Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
1 recherche sur le mot-clé 'GABRA2'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Rule breaking mediates the developmental association between GABRA2 and adolescent substance abuse / Elisa M. TRUCCO in Journal of Child Psychology and Psychiatry, 55-12 (December 2014)
[article]
Titre : Rule breaking mediates the developmental association between GABRA2 and adolescent substance abuse Type de document : Texte imprimé et/ou numérique Auteurs : Elisa M. TRUCCO, Auteur ; Sandra VILLAFUERTE, Auteur ; Mary M. HEITZEG, Auteur ; Margit BURMEISTER, Auteur ; Robert A. ZUCKER, Auteur Article en page(s) : p.1372-1379 Langues : Anglais (eng) Mots-clés : GABRA2 rule breaking substance abuse adolescence mediation Index. décimale : PER Périodiques Résumé : Background This study's primary aim was to examine age-specific associations between GABRA2, rule breaking, problematic alcohol use, and substance abuse symptomatology. The secondary aim was to examine the extent to which rule breaking mediates the GABRA2-substance abuse relationship. Methods A sample (n = 518) of primarily male (70.9%) and White (88.8%) adolescents from the Michigan Longitudinal Study was assessed from ages 11–18. Age-specific effects of GABRA2 on rule breaking, problematic alcohol use, and substance abuse symptomatology were examined using nested path models. The role of rule breaking as a mediator in the association between GABRA2 and substance abuse outcomes was tested using prospective cross-lagged path models. Results GABRA2 is significantly (p 0.05) associated with rule breaking in mid- to late-adolescence, but not substance abuse symptomatology across adolescence. GABRA2 effects on problematic alcohol use and substance abuse symptomatology operate largely (45.3% and 71.1%, respectively, p 0.05) via rule breaking in midadolescence. Conclusions GABRA2 represents an early risk factor for an externalizing pathway to the development of problematic alcohol and drug use. En ligne : http://dx.doi.org/10.1111/jcpp.12244 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243
in Journal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1372-1379[article] Rule breaking mediates the developmental association between GABRA2 and adolescent substance abuse [Texte imprimé et/ou numérique] / Elisa M. TRUCCO, Auteur ; Sandra VILLAFUERTE, Auteur ; Mary M. HEITZEG, Auteur ; Margit BURMEISTER, Auteur ; Robert A. ZUCKER, Auteur . - p.1372-1379.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1372-1379
Mots-clés : GABRA2 rule breaking substance abuse adolescence mediation Index. décimale : PER Périodiques Résumé : Background This study's primary aim was to examine age-specific associations between GABRA2, rule breaking, problematic alcohol use, and substance abuse symptomatology. The secondary aim was to examine the extent to which rule breaking mediates the GABRA2-substance abuse relationship. Methods A sample (n = 518) of primarily male (70.9%) and White (88.8%) adolescents from the Michigan Longitudinal Study was assessed from ages 11–18. Age-specific effects of GABRA2 on rule breaking, problematic alcohol use, and substance abuse symptomatology were examined using nested path models. The role of rule breaking as a mediator in the association between GABRA2 and substance abuse outcomes was tested using prospective cross-lagged path models. Results GABRA2 is significantly (p 0.05) associated with rule breaking in mid- to late-adolescence, but not substance abuse symptomatology across adolescence. GABRA2 effects on problematic alcohol use and substance abuse symptomatology operate largely (45.3% and 71.1%, respectively, p 0.05) via rule breaking in midadolescence. Conclusions GABRA2 represents an early risk factor for an externalizing pathway to the development of problematic alcohol and drug use. En ligne : http://dx.doi.org/10.1111/jcpp.12244 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243