58 recherche sur le mot-clé 'ALSPAC'

Adolescent eating behaviours: associations with autistic and ADHD traits in childhood and the mediating role of anxiety / Johanna KELLER in Journal of Child Psychology and Psychiatry, 67-3 (March 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-3 (March 2026) . - p.344-354 Titre : Adolescent eating behaviours: associations with autistic and ADHD traits in childhood and the mediating role of anxiety Type de document : texte imprimé Auteurs : Johanna KELLER, Auteur ; William Polmear Locke MANDY, Auteur ; Moritz HERLE, Auteur ; Virginia CARTER LENO, Auteur Article en page(s) : p.344-354 Langues : Anglais (eng) Mots-clés : Autism  ADHD  eating disorder  anxiety  gender  ALSPAC Index. décimale : PER Périodiques Résumé : Background Autistic individuals and individuals with ADHD are more likely to experience eating disorders, yet the reasons for this are not well understood. We investigated whether childhood neurodivergent (i.e. autistic and ADHD) traits are associated with patterns of emotional/restrained eating and externally driven eating behaviours in adolescence, whether these associations differed by sex and if they are mediated by anxiety. Methods We tested the association between parent-reported childhood (age 7?years) autistic and ADHD (i.e. hyperactivity/impulsivity, inattention) traits and self-reported adolescent (age 13) eating behaviours in a large population-representative prospective cohort (N?=?7,572; Avon Longitudinal Study of Parents and Children). We performed multi-group longitudinal analysis stratified by sex to understand whether sex moderates' associations between neurodevelopmental traits and adolescent eating behaviours. Mediation models tested the extent to which observed associations were driven by mid-childhood (age 10) anxiety symptoms. All analyses were adjusted for child sex, child ethnicity, maternal education levels and maternal age at birth. Results Individuals who had higher childhood autistic traits were more likely to report emotional/restrained (b?=?0.59, 95% CI [0.29, 0.88], p? En ligne : https://doi.org/10.1111/jcpp.70051 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=580 [article] Adolescent eating behaviours: associations with autistic and ADHD traits in childhood and the mediating role of anxiety [texte imprimé] / Johanna KELLER, Auteur ; William Polmear Locke MANDY, Auteur ; Moritz HERLE, Auteur ; Virginia CARTER LENO, Auteur . - p.344-354. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-3 (March 2026) . - p.344-354 Mots-clés : Autism  ADHD  eating disorder  anxiety  gender  ALSPAC Index. décimale : PER Périodiques Résumé : Background Autistic individuals and individuals with ADHD are more likely to experience eating disorders, yet the reasons for this are not well understood. We investigated whether childhood neurodivergent (i.e. autistic and ADHD) traits are associated with patterns of emotional/restrained eating and externally driven eating behaviours in adolescence, whether these associations differed by sex and if they are mediated by anxiety. Methods We tested the association between parent-reported childhood (age 7?years) autistic and ADHD (i.e. hyperactivity/impulsivity, inattention) traits and self-reported adolescent (age 13) eating behaviours in a large population-representative prospective cohort (N?=?7,572; Avon Longitudinal Study of Parents and Children). We performed multi-group longitudinal analysis stratified by sex to understand whether sex moderates' associations between neurodevelopmental traits and adolescent eating behaviours. Mediation models tested the extent to which observed associations were driven by mid-childhood (age 10) anxiety symptoms. All analyses were adjusted for child sex, child ethnicity, maternal education levels and maternal age at birth. Results Individuals who had higher childhood autistic traits were more likely to report emotional/restrained (b?=?0.59, 95% CI [0.29, 0.88], p? En ligne : https://doi.org/10.1111/jcpp.70051 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=580

Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population / Elise B. ROBINSON in Journal of Autism and Developmental Disorders, 41-12 (December 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737 Titre : Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population Type de document : texte imprimé Auteurs : Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur Année de publication : 2011 Article en page(s) : p.1733-1737 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Autistic traits  Parental age  ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 [article] Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population [texte imprimé] / Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur . - 2011 . - p.1733-1737. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737 Mots-clés : Autism spectrum disorders  Autistic traits  Parental age  ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148

