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Goal Attainment Scaling as an Outcome Measure in Randomized Controlled Trials of Psychosocial Interventions in Autism / Lisa A. RUBLE in Journal of Autism and Developmental Disorders, 42-9 (September 2012)
[article]
Titre : Goal Attainment Scaling as an Outcome Measure in Randomized Controlled Trials of Psychosocial Interventions in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Lisa A. RUBLE, Auteur ; John H. MCGREW, Auteur ; Michael D. TOLAND, Auteur Année de publication : 2012 Article en page(s) : p.1974-1983 Langues : Anglais (eng) Mots-clés : Goal attainment scaling Outcome measurement Autism Randomized controlled trials Reliability Psychosocial intervention Index. décimale : PER Périodiques Résumé : Goal attainment scaling (GAS) holds promise as an idiographic approach for measuring outcomes of psychosocial interventions in community settings. GAS has been criticized for untested assumptions of scaling level (i.e., interval or ordinal), inter-individual equivalence and comparability, and reliability of coding across different behavioral observation methods. We tested assumptions of equality between GAS descriptions for outcome measurement in a randomized trial (i.e., measurability, equidistance, level of difficulty, comparability of behavior samples collected from teachers vs. researchers and live vs. videotape). Results suggest GAS descriptions can be evaluated for equivalency, that teacher collected behavior samples are representative, and that varied sources of behavior samples can be reliably coded. GAS is a promising measurement approach. Recommendations are provided to ensure methodological quality. En ligne : http://dx.doi.org/10.1007/s10803-012-1446-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180
in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1974-1983[article] Goal Attainment Scaling as an Outcome Measure in Randomized Controlled Trials of Psychosocial Interventions in Autism [Texte imprimé et/ou numérique] / Lisa A. RUBLE, Auteur ; John H. MCGREW, Auteur ; Michael D. TOLAND, Auteur . - 2012 . - p.1974-1983.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1974-1983
Mots-clés : Goal attainment scaling Outcome measurement Autism Randomized controlled trials Reliability Psychosocial intervention Index. décimale : PER Périodiques Résumé : Goal attainment scaling (GAS) holds promise as an idiographic approach for measuring outcomes of psychosocial interventions in community settings. GAS has been criticized for untested assumptions of scaling level (i.e., interval or ordinal), inter-individual equivalence and comparability, and reliability of coding across different behavioral observation methods. We tested assumptions of equality between GAS descriptions for outcome measurement in a randomized trial (i.e., measurability, equidistance, level of difficulty, comparability of behavior samples collected from teachers vs. researchers and live vs. videotape). Results suggest GAS descriptions can be evaluated for equivalency, that teacher collected behavior samples are representative, and that varied sources of behavior samples can be reliably coded. GAS is a promising measurement approach. Recommendations are provided to ensure methodological quality. En ligne : http://dx.doi.org/10.1007/s10803-012-1446-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials / Yue WANG in Research in Autism Spectrum Disorders, 64 (August 2019)
[article]
Titre : Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials Type de document : Texte imprimé et/ou numérique Auteurs : Yue WANG, Auteur ; Meng-Jie WANG, Auteur ; Ying RONG, Auteur ; Hui-Zhong HE, Auteur ; Chang-Jiang YANG, Auteur Article en page(s) : p.63-75 Langues : Anglais (eng) Mots-clés : Oxytocin Autism spectrum disorder Social function Repetitive behaviors Meta-analysis Randomized controlled trials Index. décimale : PER Périodiques Résumé : Background Evidence of oxytocin for treating core symptoms in autism spectrum disorder (ASD) across development remains mixed and establishing its role is critical for guiding therapy. Aim The current paper is aimed to include new studies and provide a stricter and updated meta-analysis to assess the oxytocin's effects on core symptoms in ASD. Method Computerized search was conducted in PubMed, EMBASE, Cochrane Library, PsycINFO, Web of Science Database and references in reviews from the earliest date available to September 2018. Randomized controlled trials (RCTs) were identified which evaluated the effectiveness of oxytocin on at least one of two domains in patients with ASD, namely social function and repetitive behaviors. Standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test. Results Sixteen studies comprising 520 individuals with ASD were included in this meta-analysis. Results suggested that oxytocin had a small and non-significant effect on social function [SMD?=?0.03, 95% CI (?0.19, 0.25), p?=?0.781] and repetitive behaviors [SMD?=?0.01, 95% CI (?0.26, 0.27), p?=?0.952] compared with placebo. Studies included had a low heterogeneity (I2?=?46.4%, p?=?0.025 in social function; I2?=?37.0%, p?=?0.123 in repetitive behaviors). Conclusions The current meta-analysis demonstrated that oxytocin had a small and non-significant effect on core symptoms in ASD population. With the limited number of included studies, more large-scale, rigorously and multi-site RCTs are needed to confirm the effectiveness of oxytocin as a treatment of ASD to acquire more convincing conclusions in the future. En ligne : https://doi.org/10.1016/j.rasd.2019.03.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=399
