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Reward-related decision-making in pediatric major depressive disorder: an fMRI study / Erika E. FORBES in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)
[article]
Titre : Reward-related decision-making in pediatric major depressive disorder: an fMRI study Type de document : Texte imprimé et/ou numérique Auteurs : Erika E. FORBES, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; J. Christopher MAY, Auteur ; Greg J. SIEGLE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Neal D. RYAN, Auteur ; Cameron S. CARTER, Auteur ; Ronald E. DAHL, Auteur Année de publication : 2007 Article en page(s) : p.1031–1040 Langues : Anglais (eng) Mots-clés : Depression reward decision-making Index. décimale : PER Périodiques Résumé : Background: Although reward processing is considered an important part of affective functioning, few studies have investigated reward-related decisions or responses in young people with affective disorders. Depression is postulated to involve decreased activity in reward-related affective systems.
Methods: Using functional magnetic resonance imaging (fMRI), we examined behavioral and neural responses to reward in young people with depressive disorders using a reward decision-making task. The task involved choices about possible rewards involving varying magnitude and probability of reward. The study design allowed the separation of decision/anticipation and outcome phases of reward processing. Participants were 9–17 years old and had diagnoses of major depressive disorder (MDD), anxiety disorders, or no history of psychiatric disorder.
Results: Participants with MDD exhibited less neural response than control participants in reward-related brain areas during both phases of the task. Group differences did not appear to be a function of anxiety. Depressive and anxiety symptoms were associated with activation in reward-related brain areas.
Conclusions: Results suggest that depression involves altered reward processing and underscore the need for further investigation of relations among development, affective disorders, and reward processing.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01673.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=793
in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1031–1040[article] Reward-related decision-making in pediatric major depressive disorder: an fMRI study [Texte imprimé et/ou numérique] / Erika E. FORBES, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; J. Christopher MAY, Auteur ; Greg J. SIEGLE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Neal D. RYAN, Auteur ; Cameron S. CARTER, Auteur ; Ronald E. DAHL, Auteur . - 2007 . - p.1031–1040.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1031–1040
Mots-clés : Depression reward decision-making Index. décimale : PER Périodiques Résumé : Background: Although reward processing is considered an important part of affective functioning, few studies have investigated reward-related decisions or responses in young people with affective disorders. Depression is postulated to involve decreased activity in reward-related affective systems.
Methods: Using functional magnetic resonance imaging (fMRI), we examined behavioral and neural responses to reward in young people with depressive disorders using a reward decision-making task. The task involved choices about possible rewards involving varying magnitude and probability of reward. The study design allowed the separation of decision/anticipation and outcome phases of reward processing. Participants were 9–17 years old and had diagnoses of major depressive disorder (MDD), anxiety disorders, or no history of psychiatric disorder.
Results: Participants with MDD exhibited less neural response than control participants in reward-related brain areas during both phases of the task. Group differences did not appear to be a function of anxiety. Depressive and anxiety symptoms were associated with activation in reward-related brain areas.
Conclusions: Results suggest that depression involves altered reward processing and underscore the need for further investigation of relations among development, affective disorders, and reward processing.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01673.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=793