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The prodrome of autism: early behavioral and biological signs, regression, peri- and post-natal development and genetics / Nurit YIRMIYA in Journal of Child Psychology and Psychiatry, 51-4 (April 2010)
[article]
Titre : The prodrome of autism: early behavioral and biological signs, regression, peri- and post-natal development and genetics Type de document : Texte imprimé et/ou numérique Auteurs : Nurit YIRMIYA, Auteur ; Tony CHARMAN, Auteur Année de publication : 2010 Article en page(s) : p.432-458 Langues : Anglais (eng) Mots-clés : Autism-spectrum-disorders early-markers genetics brain-development siblings perinatal-development diagnosis Index. décimale : PER Périodiques Résumé : Autism is one of the most heritable neurodevelopmental conditions and has an early onset, with symptoms being required to be present in the first 3 years of life in order to meet criteria for the 'core' disorder in the classification systems. As such, the focus on identifying a prodrome over the past 20 years has been on pre-clinical signs or indicators that will be present very early in life, certainly in infancy. A number of novel lines of investigation have been used to this end, including retrospective coding of home videos, prospective population screening and 'high risk' sibling studies; as well as the investigation of pre- and peri-natal, brain developmental and other biological factors. While no single prodromal sign is expected to be present in all cases, a picture is emerging of indicative prodromal signs in infancy and initial studies are being undertaken to attempt to ameliorate early presentation and even 'prevent' emergence of the full syndrome. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02214.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=989
in Journal of Child Psychology and Psychiatry > 51-4 (April 2010) . - p.432-458[article] The prodrome of autism: early behavioral and biological signs, regression, peri- and post-natal development and genetics [Texte imprimé et/ou numérique] / Nurit YIRMIYA, Auteur ; Tony CHARMAN, Auteur . - 2010 . - p.432-458.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 51-4 (April 2010) . - p.432-458
Mots-clés : Autism-spectrum-disorders early-markers genetics brain-development siblings perinatal-development diagnosis Index. décimale : PER Périodiques Résumé : Autism is one of the most heritable neurodevelopmental conditions and has an early onset, with symptoms being required to be present in the first 3 years of life in order to meet criteria for the 'core' disorder in the classification systems. As such, the focus on identifying a prodrome over the past 20 years has been on pre-clinical signs or indicators that will be present very early in life, certainly in infancy. A number of novel lines of investigation have been used to this end, including retrospective coding of home videos, prospective population screening and 'high risk' sibling studies; as well as the investigation of pre- and peri-natal, brain developmental and other biological factors. While no single prodromal sign is expected to be present in all cases, a picture is emerging of indicative prodromal signs in infancy and initial studies are being undertaken to attempt to ameliorate early presentation and even 'prevent' emergence of the full syndrome. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02214.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=989