Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism / Estate M. SOKHADZE in Journal of Autism and Developmental Disorders, 39-4 (April 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-4 (April 2009) . - p.619-634 Titre : Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism Type de document : texte imprimé Auteurs : Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Lonnie L. SEARS, Auteur ; Ayman S. EL-BAZ, Auteur ; Grace MATHAI, Auteur ; Joshua M. BARUTH, Auteur Année de publication : 2009 Article en page(s) : p.619-634 Langues : Anglais (eng) Mots-clés : Autism Minicolumns Event-related-potentials Electroencephalography Gamma-frequencies Index. décimale : PER Périodiques Résumé : Previous studies by our group suggest that the neuropathology of autism is characterized by a disturbance of cortical modularity. In this model a decrease in the peripheral neuropil space of affected minicolumns provides for an inhibitory deficit and a readjustment in their signal to noise bias during information processing. In this study we proposed using low frequency transcranial magnetic stimulation (rTMS) as a way increasing the surround inhibition of minicolumns in autism. Thirteen patients (ADOS and ADI-R diagnized) and equal number of controls participated in the study. Repetitive TMS was delivered at 0.5 Hz, 2 times per week for 3 weeks. Outcome measures based on event-related potentials (ERP), induced gamma activity, and behavioral measures showed significant post-TMS improvement. The results suggest that rTMS offers a potential therapeutic intervention for autism. En ligne : http://dx.doi.org/10.1007/s10803-008-0662-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=706 [article] Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism [texte imprimé] / Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Lonnie L. SEARS, Auteur ; Ayman S. EL-BAZ, Auteur ; Grace MATHAI, Auteur ; Joshua M. BARUTH, Auteur . - 2009 . - p.619-634. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-4 (April 2009) . - p.619-634 Mots-clés : Autism Minicolumns Event-related-potentials Electroencephalography Gamma-frequencies Index. décimale : PER Périodiques Résumé : Previous studies by our group suggest that the neuropathology of autism is characterized by a disturbance of cortical modularity. In this model a decrease in the peripheral neuropil space of affected minicolumns provides for an inhibitory deficit and a readjustment in their signal to noise bias during information processing. In this study we proposed using low frequency transcranial magnetic stimulation (rTMS) as a way increasing the surround inhibition of minicolumns in autism. Thirteen patients (ADOS and ADI-R diagnized) and equal number of controls participated in the study. Repetitive TMS was delivered at 0.5 Hz, 2 times per week for 3 weeks. Outcome measures based on event-related potentials (ERP), induced gamma activity, and behavioral measures showed significant post-TMS improvement. The results suggest that rTMS offers a potential therapeutic intervention for autism. En ligne : http://dx.doi.org/10.1007/s10803-008-0662-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=706

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