Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
2 recherche sur le mot-clé 'brain abnormality'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Neonatal brain abnormalities associated with autism spectrum disorder in children born very preterm / Alexandra M. URE in Autism Research, 9-5 (May 2016)
[article]
Titre : Neonatal brain abnormalities associated with autism spectrum disorder in children born very preterm Type de document : Texte imprimé et/ou numérique Auteurs : Alexandra M. URE, Auteur ; Karli TREYVAUD, Auteur ; Deanne K. THOMPSON, Auteur ; Leona PASCOE, Auteur ; Gehan ROBERTS, Auteur ; Katherine J. LEE, Auteur ; Marc L. SEAL, Auteur ; Elisabeth NORTHAM, Auteur ; Jeanie L. CHEONG, Auteur ; Rod W. HUNT, Auteur ; Terrie INDER, Auteur ; Lex W. DOYLE, Auteur ; Peter J. ANDERSON, Auteur Article en page(s) : p.543-552 Langues : Anglais (eng) Mots-clés : preterm birth brain abnormality autism spectrum disorder magnetic resonance imaging neonatal imaging Index. décimale : PER Périodiques Résumé : Very preterm (VP) survivors are at increased risk of autism spectrum disorder (ASD) compared with term-born children. This study explored whether neonatal magnetic resonance (MR) brain features differed in VP children with and without ASD at 7 years. One hundred and seventy-two VP children (<30 weeks' gestation or <1250 g birth weight) underwent structural brain MR scans at term equivalent age (TEA; 40 weeks' gestation ±2 weeks) and were assessed for ASD at 7 years of age. The presence and severity of white matter, cortical gray matter, deep nuclear gray matter, and cerebellar abnormalities were assessed, and total and regional brain volumes were measured. ASD was diagnosed using a standardized parent report diagnostic interview and confirmed via an independent assessment. Eight VP children (4.7%) were diagnosed with ASD. Children with ASD had more cystic lesions in the cortical white matter at TEA compared with those without ASD (odds ratio [OR] 8.7, 95% confidence interval [CI] 1.5, 51.3, P?=?0.02). There was also some evidence for smaller cerebellar volumes in children with ASD compared with those without ASD (OR?=?0.82, CI?=?0.66, 1.00, P?=?0.06). Overall, the results suggest that VP children with ASD have different brain structure in the neonatal period compared with those who do not have ASD. En ligne : http://dx.doi.org/10.1002/aur.1558 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289
in Autism Research > 9-5 (May 2016) . - p.543-552[article] Neonatal brain abnormalities associated with autism spectrum disorder in children born very preterm [Texte imprimé et/ou numérique] / Alexandra M. URE, Auteur ; Karli TREYVAUD, Auteur ; Deanne K. THOMPSON, Auteur ; Leona PASCOE, Auteur ; Gehan ROBERTS, Auteur ; Katherine J. LEE, Auteur ; Marc L. SEAL, Auteur ; Elisabeth NORTHAM, Auteur ; Jeanie L. CHEONG, Auteur ; Rod W. HUNT, Auteur ; Terrie INDER, Auteur ; Lex W. DOYLE, Auteur ; Peter J. ANDERSON, Auteur . - p.543-552.
Langues : Anglais (eng)
in Autism Research > 9-5 (May 2016) . - p.543-552
Mots-clés : preterm birth brain abnormality autism spectrum disorder magnetic resonance imaging neonatal imaging Index. décimale : PER Périodiques Résumé : Very preterm (VP) survivors are at increased risk of autism spectrum disorder (ASD) compared with term-born children. This study explored whether neonatal magnetic resonance (MR) brain features differed in VP children with and without ASD at 7 years. One hundred and seventy-two VP children (<30 weeks' gestation or <1250 g birth weight) underwent structural brain MR scans at term equivalent age (TEA; 40 weeks' gestation ±2 weeks) and were assessed for ASD at 7 years of age. The presence and severity of white matter, cortical gray matter, deep nuclear gray matter, and cerebellar abnormalities were assessed, and total and regional brain volumes were measured. ASD was diagnosed using a standardized parent report diagnostic interview and confirmed via an independent assessment. Eight VP children (4.7%) were diagnosed with ASD. Children with ASD had more cystic lesions in the cortical white matter at TEA compared with those without ASD (odds ratio [OR] 8.7, 95% confidence interval [CI] 1.5, 51.3, P?=?0.02). There was also some evidence for smaller cerebellar volumes in children with ASD compared with those without ASD (OR?=?0.82, CI?=?0.66, 1.00, P?=?0.06). Overall, the results suggest that VP children with ASD have different brain structure in the neonatal period compared with those who do not have ASD. En ligne : http://dx.doi.org/10.1002/aur.1558 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289 Psychiatric outcomes at age seven for very preterm children: rates and predictors / Karli TREYVAUD in Journal of Child Psychology and Psychiatry, 54-7 (July 2013)