in Research in Autism Spectrum Disorders > 64 (August 2019) . - p.63-75[article] Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials [Texte imprimé et/ou numérique] / Yue WANG, Auteur ; Meng-Jie WANG, Auteur ; Ying RONG, Auteur ; Hui-Zhong HE, Auteur ; Chang-Jiang YANG, Auteur . - p.63-75.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 64 (August 2019) . - p.63-75
Mots-clés : Oxytocin Autism spectrum disorder Social function Repetitive behaviors Meta-analysis Randomized controlled trials Index. décimale : PER Périodiques Résumé : Background Evidence of oxytocin for treating core symptoms in autism spectrum disorder (ASD) across development remains mixed and establishing its role is critical for guiding therapy. Aim The current paper is aimed to include new studies and provide a stricter and updated meta-analysis to assess the oxytocin's effects on core symptoms in ASD. Method Computerized search was conducted in PubMed, EMBASE, Cochrane Library, PsycINFO, Web of Science Database and references in reviews from the earliest date available to September 2018. Randomized controlled trials (RCTs) were identified which evaluated the effectiveness of oxytocin on at least one of two domains in patients with ASD, namely social function and repetitive behaviors. Standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test. Results Sixteen studies comprising 520 individuals with ASD were included in this meta-analysis. Results suggested that oxytocin had a small and non-significant effect on social function [SMD?=?0.03, 95% CI (?0.19, 0.25), p?=?0.781] and repetitive behaviors [SMD?=?0.01, 95% CI (?0.26, 0.27), p?=?0.952] compared with placebo. Studies included had a low heterogeneity (I2?=?46.4%, p?=?0.025 in social function; I2?=?37.0%, p?=?0.123 in repetitive behaviors). Conclusions The current meta-analysis demonstrated that oxytocin had a small and non-significant effect on core symptoms in ASD population. With the limited number of included studies, more large-scale, rigorously and multi-site RCTs are needed to confirm the effectiveness of oxytocin as a treatment of ASD to acquire more convincing conclusions in the future. En ligne : https://doi.org/10.1016/j.rasd.2019.03.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=399 Screening, Intervention and Outcome in Autism and Other Developmental Disorders: The Role of Randomized Controlled Trials / Elisabeth FERNELL in Journal of Autism and Developmental Disorders, 44-8 (August 2014)
[article]
Titre : Screening, Intervention and Outcome in Autism and Other Developmental Disorders: The Role of Randomized Controlled Trials Type de document : Texte imprimé et/ou numérique Auteurs : Elisabeth FERNELL, Auteur ; Philip WILSON, Auteur ; Nouchine HADJIKHANI, Auteur ; Thomas BOURGERON, Auteur ; Brian NEVILLE, Auteur ; David C. TAYLOR, Auteur ; Helen MINNIS, Auteur ; Christopher GILLBERG, Auteur Article en page(s) : p.2074-2076 Langues : Anglais (eng) Mots-clés : Developmental disorders Autism Screening Randomized controlled trials Intervention Index. décimale : PER Périodiques Résumé : We draw attention to a number of important considerations in the arguments about screening and outcome of intervention in children with autism and other developmental disorders. Autism screening in itself never provides a final clinical diagnosis, but may well identify developmental deviations indicative of autism—or of other developmental disorders—that should lead to referral for further clinical assessment. Decisions regarding population or clinic screening cannot be allowed to be based on the fact that prospective longitudinal RCT designs over decades could never be performed in complex developmental disorders. We propose an alternative approach. Early screening for autism and other developmental disorders is likely to be of high societal importance and should be promoted and rigorously evaluated. En ligne : http://dx.doi.org/10.1007/s10803-014-2070-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236
in Journal of Autism and Developmental Disorders > 44-8 (August 2014) . - p.2074-2076[article] Screening, Intervention and Outcome in Autism and Other Developmental Disorders: The Role of Randomized Controlled Trials [Texte imprimé et/ou numérique] / Elisabeth FERNELL, Auteur ; Philip WILSON, Auteur ; Nouchine HADJIKHANI, Auteur ; Thomas BOURGERON, Auteur ; Brian NEVILLE, Auteur ; David C. TAYLOR, Auteur ; Helen MINNIS, Auteur ; Christopher GILLBERG, Auteur . - p.2074-2076.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-8 (August 2014) . - p.2074-2076
Mots-clés : Developmental disorders Autism Screening Randomized controlled trials Intervention Index. décimale : PER Périodiques Résumé : We draw attention to a number of important considerations in the arguments about screening and outcome of intervention in children with autism and other developmental disorders. Autism screening in itself never provides a final clinical diagnosis, but may well identify developmental deviations indicative of autism—or of other developmental disorders—that should lead to referral for further clinical assessment. Decisions regarding population or clinic screening cannot be allowed to be based on the fact that prospective longitudinal RCT designs over decades could never be performed in complex developmental disorders. We propose an alternative approach. Early screening for autism and other developmental disorders is likely to be of high societal importance and should be promoted and rigorously evaluated. En ligne : http://dx.doi.org/10.1007/s10803-014-2070-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236