Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur J. BREDDY |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life / Carmen Maria SCHRODER in Journal of Autism and Developmental Disorders, 49-8 (August 2019)
[article]
Titre : Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life Type de document : Texte imprimé et/ou numérique Auteurs : Carmen Maria SCHRODER, Auteur ; B. A. MALOW, Auteur ; A. MARAS, Auteur ; R. D. MELMED, Auteur ; R. L. FINDLING, Auteur ; J. BREDDY, Auteur ; T. NIR, Auteur ; S. SHAHMOON, Auteur ; N. ZISAPEL, Auteur ; P. GRINGRAS, Auteur Article en page(s) : p.3218-3230 Langues : Anglais (eng) Mots-clés : Autism Behavior Children (pediatric) Prolonged-release melatonin Sleep Index. décimale : PER Périodiques Résumé : A randomized, 13-weeks, placebo-controlled double-blind study in 125 subjects aged 2-17.5 years with Autism Spectrum Disorder or Smith-Magenis syndrome and insomnia demonstrated efficacy and safety of easily-swallowed prolonged-release melatonin mini-tablets (PedPRM; 2-5 mg) in improving sleep duration and onset. Treatment effects on child behavior and caregiver's quality of life were evaluated. PedPRM treatment resulted in significant improvement in externalizing but not internalizing behavior (Strengths and Difficulties questionnaire; SDQ) compared to placebo (p = 0.021) with clinically-relevant improvements in 53.7% of PedPRM-treated versus 27.6% of placebo-treated subjects (p = 0.008). Caregivers' quality of life also improved with PedPRM versus placebo (p = 0.010) and correlated with the change in total SDQ (p = 0.0005). PedPRM alleviates insomnia-related difficulties, particularly externalizing behavior in the children, subsequently improving caregivers' quality of life. En ligne : http://dx.doi.org/10.1007/s10803-019-04046-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403
in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3218-3230[article] Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life [Texte imprimé et/ou numérique] / Carmen Maria SCHRODER, Auteur ; B. A. MALOW, Auteur ; A. MARAS, Auteur ; R. D. MELMED, Auteur ; R. L. FINDLING, Auteur ; J. BREDDY, Auteur ; T. NIR, Auteur ; S. SHAHMOON, Auteur ; N. ZISAPEL, Auteur ; P. GRINGRAS, Auteur . - p.3218-3230.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3218-3230
Mots-clés : Autism Behavior Children (pediatric) Prolonged-release melatonin Sleep Index. décimale : PER Périodiques Résumé : A randomized, 13-weeks, placebo-controlled double-blind study in 125 subjects aged 2-17.5 years with Autism Spectrum Disorder or Smith-Magenis syndrome and insomnia demonstrated efficacy and safety of easily-swallowed prolonged-release melatonin mini-tablets (PedPRM; 2-5 mg) in improving sleep duration and onset. Treatment effects on child behavior and caregiver's quality of life were evaluated. PedPRM treatment resulted in significant improvement in externalizing but not internalizing behavior (Strengths and Difficulties questionnaire; SDQ) compared to placebo (p = 0.021) with clinically-relevant improvements in 53.7% of PedPRM-treated versus 27.6% of placebo-treated subjects (p = 0.008). Caregivers' quality of life also improved with PedPRM versus placebo (p = 0.010) and correlated with the change in total SDQ (p = 0.0005). PedPRM alleviates insomnia-related difficulties, particularly externalizing behavior in the children, subsequently improving caregivers' quality of life. En ligne : http://dx.doi.org/10.1007/s10803-019-04046-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403