD, and future research should identify who, among those with ASD, has the highest risk of IBD, and elucidate the shared biological mechanisms between ASD and IBD. LAY SUMMARY: This systematic review and meta-analysis of eight observational datasets found that individuals with autism spectrum disorder (ASD) are more likely to develop any inflammatory bowel disease, ulcerative colitis, or Crohn's disease. Our findings highlight the need to screen for inflammatory bowel disease in patients with ASD and elucidate the shared biological mechanisms between the two disorders. En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children / Keun-Ah CHEON in Autism Research, 9-9 (September 2016)
[article]
Titre : The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children Type de document : Texte imprimé et/ou numérique Auteurs : Keun-Ah CHEON, Auteur ; Jee-In PARK, Auteur ; Yun-Joo KOH, Auteur ; Jungeun SONG, Auteur ; Hyun-Joo HONG, Auteur ; Young-Kee KIM, Auteur ; Eun-Chung LIM, Auteur ; Hojang KWON, Auteur ; Mina HA, Auteur ; Myung-Ho LIM, Auteur ; Ki-Chung PAIK, Auteur ; John N. CONSTANTINO, Auteur ; Bennett L. LEVENTHAL, Auteur ; Young Shin KIM, Auteur Article en page(s) : p.970-980 Langues : Anglais (eng) Mots-clés : Korean social responsiveness scale validity reliability DSM IV PDD DSM5 ASD Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version (K-SRS).The study subjects were ascertained from three samples: a general sample from 3 regular education elementary schools (n=790), a clinical sample (n=154) of 6–12-year-olds from four psychiatric clinics, and an epidemiological sample of children with ASD, diagnosed using both DSM IV PDD, DSM5 ASD and SCD criteria (n=151). Their parents completed the K-SRS and the Autism Spectrum Screening Questionnaire(ASSQ). Descriptive statistics, correlation analyses and principal components analysis (PCA) were performed on the total population. Mean total scores on the K-SRS differed significantly between the three samples. ASSQ scores were significantly correlated with the K-SRS T-scores. PCA suggested a one-factor solution for the total population.Our results indicate that the K-SRS exhibits adequate reliability and validity for measuring ASD symptoms in Korean children with DSM IV PDD and DSM5 ASD. Our findings further suggest that it is difficult to distinguish SCD from other child psychiatric conditions using the K-SRS.This is the first study to examine the relationship between the SRS subscales and DSM5-based clinical diagnoses. This study provides cross-cultural confirmation of the factor structure for ASD symptoms and traits measured by the SRS. Autism Res 2016, 9: 970–980. En ligne : http://dx.doi.org/10.1002/aur.1671 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294
in Autism Research > 9-9 (September 2016) . - p.970-980[article] The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children [Texte imprimé et/ou numérique] / Keun-Ah CHEON, Auteur ; Jee-In PARK, Auteur ; Yun-Joo KOH, Auteur ; Jungeun SONG, Auteur ; Hyun-Joo HONG, Auteur ; Young-Kee KIM, Auteur ; Eun-Chung LIM, Auteur ; Hojang KWON, Auteur ; Mina HA, Auteur ; Myung-Ho LIM, Auteur ; Ki-Chung PAIK, Auteur ; John N. CONSTANTINO, Auteur ; Bennett L. LEVENTHAL, Auteur ; Young Shin KIM, Auteur . - p.970-980.
Langues : Anglais (eng)
in Autism Research > 9-9 (September 2016) . - p.970-980
Mots-clés : Korean social responsiveness scale validity reliability DSM IV PDD DSM5 ASD Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version (K-SRS).The study subjects were ascertained from three samples: a general sample from 3 regular education elementary schools (n=790), a clinical sample (n=154) of 6–12-year-olds from four psychiatric clinics, and an epidemiological sample of children with ASD, diagnosed using both DSM IV PDD, DSM5 ASD and SCD criteria (n=151). Their parents completed the K-SRS and the Autism Spectrum Screening Questionnaire(ASSQ). Descriptive statistics, correlation analyses and principal components analysis (PCA) were performed on the total population. Mean total scores on the K-SRS differed significantly between the three samples. ASSQ scores were significantly correlated with the K-SRS T-scores. PCA suggested a one-factor solution for the total population.Our results indicate that the K-SRS exhibits adequate reliability and validity for measuring ASD symptoms in Korean children with DSM IV PDD and DSM5 ASD. Our findings further suggest that it is difficult to distinguish SCD from other child psychiatric conditions using the K-SRS.This is the first study to examine the relationship between the SRS subscales and DSM5-based clinical diagnoses. This study provides cross-cultural confirmation of the factor structure for ASD symptoms and traits measured by the SRS. Autism Res 2016, 9: 970–980. En ligne : http://dx.doi.org/10.1002/aur.1671 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294