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Auteur Francisco DIAZ ATIENZA |
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Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial / Pablo Jose GONZALEZ-DOMENECH in Journal of Autism and Developmental Disorders, 50-3 (March 2020)
[article]
Titre : Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial Type de document : Texte imprimé et/ou numérique Auteurs : Pablo Jose GONZALEZ-DOMENECH, Auteur ; Francisco DIAZ ATIENZA, Auteur ; Carlos GARCIA PABLOS, Auteur ; Maria Luisa FERNANDEZ SOTO, Auteur ; Jose Maria MARTINEZ-ORTEGA, Auteur ; Luis GUTIERREZ-ROJAS, Auteur Article en page(s) : p.935-948 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Beta-casomorphin Casein Diet Gluten Index. décimale : PER Périodiques Résumé : The use of alternative interventions, such as gluten-free and casein-free (GFCF) diets, is frequent due to limited therapies for Autism Spectrum Disorder (ASD). Our aims were to determine the influence of a GFCF diet on behavior disorders in children and adolescents diagnosed with ASD and the potential association with urinary beta-casomorphin concentrations. Thirty-seven patients were recruited for this crossover trial. Each patient consumed a normal diet (including gluten and casein) for 6 months and a GFCF diet for another 6 months. The order of the intervention (beginning with normal diet or with GFCF diet) was assigned randomly. Patients were evaluated at three time-points (at the beginning of the study, after normal diet and after GFCF diet). Questionnaires regarding behavior and autism and dietary adherence were completed and urinary beta-casomorphin concentrations were determined at each time-point. No significant behavioral changes and no association with urinary beta-casomorphin concentrations were found after GFCF diet. A 6-month GFCF diet do not induce significant changes in behavioral symptoms of autism and urinary beta-casomorphin concentrations. Further studies with a long follow-up period similar to ours and including placebo and blinding elements are needed to identify better those respondents to GFCF diets. En ligne : http://dx.doi.org/10.1007/s10803-019-04333-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419
in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.935-948[article] Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial [Texte imprimé et/ou numérique] / Pablo Jose GONZALEZ-DOMENECH, Auteur ; Francisco DIAZ ATIENZA, Auteur ; Carlos GARCIA PABLOS, Auteur ; Maria Luisa FERNANDEZ SOTO, Auteur ; Jose Maria MARTINEZ-ORTEGA, Auteur ; Luis GUTIERREZ-ROJAS, Auteur . - p.935-948.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.935-948
Mots-clés : Autism spectrum disorder Beta-casomorphin Casein Diet Gluten Index. décimale : PER Périodiques Résumé : The use of alternative interventions, such as gluten-free and casein-free (GFCF) diets, is frequent due to limited therapies for Autism Spectrum Disorder (ASD). Our aims were to determine the influence of a GFCF diet on behavior disorders in children and adolescents diagnosed with ASD and the potential association with urinary beta-casomorphin concentrations. Thirty-seven patients were recruited for this crossover trial. Each patient consumed a normal diet (including gluten and casein) for 6 months and a GFCF diet for another 6 months. The order of the intervention (beginning with normal diet or with GFCF diet) was assigned randomly. Patients were evaluated at three time-points (at the beginning of the study, after normal diet and after GFCF diet). Questionnaires regarding behavior and autism and dietary adherence were completed and urinary beta-casomorphin concentrations were determined at each time-point. No significant behavioral changes and no association with urinary beta-casomorphin concentrations were found after GFCF diet. A 6-month GFCF diet do not induce significant changes in behavioral symptoms of autism and urinary beta-casomorphin concentrations. Further studies with a long follow-up period similar to ours and including placebo and blinding elements are needed to identify better those respondents to GFCF diets. En ligne : http://dx.doi.org/10.1007/s10803-019-04333-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419