Centre d'Information et de documentation du CRA Rhône-Alpes
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Is Valacyclovir a Mood Stabilizer / Theodore A HENDERSON in Autism - Open Access, 3-3 (December 2013)
[article]
Titre : Is Valacyclovir a Mood Stabilizer Type de document : Texte imprimé et/ou numérique Auteurs : Theodore A HENDERSON, Auteur Année de publication : 2013 Article en page(s) : 4 p. Langues : Anglais (eng) Mots-clés : Valacyclovir Autism Bipolar disorder Mood stabilizer Index. décimale : PER Périodiques Résumé : Growing evidence indicates the role of viral agents in neuropsychiatric conditions, such as chronic fatigue syndrome (CFS), Alzheimer’s disease, and possibly autism. This case report describes a patient who was afflicted with treatment-resistant childhood bipolar disorder, who also had features associated with attention deficit hyperactivity disorder and autism spectrum disorder. After failing multiple regimens for mood stabilization (anticonvulsants, lithium, neuroleptics), a trial of valacyclovir was initiated. The decision to use an antiviral agent was based on the patient’s laboratory data and the marked treatment response of the patient’s sibling, who manifested symptoms of depression and CFS. The patient in this report showed a dramatic improvement in his volatile mood, irritability, concentration, social reciprocity, and overall personality. He was maintained on valacyclovir at 1000 mg BID, while the doses of the mood stabilizing agents and stimulants were reduced by as much as 50%. After 37 months of ongoing valacyclovir treatment, the patient continues to make improvements and is being mainstreamed in school. The case illustrates a potential role of viruses in neuropsychiatric and psychiatric disorders and the potential benefit of antiviral therapy in treatment-refractory cases. En ligne : http://dx.doi.org/10.4172/2165-7890.1000118 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228
in Autism - Open Access > 3-3 (December 2013) . - 4 p.[article] Is Valacyclovir a Mood Stabilizer [Texte imprimé et/ou numérique] / Theodore A HENDERSON, Auteur . - 2013 . - 4 p.
Langues : Anglais (eng)
in Autism - Open Access > 3-3 (December 2013) . - 4 p.
Mots-clés : Valacyclovir Autism Bipolar disorder Mood stabilizer Index. décimale : PER Périodiques Résumé : Growing evidence indicates the role of viral agents in neuropsychiatric conditions, such as chronic fatigue syndrome (CFS), Alzheimer’s disease, and possibly autism. This case report describes a patient who was afflicted with treatment-resistant childhood bipolar disorder, who also had features associated with attention deficit hyperactivity disorder and autism spectrum disorder. After failing multiple regimens for mood stabilization (anticonvulsants, lithium, neuroleptics), a trial of valacyclovir was initiated. The decision to use an antiviral agent was based on the patient’s laboratory data and the marked treatment response of the patient’s sibling, who manifested symptoms of depression and CFS. The patient in this report showed a dramatic improvement in his volatile mood, irritability, concentration, social reciprocity, and overall personality. He was maintained on valacyclovir at 1000 mg BID, while the doses of the mood stabilizing agents and stimulants were reduced by as much as 50%. After 37 months of ongoing valacyclovir treatment, the patient continues to make improvements and is being mainstreamed in school. The case illustrates a potential role of viruses in neuropsychiatric and psychiatric disorders and the potential benefit of antiviral therapy in treatment-refractory cases. En ligne : http://dx.doi.org/10.4172/2165-7890.1000118 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228