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Cell therapy approaches to autism: a review of clinical trial data / Jack PRICE in Molecular Autism, 11 (2020)
[article]
Titre : Cell therapy approaches to autism: a review of clinical trial data Type de document : Texte imprimé et/ou numérique Auteurs : Jack PRICE, Auteur Article en page(s) : 37 p. Langues : Anglais (eng) Mots-clés : Autism Cell therapy Clinical trials Stem cells Index. décimale : PER Périodiques Résumé : A number of clinical trials of cell therapies for autism spectrum disorder have been conducted, and some have published their outcomes. This review considers the data that have emerged from this small set of published trials, evaluates their success, and proposes further steps that could be taken if this field of endeavour is to be pursued further. A number of reservations arise from this tranche of studies, specifically the absence of identified therapeutic targets, and deficiencies in the therapeutic approach that is being employed. If this therapeutic direction is to be pursued further, then additional pre-clinical studies are recommended that might lead to improvements in patient stratification, biomarkers, the defined mode of action, and the preparation and identification of the therapeutic cells themselves. En ligne : http://dx.doi.org/10.1186/s13229-020-00348-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Molecular Autism > 11 (2020) . - 37 p.[article] Cell therapy approaches to autism: a review of clinical trial data [Texte imprimé et/ou numérique] / Jack PRICE, Auteur . - 37 p.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020) . - 37 p.
Mots-clés : Autism Cell therapy Clinical trials Stem cells Index. décimale : PER Périodiques Résumé : A number of clinical trials of cell therapies for autism spectrum disorder have been conducted, and some have published their outcomes. This review considers the data that have emerged from this small set of published trials, evaluates their success, and proposes further steps that could be taken if this field of endeavour is to be pursued further. A number of reservations arise from this tranche of studies, specifically the absence of identified therapeutic targets, and deficiencies in the therapeutic approach that is being employed. If this therapeutic direction is to be pursued further, then additional pre-clinical studies are recommended that might lead to improvements in patient stratification, biomarkers, the defined mode of action, and the preparation and identification of the therapeutic cells themselves. En ligne : http://dx.doi.org/10.1186/s13229-020-00348-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427