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Détail de l'auteur
Auteur Mohammad EFTEKHAR |
Documents disponibles écrits par cet auteur (1)
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Sexual Dimorphism in Telomere Length in Childhood Autism / Yasin PANAHI in Journal of Autism and Developmental Disorders, 53-5 (May 2023)
[article]
Titre : Sexual Dimorphism in Telomere Length in Childhood Autism Type de document : Texte imprimé et/ou numérique Auteurs : Yasin PANAHI, Auteur ; Fahimeh SALASAR MOGHADDAM, Auteur ; Khadijeh BABAEI, Auteur ; Mohammad EFTEKHAR, Auteur ; Reza SHERVIN BADV, Auteur ; Mohammad Reza ESKANDARI, Auteur ; Mohammad VAFAEE-SHAHI, Auteur ; Hamid PEZESHK, Auteur ; Mehrdad PEDRAM, Auteur Article en page(s) : p.2050-2061 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are strikingly more prevalent in males, but the molecular mechanisms responsible for ASD sex-differential risk are poorly understood. Abnormally shorter telomeres have been associated with autism. Examination of relative telomere lengths (RTL) among non-syndromic male (N=14) and female (N=10) children with autism revealed that only autistic male children had significantly shorter RTL than typically-developing controls (N=24) and paired siblings (N=10). While average RTL of autistic girls did not differ significantly from controls, it was substantially longer than autistic boys. Our findings indicate a sexually-dimorphic pattern of RTL in childhood autism and could have important implications for RTL as a potential biomarker and the role/s of telomeres in the molecular mechanisms responsible for ASD sex-biased prevalence and etiology. En ligne : https://doi.org/10.1007/s10803-022-05486-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501
in Journal of Autism and Developmental Disorders > 53-5 (May 2023) . - p.2050-2061[article] Sexual Dimorphism in Telomere Length in Childhood Autism [Texte imprimé et/ou numérique] / Yasin PANAHI, Auteur ; Fahimeh SALASAR MOGHADDAM, Auteur ; Khadijeh BABAEI, Auteur ; Mohammad EFTEKHAR, Auteur ; Reza SHERVIN BADV, Auteur ; Mohammad Reza ESKANDARI, Auteur ; Mohammad VAFAEE-SHAHI, Auteur ; Hamid PEZESHK, Auteur ; Mehrdad PEDRAM, Auteur . - p.2050-2061.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-5 (May 2023) . - p.2050-2061
Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are strikingly more prevalent in males, but the molecular mechanisms responsible for ASD sex-differential risk are poorly understood. Abnormally shorter telomeres have been associated with autism. Examination of relative telomere lengths (RTL) among non-syndromic male (N=14) and female (N=10) children with autism revealed that only autistic male children had significantly shorter RTL than typically-developing controls (N=24) and paired siblings (N=10). While average RTL of autistic girls did not differ significantly from controls, it was substantially longer than autistic boys. Our findings indicate a sexually-dimorphic pattern of RTL in childhood autism and could have important implications for RTL as a potential biomarker and the role/s of telomeres in the molecular mechanisms responsible for ASD sex-biased prevalence and etiology. En ligne : https://doi.org/10.1007/s10803-022-05486-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501