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Psychotropic Medications in Children with Autism Spectrum Disorders: A Systematic Review and Synthesis for Evidence-Based Practice / Matthew SIEGEL in Journal of Autism and Developmental Disorders, 42-8 (August 2012)
[article]
Titre : Psychotropic Medications in Children with Autism Spectrum Disorders: A Systematic Review and Synthesis for Evidence-Based Practice Type de document : Texte imprimé et/ou numérique Auteurs : Matthew SIEGEL, Auteur ; Amy A. BEAULIEU, Auteur Année de publication : 2012 Article en page(s) : p.1592-1605 Langues : Anglais (eng) Mots-clés : Autism Evidence base Pharmacology Review Trials Index. décimale : PER Périodiques Résumé : This paper presents a systematic review, rating and synthesis of the empirical evidence for the use of psychotropic medications in children with autism spectrum disorders (ASD). Thirty-three randomized controlled trials (RCTs) published in peer-reviewed journals qualified for inclusion and were coded and analyzed using a systematic evaluative method specific to autism research (Reichow et al. in Journal of Autism and Developmental Disorders 38:1311–1319, 2008). Results are presented by agent and primary target symptom(s). The findings suggest established evidence for relatively few agents, with preliminary and promising evidence for a larger group. Challenges and opportunities in the developing field of ASD psychopharmacology are identified, and recommendations for further research are provided. En ligne : http://dx.doi.org/10.1007/s10803-011-1399-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178
in Journal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1592-1605[article] Psychotropic Medications in Children with Autism Spectrum Disorders: A Systematic Review and Synthesis for Evidence-Based Practice [Texte imprimé et/ou numérique] / Matthew SIEGEL, Auteur ; Amy A. BEAULIEU, Auteur . - 2012 . - p.1592-1605.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1592-1605
Mots-clés : Autism Evidence base Pharmacology Review Trials Index. décimale : PER Périodiques Résumé : This paper presents a systematic review, rating and synthesis of the empirical evidence for the use of psychotropic medications in children with autism spectrum disorders (ASD). Thirty-three randomized controlled trials (RCTs) published in peer-reviewed journals qualified for inclusion and were coded and analyzed using a systematic evaluative method specific to autism research (Reichow et al. in Journal of Autism and Developmental Disorders 38:1311–1319, 2008). Results are presented by agent and primary target symptom(s). The findings suggest established evidence for relatively few agents, with preliminary and promising evidence for a larger group. Challenges and opportunities in the developing field of ASD psychopharmacology are identified, and recommendations for further research are provided. En ligne : http://dx.doi.org/10.1007/s10803-011-1399-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 Stimulant ADHD medication and risk for substance abuse / Zheng CHANG in Journal of Child Psychology and Psychiatry, 55-8 (August 2014)
[article]
Titre : Stimulant ADHD medication and risk for substance abuse Type de document : Texte imprimé et/ou numérique Auteurs : Zheng CHANG, Auteur ; Paul LICHTENSTEIN, Auteur ; Linda HALLDNER, Auteur ; Brian M. D'ONOFRIO, Auteur ; Eva SERLACHIUS, Auteur ; Seena FAZEL, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur Article en page(s) : p.878-885 Langues : Anglais (eng) Mots-clés : ADHD pharmacology substance abuse Index. décimale : PER Périodiques Résumé : Background There are persistent concerns of long-term effects of stimulant ADHD medication on the development of substance abuse. Methods Using Swedish national registers, we studied all individuals born between 1960 and 1998 and diagnosed with ADHD (26,249 men and 12,504 women). We investigated the association between stimulant ADHD medication in 2006 and substance abuse during 2009. Substance abuse was indexed by substance-related death, crime, or hospital visits. Results ADHD medication was not associated with increased rate of substance abuse. Actually, the rate during 2009 was 31% lower among those prescribed ADHD medication in 2006, even after controlling for medication in 2009 and other covariates (hazard ratio: 0.69; 95% confidence interval: 0.57–0.84). Also, the longer the duration of medication, the lower the rate of substance abuse. Similar risk reductions were suggested among children and when investigating the association between stimulant ADHD medication and concomitant short-term abuse. Conclusions We found no indication of increased risks of substance abuse among individuals prescribed stimulant ADHD medication; if anything, the data suggested a long-term protective effect on substance abuse. Although stimulant ADHD medication does not seem to increase the risk for substance abuse, clinicians should remain alert to the potential problem of stimulant misuse and diversion in ADHD patients. En ligne : http://dx.doi.org/10.1111/jcpp.12164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237
in Journal of Child Psychology and Psychiatry > 55-8 (August 2014) . - p.878-885[article] Stimulant ADHD medication and risk for substance abuse [Texte imprimé et/ou numérique] / Zheng CHANG, Auteur ; Paul LICHTENSTEIN, Auteur ; Linda HALLDNER, Auteur ; Brian M. D'ONOFRIO, Auteur ; Eva SERLACHIUS, Auteur ; Seena FAZEL, Auteur ; Niklas LANGSTROM, Auteur ; Henrik LARSSON, Auteur . - p.878-885.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-8 (August 2014) . - p.878-885
Mots-clés : ADHD pharmacology substance abuse Index. décimale : PER Périodiques Résumé : Background There are persistent concerns of long-term effects of stimulant ADHD medication on the development of substance abuse. Methods Using Swedish national registers, we studied all individuals born between 1960 and 1998 and diagnosed with ADHD (26,249 men and 12,504 women). We investigated the association between stimulant ADHD medication in 2006 and substance abuse during 2009. Substance abuse was indexed by substance-related death, crime, or hospital visits. Results ADHD medication was not associated with increased rate of substance abuse. Actually, the rate during 2009 was 31% lower among those prescribed ADHD medication in 2006, even after controlling for medication in 2009 and other covariates (hazard ratio: 0.69; 95% confidence interval: 0.57–0.84). Also, the longer the duration of medication, the lower the rate of substance abuse. Similar risk reductions were suggested among children and when investigating the association between stimulant ADHD medication and concomitant short-term abuse. Conclusions We found no indication of increased risks of substance abuse among individuals prescribed stimulant ADHD medication; if anything, the data suggested a long-term protective effect on substance abuse. Although stimulant ADHD medication does not seem to increase the risk for substance abuse, clinicians should remain alert to the potential problem of stimulant misuse and diversion in ADHD patients. En ligne : http://dx.doi.org/10.1111/jcpp.12164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237