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Quantitative Assessment of Autism Symptom-related Traits in Probands and Parents: Broader Phenotype Autism Symptom Scale / Geraldine DAWSON in Journal of Autism and Developmental Disorders, 37-3 (March 2007)
[article]
Titre : Quantitative Assessment of Autism Symptom-related Traits in Probands and Parents: Broader Phenotype Autism Symptom Scale Type de document : Texte imprimé et/ou numérique Auteurs : Geraldine DAWSON, Auteur ; Annette ESTES, Auteur ; Jeffrey MUNSON, Auteur ; Gerard SCHELLENBERG, Auteur ; Raphael BERNIER, Auteur ; Robert ABBOTT, Auteur Année de publication : 2007 Article en page(s) : p.523-536 Langues : Anglais (eng) Mots-clés : Broader-phenotype Genetics Quantitative-traits Index. décimale : PER Périodiques Résumé : Autism susceptibility genes likely have effects on continuously distributed autism-related traits, yet few measures of such traits exist. The Broader Phenotype Autism Symptom Scale (BPASS), developed for use with affected children and family members, measures social motivation, social expressiveness, conversational skills, and flexibility. Based on 201 multiplex families, psychometric data on the BPASS are reported. Adequate inter-rater reliability and internal consistency were found. Parents had lower BPASS scores than affected children, after controlling for IQ. Parents and affected children showed overlapping distributions suggesting the BPASS captured variability in traits across groups. BPASS scores were not correlated with ethnicity or parent education; however, some domains were correlated with IQ. The BPASS holds promise as a quantitative phenotypic assessment for genetic studies. En ligne : http://dx.doi.org/10.1007/s10803-006-0182-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=656
in Journal of Autism and Developmental Disorders > 37-3 (March 2007) . - p.523-536[article] Quantitative Assessment of Autism Symptom-related Traits in Probands and Parents: Broader Phenotype Autism Symptom Scale [Texte imprimé et/ou numérique] / Geraldine DAWSON, Auteur ; Annette ESTES, Auteur ; Jeffrey MUNSON, Auteur ; Gerard SCHELLENBERG, Auteur ; Raphael BERNIER, Auteur ; Robert ABBOTT, Auteur . - 2007 . - p.523-536.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-3 (March 2007) . - p.523-536
Mots-clés : Broader-phenotype Genetics Quantitative-traits Index. décimale : PER Périodiques Résumé : Autism susceptibility genes likely have effects on continuously distributed autism-related traits, yet few measures of such traits exist. The Broader Phenotype Autism Symptom Scale (BPASS), developed for use with affected children and family members, measures social motivation, social expressiveness, conversational skills, and flexibility. Based on 201 multiplex families, psychometric data on the BPASS are reported. Adequate inter-rater reliability and internal consistency were found. Parents had lower BPASS scores than affected children, after controlling for IQ. Parents and affected children showed overlapping distributions suggesting the BPASS captured variability in traits across groups. BPASS scores were not correlated with ethnicity or parent education; however, some domains were correlated with IQ. The BPASS holds promise as a quantitative phenotypic assessment for genetic studies. En ligne : http://dx.doi.org/10.1007/s10803-006-0182-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=656