[article]
Titre : Psychiatric outcomes at age seven for very preterm children: rates and predictors Type de document : Texte imprimé et/ou numérique Auteurs : Karli TREYVAUD, Auteur ; Alexandra URE, Auteur ; Lex W. DOYLE, Auteur ; Katherine J. LEE, Auteur ; Cynthia E. ROGERS, Auteur ; Hiroyuki KIDOKORO, Auteur ; Terrie E. INDER, Auteur ; Peter J. ANDERSON, Auteur Article en page(s) : p.772-779 Langues : Anglais (eng) Mots-clés : Preterm psychiatric disorder brain abnormality predictor mental health Index. décimale : PER Périodiques Résumé : Background: Uncertainty remains about the rate of specific psychiatric disorders and associated predictive factors for very preterm (VPT) children. The aims of this study were to document rates of psychiatric disorders in VPT children aged 7 years compared with term born children, and to examine potential predictive factors for psychiatric diagnoses in VPT children. Methods: Participants were 177 VPT and 65 term born children. Perinatal medical data were collected, which included brain abnormalities detected using magnetic resonance imaging. The Infant-Toddler Social-Emotional Assessment (ITSEA) and Strengths and Difficulties Questionnaire (SDQ) were administered at 2 and 5 years respectively. At 7 years of age, the Developmental and Well-being Assessment (DAWBA) was used to indicate psychiatric diagnoses. Results: Compared with term born children, VPT children had three times the odds of meeting criteria for any psychiatric diagnosis at age 7 years (odds ratio 3.03; 95% confidence interval 1.23, 7.47, p = .02). The most common diagnoses were anxiety disorders (11% VPT, 8% term), attention-deficit/hyperactivity disorder (10% VPT, 3% term) and autism spectrum disorder (4.5% VPT, 0% term). For VPT children, those with severe global brain abnormalities (p = .02), those who displayed social-emotional problems at age 5 (p = .000) and those with higher social risk at age 7 (p = .001) were more likely to meet criteria for a psychiatric illness at age 7. Conclusions: Compared with term born children, VPT children have higher rates of psychiatric diagnoses at early school age, predicted by neonatal brain abnormalities, prior social-emotional problems and social factors. En ligne : http://dx.doi.org/10.1111/jcpp.12040 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203
in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.772-779[article] Psychiatric outcomes at age seven for very preterm children: rates and predictors [Texte imprimé et/ou numérique] / Karli TREYVAUD, Auteur ; Alexandra URE, Auteur ; Lex W. DOYLE, Auteur ; Katherine J. LEE, Auteur ; Cynthia E. ROGERS, Auteur ; Hiroyuki KIDOKORO, Auteur ; Terrie E. INDER, Auteur ; Peter J. ANDERSON, Auteur . - p.772-779.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.772-779
Mots-clés : Preterm psychiatric disorder brain abnormality predictor mental health Index. décimale : PER Périodiques Résumé : Background: Uncertainty remains about the rate of specific psychiatric disorders and associated predictive factors for very preterm (VPT) children. The aims of this study were to document rates of psychiatric disorders in VPT children aged 7 years compared with term born children, and to examine potential predictive factors for psychiatric diagnoses in VPT children. Methods: Participants were 177 VPT and 65 term born children. Perinatal medical data were collected, which included brain abnormalities detected using magnetic resonance imaging. The Infant-Toddler Social-Emotional Assessment (ITSEA) and Strengths and Difficulties Questionnaire (SDQ) were administered at 2 and 5 years respectively. At 7 years of age, the Developmental and Well-being Assessment (DAWBA) was used to indicate psychiatric diagnoses. Results: Compared with term born children, VPT children had three times the odds of meeting criteria for any psychiatric diagnosis at age 7 years (odds ratio 3.03; 95% confidence interval 1.23, 7.47, p = .02). The most common diagnoses were anxiety disorders (11% VPT, 8% term), attention-deficit/hyperactivity disorder (10% VPT, 3% term) and autism spectrum disorder (4.5% VPT, 0% term). For VPT children, those with severe global brain abnormalities (p = .02), those who displayed social-emotional problems at age 5 (p = .000) and those with higher social risk at age 7 (p = .001) were more likely to meet criteria for a psychiatric illness at age 7. Conclusions: Compared with term born children, VPT children have higher rates of psychiatric diagnoses at early school age, predicted by neonatal brain abnormalities, prior social-emotional problems and social factors. En ligne : http://dx.doi.org/10.1111/jcpp.12040 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203