Bullied by peers in childhood and borderline personality symptoms at 11 years of age: A prospective study / Dieter WOLKE in Journal of Child Psychology and Psychiatry, 53-8 (August 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-8 (August 2012) . - p.846-855 Titre : Bullied by peers in childhood and borderline personality symptoms at 11 years of age: A prospective study Type de document : texte imprimé Auteurs : Dieter WOLKE, Auteur ; Andrea SCHREIER, Auteur ; Mary C. ZANARINI, Auteur ; Catherine WINSPER, Auteur Année de publication : 2012 Article en page(s) : p.846-855 Langues : Anglais (eng) Mots-clés : ALSPAC  bullying  borderline personality disorder  victimisation  peer relationships Index. décimale : PER Périodiques Résumé : Background:  Abuse by adults has been reported as a potent predictor of borderline personality disorder (BPD). Unclear is whether victimisation by peers increases the risk of borderline personality symptoms. Method:  The Avon Longitudinal Study of Parents and Children (ALSPAC) prospective, longitudinal observation study of 6050 mothers and their children. Child bullying was measured by self-report and mother and teacher report between 4 and 10 years. Family adversity was assessed from pregnancy to 4 years; parenting behaviours from 2 to 7 years, sexual abuse from 1.5 to 9 years, and IQ and DSM-IV axis I diagnoses at 7 to 8 years. Trained psychologists interviewed children at 11.8 years to ascertain DSM-IV BPD symptoms (five or more). Results:  Accounting for known confounders, victims of peer bullying had an increased risk of BPD symptoms according to self-report (OR, 2.82; 95% CI, 2.13–3.72); mother report (OR, 2.43; 95% CI, 1.86–3.16); and teacher report (OR, 1.95; 95% CI, 1.34–2.83). Children who reported being chronically bullied (OR, 5.44; 95% CI, 3.86–7.66) or experienced combined relational and overt victimisation (OR, 7.10; 95% CI, 4.79–10.51) had highly increased odds of developing BPD symptoms. Children exposed to chronic victimisation according to mother report were also at heightened risk of developing BPD symptoms (OR, 3.24; 95% CI, 2.24–4.68). Conclusions:  Intentional harm inflicted by peers is a precursor or marker on the trajectory towards the development of BPD symptoms in childhood. Clinicians should be adequately trained to deal with, and ask users of mental health services routinely about, adverse experiences with peers. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02542.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=177 [article] Bullied by peers in childhood and borderline personality symptoms at 11 years of age: A prospective study [texte imprimé] / Dieter WOLKE, Auteur ; Andrea SCHREIER, Auteur ; Mary C. ZANARINI, Auteur ; Catherine WINSPER, Auteur . - 2012 . - p.846-855. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-8 (August 2012) . - p.846-855 Mots-clés : ALSPAC  bullying  borderline personality disorder  victimisation  peer relationships Index. décimale : PER Périodiques Résumé : Background:  Abuse by adults has been reported as a potent predictor of borderline personality disorder (BPD). Unclear is whether victimisation by peers increases the risk of borderline personality symptoms. Method:  The Avon Longitudinal Study of Parents and Children (ALSPAC) prospective, longitudinal observation study of 6050 mothers and their children. Child bullying was measured by self-report and mother and teacher report between 4 and 10 years. Family adversity was assessed from pregnancy to 4 years; parenting behaviours from 2 to 7 years, sexual abuse from 1.5 to 9 years, and IQ and DSM-IV axis I diagnoses at 7 to 8 years. Trained psychologists interviewed children at 11.8 years to ascertain DSM-IV BPD symptoms (five or more). Results:  Accounting for known confounders, victims of peer bullying had an increased risk of BPD symptoms according to self-report (OR, 2.82; 95% CI, 2.13–3.72); mother report (OR, 2.43; 95% CI, 1.86–3.16); and teacher report (OR, 1.95; 95% CI, 1.34–2.83). Children who reported being chronically bullied (OR, 5.44; 95% CI, 3.86–7.66) or experienced combined relational and overt victimisation (OR, 7.10; 95% CI, 4.79–10.51) had highly increased odds of developing BPD symptoms. Children exposed to chronic victimisation according to mother report were also at heightened risk of developing BPD symptoms (OR, 3.24; 95% CI, 2.24–4.68). Conclusions:  Intentional harm inflicted by peers is a precursor or marker on the trajectory towards the development of BPD symptoms in childhood. Clinicians should be adequately trained to deal with, and ask users of mental health services routinely about, adverse experiences with peers. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02542.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=177

