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Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development / Tania L. ROTH in Journal of Child Psychology and Psychiatry, 52-4 (April 2011)
[article]
Titre : Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development Type de document : Texte imprimé et/ou numérique Auteurs : Tania L. ROTH, Auteur ; J. David SWEATT, Auteur Année de publication : 2011 Article en page(s) : p.398-408 Langues : Anglais (eng) Mots-clés : Early-life experience maternal care epigenetic DNA methylation histone modification Index. décimale : PER Périodiques Résumé : Experiences during early development profoundly affect development of the central nervous system (CNS) to impart either risk for or resilience to later psychopathology. Work in the developmental neuroscience field is providing compelling data that epigenetic marking of the genome may underlie aspects of this process. Experiments in rodents continue to show that experiences during sensitive periods of development influence DNA methylation patterns of several genes. These experience-induced DNA methylation patterns represent stable epigenetic modifications that alter gene transcription throughout the lifespan and promote specific behavioral outcomes. We discuss the relevance of these findings to humans, and also briefly discuss these findings in the broader contexts of cognition and psychiatric disorder. We conclude by discussing the implications of these observations for future research. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02282.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119
in Journal of Child Psychology and Psychiatry > 52-4 (April 2011) . - p.398-408[article] Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development [Texte imprimé et/ou numérique] / Tania L. ROTH, Auteur ; J. David SWEATT, Auteur . - 2011 . - p.398-408.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-4 (April 2011) . - p.398-408
Mots-clés : Early-life experience maternal care epigenetic DNA methylation histone modification Index. décimale : PER Périodiques Résumé : Experiences during early development profoundly affect development of the central nervous system (CNS) to impart either risk for or resilience to later psychopathology. Work in the developmental neuroscience field is providing compelling data that epigenetic marking of the genome may underlie aspects of this process. Experiments in rodents continue to show that experiences during sensitive periods of development influence DNA methylation patterns of several genes. These experience-induced DNA methylation patterns represent stable epigenetic modifications that alter gene transcription throughout the lifespan and promote specific behavioral outcomes. We discuss the relevance of these findings to humans, and also briefly discuss these findings in the broader contexts of cognition and psychiatric disorder. We conclude by discussing the implications of these observations for future research. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02282.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 Epigenetic Factors in Normal and Pathological Neuronal Development / Natacha BROUCQSAULT
Titre : Epigenetic Factors in Normal and Pathological Neuronal Development Type de document : Texte imprimé et/ou numérique Auteurs : Natacha BROUCQSAULT, Auteur ; Cherif BADJA, Auteur ; Marie-Cécile GAILLARD, Auteur ; Frédérique MAGDINIER, Auteur Année de publication : 2015 Importance : p.183-215 Langues : Anglais (eng) Mots-clés : Epigenetics DNA methylation Long noncoding RNAs Histone modification Neuronal development Neurodevelopmental disorders Autistic spectrum disorders Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=265 Epigenetic Factors in Normal and Pathological Neuronal Development [Texte imprimé et/ou numérique] / Natacha BROUCQSAULT, Auteur ; Cherif BADJA, Auteur ; Marie-Cécile GAILLARD, Auteur ; Frédérique MAGDINIER, Auteur . - 2015 . - p.183-215.
Langues : Anglais (eng)
Mots-clés : Epigenetics DNA methylation Long noncoding RNAs Histone modification Neuronal development Neurodevelopmental disorders Autistic spectrum disorders Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=265 Exemplaires
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