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability / Olga EYRE in Journal of Child Psychology and Psychiatry, 60-8 (August 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.866-874 Titre : Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability Type de document : texte imprimé Auteurs : Olga EYRE, Auteur ; Rachael A. HUGHES, Auteur ; Ajay K. THAPAR, Auteur ; Ellen LEIBENLUFT, Auteur ; Argyris STRINGARIS, Auteur ; George DAVEY SMITH, Auteur ; Evangelia STERGIAKOULI, Auteur ; Stephan COLLISHAW, Auteur ; Anita THAPAR, Auteur Article en page(s) : p.866-874 Langues : Anglais (eng) Mots-clés : Alspac  attention-deficit/hyperactivity disorder  autism  depression  irritability  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with neurodevelopmental disorders are at increased risk of developing depression. Irritability predicts depression in the general population and is common in children with neurodevelopmental disorders. Thus, it is possible that irritability in children with neurodevelopmental disorders contributes to the link with later depression. This study aimed to (a) examine the association between childhood neurodevelopmental difficulties and adolescent depression and (b) test whether irritability explains this association. METHODS: Children with any neurodevelopmental difficulty at the age of 7-9 (n = 1,697) and a selected, comparison group without any neurodevelopmental difficulty (n = 3,177) were identified from a prospective, UK population-based cohort, the Avon Longitudinal Study of Parents and Children. Neurodevelopmental difficulties were defined as a score in the bottom 5% of the sample on at least one measure of cognitive ability, communication, autism spectrum symptoms, attention-deficit/hyperactivity symptoms, reading or motor coordination. The Development and Well-Being Assessment measured parent-reported child irritability at the age of 7, parent-reported adolescent depression at the age of 10 and 13, and self-reported depression at the age of 15. Depression measures were combined, deriving an outcome of major depressive disorder (MDD) in adolescence. Logistic regression examined the association between childhood neurodevelopmental difficulties and adolescent MDD, controlling for gender. Path analysis estimated the proportion of this association explained by irritability. Analyses were repeated for individual neurodevelopmental problems. RESULTS: Childhood neurodevelopmental difficulties were associated with adolescent MDD (OR = 2.11, 95% CI = 1.24, 3.60, p = .006). Childhood irritability statistically accounted for 42% of this association. On examining each neurodevelopmental difficulty separately, autistic, communication and ADHD problems were each associated with depression, with irritability explaining 29%-51% of these links. CONCLUSIONS: Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group. En ligne : http://dx.doi.org/10.1111/jcpp.13053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404 [article] Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability [texte imprimé] / Olga EYRE, Auteur ; Rachael A. HUGHES, Auteur ; Ajay K. THAPAR, Auteur ; Ellen LEIBENLUFT, Auteur ; Argyris STRINGARIS, Auteur ; George DAVEY SMITH, Auteur ; Evangelia STERGIAKOULI, Auteur ; Stephan COLLISHAW, Auteur ; Anita THAPAR, Auteur . - p.866-874. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.866-874 Mots-clés : Alspac  attention-deficit/hyperactivity disorder  autism  depression  irritability  neurodevelopmental Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with neurodevelopmental disorders are at increased risk of developing depression. Irritability predicts depression in the general population and is common in children with neurodevelopmental disorders. Thus, it is possible that irritability in children with neurodevelopmental disorders contributes to the link with later depression. This study aimed to (a) examine the association between childhood neurodevelopmental difficulties and adolescent depression and (b) test whether irritability explains this association. METHODS: Children with any neurodevelopmental difficulty at the age of 7-9 (n = 1,697) and a selected, comparison group without any neurodevelopmental difficulty (n = 3,177) were identified from a prospective, UK population-based cohort, the Avon Longitudinal Study of Parents and Children. Neurodevelopmental difficulties were defined as a score in the bottom 5% of the sample on at least one measure of cognitive ability, communication, autism spectrum symptoms, attention-deficit/hyperactivity symptoms, reading or motor coordination. The Development and Well-Being Assessment measured parent-reported child irritability at the age of 7, parent-reported adolescent depression at the age of 10 and 13, and self-reported depression at the age of 15. Depression measures were combined, deriving an outcome of major depressive disorder (MDD) in adolescence. Logistic regression examined the association between childhood neurodevelopmental difficulties and adolescent MDD, controlling for gender. Path analysis estimated the proportion of this association explained by irritability. Analyses were repeated for individual neurodevelopmental problems. RESULTS: Childhood neurodevelopmental difficulties were associated with adolescent MDD (OR = 2.11, 95% CI = 1.24, 3.60, p = .006). Childhood irritability statistically accounted for 42% of this association. On examining each neurodevelopmental difficulty separately, autistic, communication and ADHD problems were each associated with depression, with irritability explaining 29%-51% of these links. CONCLUSIONS: Childhood irritability appears to be a key contributor to the link between childhood neurodevelopmental difficulties and adolescent MDD. High rates of irritability in children with autistic and ADHD difficulties may explain elevated rates of depression in the neurodevelopmental group. En ligne : http://dx.doi.org/10.1111/jcpp.13053 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404

Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms / Nadia MICALI in Journal of Child Psychology and Psychiatry, 55-2 (February 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.124-134 Titre : Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms Type de document : texte imprimé Auteurs : Nadia MICALI, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur ; Emily SIMONOFF, Auteur Article en page(s) : p.124-134 Langues : Anglais (eng) Mots-clés : ALSPAC  child psychopathology  eating disorders  parental mental health  risk mechanisms Index. décimale : PER Périodiques Résumé : Background Very few studies have investigated psychopathology in children of mothers with eating disorders (ED). We aimed to determine the effect of maternal ED on childhood psychopathology in a large population-based cohort and investigate relevant risk pathways using structural equation modeling (SEM). Methods Data on emotional and behavioral problems at 3½ years were obtained prospectively on 8,622 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children of exposed women who self-reported lifetime anorexia nervosa (AN, N = 193) or bulimia nervosa (BN, N = 158) in pregnancy were compared with children of unexposed women (N = 8,271) using linear and logistic regression models. SEM was used to determine best-fitting risk models by child gender. Results There was evidence that girls of AN women were more likely to have emotional, conduct, and hyperactivity disorders [Odds Ratio (OR): 1.7 (95% Confidence Intervals 1.0–3.0); OR: 2.2 (1.2–4.0); OR: 1.8 (1.1–3.1), respectively] and boys of AN women to have emotional disorders compared with unexposed [OR: 2.0(1.2–3.4)]. Girls of women with BN were more likely to show hyperactivity [OR: 1.7 (1.0–3.1)]; and boys to show emotional and conduct disorders compared with unexposed [OR: 2.2 (1.2–3.9); OR: 2.4 (1.4–4.2), respectively]. SEM models showed that pregnancy anxiety and depression mediated the effect of maternal ED on child psychopathology. Conclusions Maternal ED are associated with different childhood psychopathology outcomes in boys and girls. Pregnancy anxiety and depression and active ED symptoms are important mediators of risk and are preventable; the direct effect of maternal lifetime ED was small. En ligne : http://dx.doi.org/10.1111/jcpp.12112 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Childhood psychopathology in children of women with eating disorders: understanding risk mechanisms [texte imprimé] / Nadia MICALI, Auteur ; Daniel STAHL, Auteur ; Janet TREASURE, Auteur ; Emily SIMONOFF, Auteur . - p.124-134. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-2 (February 2014) . - p.124-134 Mots-clés : ALSPAC  child psychopathology  eating disorders  parental mental health  risk mechanisms Index. décimale : PER Périodiques Résumé : Background Very few studies have investigated psychopathology in children of mothers with eating disorders (ED). We aimed to determine the effect of maternal ED on childhood psychopathology in a large population-based cohort and investigate relevant risk pathways using structural equation modeling (SEM). Methods Data on emotional and behavioral problems at 3½ years were obtained prospectively on 8,622 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children of exposed women who self-reported lifetime anorexia nervosa (AN, N = 193) or bulimia nervosa (BN, N = 158) in pregnancy were compared with children of unexposed women (N = 8,271) using linear and logistic regression models. SEM was used to determine best-fitting risk models by child gender. Results There was evidence that girls of AN women were more likely to have emotional, conduct, and hyperactivity disorders [Odds Ratio (OR): 1.7 (95% Confidence Intervals 1.0–3.0); OR: 2.2 (1.2–4.0); OR: 1.8 (1.1–3.1), respectively] and boys of AN women to have emotional disorders compared with unexposed [OR: 2.0(1.2–3.4)]. Girls of women with BN were more likely to show hyperactivity [OR: 1.7 (1.0–3.1)]; and boys to show emotional and conduct disorders compared with unexposed [OR: 2.2 (1.2–3.9); OR: 2.4 (1.4–4.2), respectively]. SEM models showed that pregnancy anxiety and depression mediated the effect of maternal ED on child psychopathology. Conclusions Maternal ED are associated with different childhood psychopathology outcomes in boys and girls. Pregnancy anxiety and depression and active ED symptoms are important mediators of risk and are preventable; the direct effect of maternal lifetime ED was small. En ligne : http://dx.doi.org/10.1111/jcpp.12112 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

Childhood psychopathology mediates associations between childhood adversities and multiple health risk behaviours in adolescence: analysis using the ALSPAC birth cohort / David TROY in Journal of Child Psychology and Psychiatry, 62-9 (September 2021)  

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Developing language in a developing body: genetic associations of infant gross motor behaviour and self-care/symbolic actions with emerging language abilities / Ellen VERHOEF in Journal of Child Psychology and Psychiatry, 67-1 (January 2026)  

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Developmental epigenomic effects of maternal financial problems / Cyrielle HOLUKA in Development and Psychopathology, 37-2 (May 2025)  

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Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children / Simone BREIDER in Journal of Autism and Developmental Disorders, 52-6 (June 2022)  

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Emotional problems and peer victimization in adolescents born very preterm and full-term: Role of self-control skills in childhood / Ayten BILGIN in Development and Psychopathology, 36-1 (February 2024)  

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